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INDONESIA
Jurnal Indah Sains dan Klinis
Published by Sekolah Tinggi Ilmu Kesehatan Indah Medan
ISSN : -     EISSN : 27471942     DOI : -
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing
Jurnal Indah Sains dan Klinis adalah Jurnal tentang kesehatan yang mencakup sains dan klinis yang diterbitkan oleh Lembaga Penelitian dan Pengabdian pada Masyarakat (LPPM) STIKes Indah Medan yang meliputi kajian Ilmu Farmasi, Kedokteran, Keperawatan, Kebidanan, Kimia, Biologi, Mikrobiologi, Kultur Jaringan dan disiplin ilmu lain yang terkait dengan kesehatan.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 40 Documents
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Aplikasi Metode Penetapan Kadar Rutin Parasetamol PT. Kimia Farma, Tbk secara HPLC pada Sediaan Tablet Generik dan Bermerek di Medan Suprianto Suprianto; Darwin Syamsul; Muhammad Deddy Harfiansyah
Journal of Indah Science and Clinic Vol. 1 No. 1 (2020)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.1

Abstract

Paracetamol is a drug that is analgesic and antipyretic, which is produced as a generic or branded drug. The research objective was to determine the quality based on paracetamol levels in generic and branded tablet preparations circulating in Medan. The research used HPLC Alliance e2696 UV / Visible Detector 2489, Column µ Bondapak TMC-18: 10 µm 125A 3.9x300 mm, UV-Vis Spectrophotometer Agilent 8453. The method used was a routine assay method for paracetamol PT. Kimia Farma. The results showed that the paracetamol content in the tablet dosage was 97.05% - 106.04%, according to the Indonesian Pharmacopoeia Edition V, not less than 90% and not more than 110%.
Korelasi Faktor Pemicu Kebiasaan Jajan Anak SD Al Khairiyah di Kecamatan Sunggal Kabupaten Deli Serdang Nur Asni Arti; Suprianto Suprianto
Journal of Indah Science and Clinic Vol. 1 No. 1 (2020)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.2

Abstract

Behavior originates from the impulse in humans which is an effort to meet human needs. Eating behavior that is often a problem is eating habits in canteens or stalls around school and eating fast food habits. The role of snacks in contributing energy or energy and protein substances is very significant, considering that school children get less protein intake and often snack, it is better if the snacks sold in the school canteen are high protein foods.This study aims to determine the factors associated with habitual snacking behavior. This was a non-experimental study through survey and observational approaches with a cross sectional sample of 96 students. Data collection includes eating habits, nutritional knowledge, breakfast habits, breakfast frequency, food carrying habits, pocket money, and types of food obtained through questionnaires. The data analyzed using Chi Square test. There are a relationship between nutritional knowledge, breakfast habits, carrying food, pocket money, and types of snacks with the snack habits of Al-Khairiyah Elementary School children, Sunggal District, Deli Serdang Regency. All factors are related to eating habits.
Pembuatan Hidrogel Berbasis Mikrokristal Selulosa Daun Nanas (Ananas comosus L. Merr) dengan Variasi Volume Glutaraldehid Muhammad Gunawan; Nanda Lestari
Journal of Indah Science and Clinic Vol. 1 No. 1 (2020)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.3

Abstract

Pineapple leaves natural fibers contain lignin, hemicellulose, and cellulose. The cellulose content of pineapple leaves is around 69.5% -71.5%. Cellulose-derived microcrystals can be used in the pharmaceutical field as binders in tableting formulations. The research objective was to determine whether pineapple leaves can produce microcrystals, microcrystals can be used in the manufacture of hydrogels and to determine variations in the volume of glutaraldehyde that can affect hydrogels. Experimetal research began with delignification with 4% NaOH, immersed for 1 hour and heated, washed with distilled water until neutral pH and blended with 2.7% NaOH, 7.9% acetic acid, NaOCl until white, heated, the residue was taken and drained. , soaked in 1 N HCl, reheated for 2 hours, re-stirred and blended until smooth. Cellulose hydrogel was dissolved in 8.5% NaOH and added with glutaraldehyde in various volume variations. Cellulose and hydrogel microcrystals were characterized by visual, swelling ratio test, FTIR, SEM and XRD. The yield of microcrystalline cellulose was 22%, white, homogeneous. Cellulose and hydrogel microcrystals contain O-H (3800-2700 cm-1), C-H (3000-2850 cm-1) and C-O (1300-800 cm-1) groups. Microcrystalline cellulose can be made from pineapple leaves, hydrogel formation is influenced by variations in the volume of glutaradehyde and the highest and lowest swelling ratios are 400% and 12.5%, respectively.
Penetapan Kadar Zink dalam Ikan Tongkol yang Beredar di Pasar Sei Sikambing secara Spektrofotometri Sinar Tampak Muhammad Gunawan; Ucha Gustamayanti
Journal of Indah Science and Clinic Vol. 1 No. 1 (2020)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.4

