Journal of Mathematical and Fundamental Sciences
Vol. 53 No. 2 (2021)

Isolation and Antibacterial Properties of Phenyl Acrylic Acid Derivatives from Balanophora elongata Blume

Nanda Putra (School of Pharmacy, Bandung Institute of Technology, Jl. Tamansari 64. Bandung, Indonesia, 40116)
Goldha Faroliu (Faculty of Pharmacy/Sumatran Biota Laboratory, Andalas University, Kampus Limau Manis, Padang, West Sumatra, Indonesia, 25163)
Nova Syafni (Faculty of Pharmacy/Sumatran Biota Laboratory, Andalas University, Kampus Limau Manis, Padang, West Sumatra, Indonesia, 25163)
Nofrizal (Department of Pharmacy, Dharma Andalas University, Jl. Sawahan 103 Simpang Haru, Padang, West Sumatra, Indonesia, 25123)
Amri Bakhtiar (Department of Pharmacy, Faculty of Medicine, Baiturrahmah University, Jl. Bypass Km15, Padang, West Sumatra, Indonesia, 25886)
Dayar Arbain (Faculty of Pharmacy, University 17 Agustus 1945, Jl. Sunter Raya Permai, Jakarta, 14350)



Article Info

Publish Date
17 Sep 2021

Abstract

Balanophora elongata (Balanophoraceae) is a tropical parasitic flowering plant 9 cm in height. Four known phenyl acrylic acid derivatives, methyl caffeate (1), caffeic acid (2), 1,6-di-O-caffeoyl-β-D-glucopyranose (3), and coniferin (4), were isolated from this plant. Structural elucidation of the isolated compounds was determined by IR, LC-ESI-MS, 1D and 2D NMR.  Extracts and isolated compounds were tested toward some standard human pathogenic bacteria using the agar disk diffusion method. Their inhibition zones were compared to that of chloramphenicol as positive control. Compound 1 showed inhibition toward Streptococcus mutans, while compound 3 and 4 inhibited Staphylococcus aureus.

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Journal Info

Abbrev

jmfs

Publisher

Subject

Astronomy Chemistry Earth & Planetary Sciences Mathematics Physics

Description

Journal of Mathematical and Fundamental Sciences welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Astronomy, Chemistry, Earth Sciences (Geodesy, Geology, Geophysics, Oceanography, Meteorology), Life Sciences (Agriculture, Biochemistry, ...