Bioscientia Medicina : Journal of Biomedicine and Translational Research
Vol. 5 No. 11 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research

Dermatoglyphy in Breast Cancer Patients: A Systematic Review

Rara Inggarsih (Department of Biology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Akhyar Dyni Zakyah (Department of Dentistry, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Lusia Hayati (Department of Biology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Joko Marwoto (Department of Biology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Septi Purnamasari (Department of Biology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Arwan Bin Laeto (Department of Physiology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Masayu Farah Diba (Department of Microbiology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)



Article Info

Publish Date
23 Jun 2021

Abstract

Background. Breast cancer is one of the four types of cancer among women and is the most frequently diagnosed in most countries. Breast cancer occurs due to DNA damage and genetic mutations affected by exposure to estrogen, inheritance of damaged DNA, or pro-cancer genes such as BRCA1 and BRCA2. Therefore, a family history of ovarian cancer or breast cancer increases the risk of developing breast cancer. The embryo of the breast develops around the age of 6 weeks of pregnancy. Similar to breast development, fingerprint patterns also develop during the 6-13 weeks of pregnancy. Thus, the genetic message contained in the genome occurred during that period and was reflected in the dermatoglyphic pattern.Methods. The literature search was systematically used using PubMed, Cochran, Google scholar, and other Gray literature between 2010-2020. Of the 69 publications identified, 21 met the criteria and were included in the review. The review is carried out following the provisions of PRISMA (Preferred Reporting Items for Systematic Review).Results. This systematic review showed fairly consistent findings in breast cancer patients who tended to have more whorl fingerprint patterns and larger ATD angles. For radial loops, ulnar loops and arches were minor compared to the control group potential as an initial screening tool in at-risk groups.Conclusion. Long-term and follow-up studies with larger sample sizes in various ethnicities are needed to validate dermatoglyphics in anthropometric measurements as a promising marker of breast cancer.

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Journal Info

Abbrev

bsm

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

Description

BioScientia Medicina is an open access international scholarly journal in the field of biomedicine and translational research aimed to publish a high-quality scientific paper including original research papers, reviews, short communication, and technical notes. This journal welcomes the submission ...