Abstract

Tuna as a seafood product that is often consumed by the public, has a high protein content and omega-3 fatty acids. The micro zinc mineral is needed, both for the synthesis and degradation of biomolecules as well as the role of enhancing the immune system. Zinc reacts with ditizone in a red base. Research to determine zinc content in raw, fried, steamed, and grilled tuna. Samples were taken purposively at the Sei Sikambing Medan traditional market, determination of levels using visible spectrophotometry, digestion with a solution of ditizone in alkaline. Method validation parameters include accuracy, precision, and sensitivity. Percent recovery of 100.50% and RSD 0.95%, LOD 0.620 ?g/ml and LOQ 2.066 ?g/ml. The zinc levels of raw, steamed, fried, and grilled tuna were 22.214 mg, 22.063 mg, 22.3384 mg, and 22.234 mg per 100g, respectively. ANOVA test, there is a significant difference in the acquisition of zinc levels in raw tuna, steamed tuna, grilled tuna, fried tuna. The method used is quite accurate. The zinc content of raw, fried, grilled tuna was higher than that of steamed, but there was no real difference.
Toksisitas Fraksi Sari n-Heksan Daun Kopasanda (Chromolaena odorata (L.) R.M King & H.Rob) terhadap Larva Udang dengan Metode BSLT (Brine Shrmp Lethality Test) Ayu Yolanda Ginting; Sumardi Sumardi; Vierza Mierza
Journal of Indah Science and Clinic Vol. 1 No. 1 (2020)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v1i1.5

Abstract

Kopasanda leaf plants (Chromolaena odorata (L.) R.M.King & H.Rob) are plants commonly used as medicinal ingredients empirically. The people of East Aceh use it as a wound medicine. Preliminary tests show that the extract and its partitions have a toxic effect on shrimp larvae. In this study, the soluble extract of n-hexane was fractionated using column chromatography with isocratic mobile phase n-hexane: ethyl acetate (7: 3) and silica gel stationary phase. Analysis of the chemical content profile using thin layer chromatography showed that there were polyphenol organic compounds. The fraction 7 obtained shows that it is toxic to shrimp larvae of Artemia salina Leach.
Potensi Antibakteri Kombinan Zingiber officinale Roscoe. Var. Rubrum dengan Cinnamomum burmannii terhadap Staphylococcus aureus Ruth Mayana Rumanti; Suprianto Suprianto; Jakub Tarigan; Arinri Misnangin Sritala Ramadani
Journal of Indah Science and Clinic Vol. 2 No. 1 (2021)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.8

Abstract

Red Ginger (Zingiber officinale Roscoe. Var. Rubrum) and Cinnamon (Cinnamomum burmannii) contain alkaloids, flavonoids, saponins, tannins, triterpenoids and essential oils. which is antibacterial that causes pharyngitis by Staphylococcus aureus. This study aims to determine the antibacterial potency of the combination of Red Ginger (Zingiber officinale Roscoe. Var. Rubrum) and Cinnamon (Cinnamomum burmannii) extract against Staphylococcus aureus. Experimental research includes the extraction of the compound components in red ginger and cinnamon by maceration with 70% ethanol. Inhibition was tested by diffusion method. Combination of concentration of Red Ginger and Cinnamon extracts of 5% : 40%; 10%: 30%; 20%: 20%; 30%: 10% and 40%: 5%. The combination of red ginger and cinnamon extract has antibacterial activity against pharyngitis-causing bacteria, namely Staphylococcus aureus with a strong response at a concentration of 5%: 40%.
Efektifitas Lotion Anti Nyamuk Ekstrak Etanol Daun Kenikir (Cosmos caudatus) Suprianto Suprianto; Hendri Faisal; Endang Subekti
Journal of Indah Science and Clinic Vol. 2 No. 1 (2021)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.9

