Indian Journal of Forensic Medicine & Toxicology
Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

The Correlation of Congenital Anomalies of The Kidney and Urinary Tract with Renal Function in Children

Chairunnisa (Unknown)
Ninik Asmaningsih Soemyarso (Unknown)
Risky Vitria Prasetyo (Unknown)



Article Info

Publish Date
24 Mar 2021

Abstract

Background: Congenital Anomalies Kidney and Urinary Tract (CAKUT) are the leading cause of kidneyfailure in children and cause of 30-40% end-stage renal disease with obstructive uropathy as the main cause.CAKUT obstructive type are: vesico uretric junction obstruction (VUJO), pelvic uretric junction obstruction(PUJO), posterior uretral valve (PUV) and non-obstructive type are reflux, neurogenic and hypoplasia. Theaim of this study is to describe the effect of CAKUT on renal function in child.Methods: Retrospective study from medical records of children with CAKUT at Dr. Soetomo GeneralHospital, Surabaya, Indonesia from January 2013 - March 2018. The characteristic of sex, age range, type ofCAKUT and glomerulus filtration (GFR) value were recorded from medical record. Data processing usingdescriptive analysis with SPSS.Result: A total of 94 Children on CAKUT abnormalities, both boys and girl’s presentation equal 50%.Median age 3.0 (minimum-maximum 1.0-15.0) year. The most common CAKUT type in male were VUJO17 (36.2%) and in female neurogenic type 19 (40.4%). Median initial glomerular filtration rate 2.7 ml/min/1.73 m2. Analysis of correlation between CAKUT and renal function p=0.072 (R2=0,03). From 94children of CAKUT, only 12 (12.8%) patients have undergo surgical intervention.Conclusion: CAKUT with dominant obstructive type was more common in male and non-obstructive typein female pediatric patient. There was no significance correlation of GFR between obstructive and nonobstructive type.

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