Respiratory Science
Vol. 2 No. 1 (2021): Respiratory Science

The Association Between Vitamin D Receptor Gene FokI Polymorphism and Pulmonary Tuberculosis

Dina Octafrida Marpaung (Universitas Sumatera Utara)
Bintang Yinke Magdalena Sinaga (Universitas Sumatera Utara)
Parluhutan Siagian (Universitas Sumatera Utara)
Erna Mutiara (Universitas Sumatera Utara)

Article Info

Publish Date
15 Oct 2021

Abstract

Backgrounds: There is a wide range of individual responses to mycobacterium infection. However, the reason why certain people suffers from a disease when they are infected with mycobacterium while others remain healthy is still unknown. Genetic susceptibility is thought to be one of the important explanatory factors for individuals with the risk of developing pulmonary tuberculosis (TB). FokI polymorphism was one of the genetic variations within the vitamin D receptor (VDR) gene associated with pulmonary TB. In the present study, we investigated the association between VDR gene FokI polymorphism and pulmonary TB. Conclusion: There was no significant association between the VDR gene FokI polymorphism and pulmonary TB.

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Journal Info
Respiratory Science
Website

Abbrev

journal

Publisher

Perhimpunan Dokter Paru Indonesia

Subject

Health Professions Medicine & Pharmacology

Description

Focuses on original article reviews and case reports in pulmonary and critical care medicine Scope: 1. Asthma 2. Chronic Obstructive Pulmonary Disease (COPD) 3. Lung Physiology and Sleep-Related Disorder 4. Lung Infection 5. Thoracic Oncology 6. Interstitial Lung Disease 7. Environmental Lung ...