Abstract

Mosquitoes are one of the insects whose presence is often disturbing. Plants of Kenikir (Cosmos caudatus) contains saponins, polyphenols, and volatile oils. This study uses an experimental method. Tests carried out include: organoleptic, homogeneity, pH, and effectiveness. The results showed that Kenikir leaf extract has effectiveness in resisting mosquitoes. Organoleptic test of lotion with a concentration of 5%, 10%, and 15% have a dark green colour and has a distinctive odour of Kenikir. Homogeneity test of lotion with a concentration of 5% is homogeneous, while concentrations of 10% and 15% are not homogeneous. Homogeneity and organoleptic tests have fulfilled the requirements of mosquitoes repellent lotion. The resulting lotion effectively repels mosquitoes
Uji Kadar Timbal (Pb) pada Ikan Teri dan Cumi Kering yang Beredar di Pasar Sambu Medan secara Spektrofotometri Serapan Atom Hendri Faisal; Fitria Wati; Dwi Setio Purnomo
Journal of Indah Science and Clinic Vol. 2 No. 1 (2021)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.10

Abstract

Anchovies and squid are one of the most abundant fishery resources in Indonesian waters. There is an increase in the concentration of heavy metals such as lead in marine waters which is caused by industrial waste, both solid and liquid waste, so that marine biota such as anchovies and squid accumulate these heavy metals. The very high level of heavy metal toxicity can have adverse effects on public health. The aim of this study was to determine the lead content and determine the amount of levels in dried anchovies and dried squid circulating in Sambu Market, Medan City. This research used atomic absorption spectrophotometric method at a wavelength of 283.8 nm. The results showed that dried anchovies and dried squid contained lead with the highest levels in dried anchovies was 7.04 mg / kg and the levels in dried squid were 6.65 mg / kg. The metal content of lead in dried anchovies and dried squid has exceeded the maximum standard set by the Indonesian National Standard (SNI Number 7387 of 2009), namely 0.3 mg / kg in fish and their processed products, while 1.5 mg / kg in mollusks.
Aktivitas Antibakteri Daun Kemangi (Ekstrak, Fraksi Kloroform, dan Fraksi n-Heksan) terhadap Staphylococcus aureus dan Eschericia coli Melati Yulia Kusumastuti; Debi Meilani; Suhendra Tawarnate
Journal of Indah Science and Clinic Vol. 2 No. 1 (2021)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.11

Abstract

Basil (Ocimum citriodorum Vis.) is a plant which is their leaves are commonly eaten as fresh vegetables and has many benefits. Basil leaves contains secondary metabolite compounds that have antibacterial activity such as flavonoids, tannins, saponins, alkaloids, and steroids. The purpose of this study was to known the antibacterial activity of some fractions of basil leaves against Escherichia coli and Staphylococcus aureus and see which fraction was more active.This research included extraction by maceration method using ethanol 96%, then ethanol extract was fractionated using n-hexane and chloroform, phytochemical screening, then tested for antibacterial activity against E. coli and S. aureus by using agar diffusion method. Phytochemical screening showed ethanol extract contained alkaloids, saponins, flavonoids, tannins and steroids; chloroform fraction contained alkaloids, flavonoids, saponins, and tannins; and n-hexane fraction contained steroids. The results of the antibacterial activity test showed ethanol extract and chloroform fraction had antibacterial activity. Meanwhile, n-hexane fraction did not have antibacterial activity. Concentration of 500 mg / ml of chloroform fraction and ethanol extract on S. aureus resulted inhibition zone around 24.67-26.90 mm. Furthermore, on E. coli produced 22.67-23.84 mm. Ethanol extract had higher antibacterial activity than the chloroform fraction against E. coli and S. aureus.
Hubungan Dukungan dan Pengetahuan Orang Tua dengan Motivasi Berkhitan Siswa MIS Amal Shaleh Perumnas Simalingkar Medan di Masa Pandemi Covid-19 Erika Erika; Wina Viqa Sari
Journal of Indah Science and Clinic Vol. 2 No. 1 (2021)
Publisher : LPPM STIKes Indah Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v2i1.12

Abstract

During the Covid-19 pandemic, people in Medan experienced anxiety. This is indicated by the community's low interest in circumcising their children, which is seen from the number of circumcision participants carried out by the Indah Foundation at the Indah Medan College of Health Sciences in 2020, in January with only 12 participants, 9 (June), 15 (October). Likewise on Radio Indah Suara 96.5 FM Perbaungan in December 2019 with 11 people, in June 2020 with 14 people, in October with 15 participants. This paper aims to determine the relationship between parent's support and knowledge for motivating their children to do circumcision. The method is done by looking at the correlation between parent's support and knowledge with the motivation to circumcise the child and seeing how multiple (simultaneous) correlation between the support and knowledge of parents and the motivation to circumcise the child. The author can conclude that the majority of students' parents (55%) do not support their children being circumcised during the Covid-19 pandemic, and parents' knowledge of circumcision during the Covid-19 pandemic is still inadequate, seen from the level of understanding of parents regarding circumcision during the Covid-19 pandemic is at a moderate level (66.67%).

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