JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH
Vol. 2 No. 2 (2021): Journal of Community Medicine and Public Health Research

COMPARISON OF MORTALITY BETWEEN THE COMBINATION OF STANDARD THERAPY AND CONVALESCENT PLASMA THERAPY AND STANDARD THERAPY ONLY IN COVID-19 PATIENTS : SYSTEMATIC REVIEW AND META-ANALYSIS

Klarin, Felicia (Unknown)
Vita, Angelica Diana (Unknown)
Siahaan, Cynthia Elvira Sari (Unknown)
Rifdah, Salsabila Nabilah (Unknown)
Putri, Ayu Rahmanita (Unknown)
Kusuma, Indriasti Putri (Unknown)
Prayitno, Subur (Unknown)



Article Info

Publish Date
29 Oct 2021

Abstract

Coronavirus Disease-19 (COVID-19) is an infectious disease caused by a newly discovered type of coronavirus. Comprehensive management for COVID-19 patients includes infection control, hemodynamic stability maintenance, oxygenation monitoring, ventilation, and pharmacotherapy administration. Convalescent plasma is one of the COVID-19 therapy choices, proven to provide relief for Ebola, SARS, and MERS patients. Therefore, the authors believed in searching data on whether convalescent plasma therapy also improves COVID-19 patients, specifically in terms of mortality. This study aims to compare the comparison in mortality between standard therapy and convalescent plasma therapy with standard therapy only in COVID-19 patients. This study used a systematic review and meta-analysis method according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. This study used ten studies that met the inclusion criteria to evaluate the comparison in mortality between the combination therapy with standard therapy only in COVID-19 patients. There was a significant difference in mortality between the combination of standard therapy and convalescent plasma therapy with standard therapy only in COVID-19 patients, and mortality in the combination therapy groups being lower than standard therapy only.

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Journal Info

Abbrev

JCMPHR

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Public Health Research (JCMPHR) publishes articles in the field of community medicine and public health focusing on family health care, epidemiology, biostatistics, public health administration, management of health, national health problems, social medicine, nutrition and enviromental and ...