Journal of Mathematical and Fundamental Sciences
Vol. 53 No. 2 (2021)

Analysis of SIS-SI Stochastic Model with CTMC on the Spread of Malaria Disease

Niswah Yanfa Nabilah Syams (Department of Mathematics, Bogor Agricultural University, Jl. Meranti, Kampus IPB Dramaga, Bogor 16680, Indonesia)
Hadi Sumarno (Department of Mathematics, Bogor Agricultural University, Jl. Meranti, Kampus IPB Dramaga, Bogor 16680, Indonesia)
Paian Sianturi (Department of Mathematics, Bogor Agricultural University, Jl. Meranti, Kampus IPB Dramaga, Bogor 16680, Indonesia)



Article Info

Publish Date
02 Aug 2021

Abstract

Various mathematical models have been developed to describe the transmission of malaria disease. The purpose of this study was to modify an existing mathematical model of malaria disease by using a CTMC stochastic model. The investigation focused on the transition probability, the basic reproduction number (R0), the outbreak probability, the expected time required to reach a disease-free equilibrium, and the quasi-stationary probability distribution. The population system will experience disease outbreak if R0>1, whereas an outbreak will not occur in the population system if R0≤1. The probability that a mosquito bites an infectious human is denoted as k, while θ is associated with human immunity. Based on the numerical analysis conducted, k and θ have high a contribution to the distribution of malaria disease. This conclusion is based on their impact on the outbreak probability and the expected time required to reach a disease-free equilibrium.

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Journal Info

Abbrev

jmfs

Publisher

Subject

Astronomy Chemistry Earth & Planetary Sciences Mathematics Physics

Description

Journal of Mathematical and Fundamental Sciences welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Astronomy, Chemistry, Earth Sciences (Geodesy, Geology, Geophysics, Oceanography, Meteorology), Life Sciences (Agriculture, Biochemistry, ...