Jurnal Indah Sains dan Klinis
Vol. 1 No. 1 (2020)

Aplikasi Metode Penetapan Kadar Rutin Parasetamol PT. Kimia Farma, Tbk secara HPLC pada Sediaan Tablet Generik dan Bermerek di Medan

Suprianto Suprianto (Program Studi Farmasi, Institut Kesehatan Helvetia, Medan, Indonesia)
Darwin Syamsul (Program Studi Farmasi, Institut Kesehatan Helvetia, Medan, Indonesia)
Muhammad Deddy Harfiansyah (Program Studi Farmasi, Institut Kesehatan Helvetia, Medan, Indonesia)

Article Info

Publish Date
10 Dec 2020

Abstract

Paracetamol is a drug that is analgesic and antipyretic, which is produced as a generic or branded drug. The research objective was to determine the quality based on paracetamol levels in generic and branded tablet preparations circulating in Medan. The research used HPLC Alliance e2696 UV / Visible Detector 2489, Column µ Bondapak TMC-18: 10 µm 125A 3.9x300 mm, UV-Vis Spectrophotometer Agilent 8453. The method used was a routine assay method for paracetamol PT. Kimia Farma. The results showed that the paracetamol content in the tablet dosage was 97.05% - 106.04%, according to the Indonesian Pharmacopoeia Edition V, not less than 90% and not more than 110%.

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Journal Info
Jurnal Indah Sains dan Klinis
Website

Abbrev

jisk

Publisher

Sekolah Tinggi Ilmu Kesehatan Indah Medan

Subject

Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing

Description

Jurnal Indah Sains dan Klinis adalah Jurnal tentang kesehatan yang mencakup sains dan klinis yang diterbitkan oleh Lembaga Penelitian dan Pengabdian pada Masyarakat (LPPM) STIKes Indah Medan yang meliputi kajian Ilmu Farmasi, Kedokteran, Keperawatan, Kebidanan, Kimia, Biologi, Mikrobiologi, Kultur ...