<![CDATA["COVID-19" (Coronavirus Disease 2019) was officially announced by WHO on February 11th, 2020 as a new disease. SARS-CoV-2 infection in humans causes symptoms of acute respiratory disorders. In NTT province there has been 6,365 confirmed positive corona, with 2,924 of whom were in Kupang City. One way to prevent the spread of the pandemic is with a vaccine. In Kupang City, 39,896 or 4.54% of the provincial target had received stage 1 and 2 of vaccinations. This was still far from the expected target. To find out the relationship between the knowledge level and the anxiety level of the community of Kupang City on the COVID-19 vaccine. This research was an observational analytic study using a cross-sectional method. The sample in this study was selected using non-probability sampling with a total of 232 respondents. This study was analyzed by univariate and bivariate analysis using the Somers'd correlation test, after that a comparative test using Mann Whitney. The results showed that 220 respondents (94.8%) had a good knowledge level, 9 respondents (3.9%) had a moderate knowledge level and 3 respondents (1.3%) had a low knowledge level. Then 224 respondents (96.6%) did not experience anxiety disorders, 7 respondents (3.0%) had mild anxiety disorders, and 1 respondent (0.4%) had moderate anxiety disorders. The results of the bivariate test using the Somers'd correlation test showed p = 0.022 or p < 0.05 indicating that there was a significant relationship between the knowledge level and the anxiety level of the community of Kupang City on the COVID-19 vaccine. The results of the Mann Whitney test showed p = 0.497 or p > 0.05 indicating that there was no significant difference between the anxiety levels of respondents who have not and those who have received the COVID-19 vaccine. There was a significant relationship between the knowledge level and the anxiety level of the community of Kupang City on the COVID-19 vaccine. There was no significant difference between the anxiety level of respondents who have not and those who have received the COVID-19 vaccine.]]>
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