Jurnal Sains dan Teknologi
Vol. 1 No. 3 (2022): Juni 2022

Aktivitas Antibakteri Ekstrak Etanol Daun Pepaya (Carica papaya Linn.) Terhadap Bakteri Pseudomonas aeruginosa

Nasri Nasri (Sekolah Tinggi Ilmu Kesehatan (STIKes) Senior Medan)
Vera Estefania Kaban (Sekolah Tinggi Ilmu Kesehatan (STIKes) Senior Medan)
Kasta Gurning (Sekolah Tinggi Ilmu Kesehatan (STIKes) Senior Medan)
Hariyadi Dharmawan Syahputra (Sekolah Tinggi Ilmu Kesehatan (STIKes) Senior Medan)
Denny Satria (Universitas Sumatera Utara)

Article Info

Publish Date
28 Jun 2022

Abstract

Pseudomonas aeruginosa is a Gram-negative bacterium that can cause nosocomial infections. The use of antibiotics in the treatment of non-adherent P. aeruginosa infections increases the risk of antibiotic resistance. Efforts to find new antibiotic compounds from plants continue to be carried out. Papaya leaves are widely spread among the public, which are often used as ingredients for vegetables and have antibacterial potential because they contain papain enzymes and a class of flavonoid compounds. The purpose of this study was to analyze the antibacterial activity of the ethanol extract of papaya leaves (Carica papaya Linn.) against P. aeruginosa by finding the value of the Minimum Inhibitory Concentration (MIC) and calculating the index activity value against the positive control. The method used in this research is Kirby-Bauer (disc diffusion method) with several variations of the test concentration. The results showed that the diameter of the inhibition zone at a concentration of 500 mg/mL was in the strong category with an inhibition zone diameter of 10.87 ± 0.06 mm. MIC at a concentration of 3.125 mg/mL. The index activity value was greatest at a concentration of 500 mg/mL with a value of 0.668. So it can be concluded that the ethanol extract of papaya leaves (Carica papaya Linn.) has inhibitory activity against Pseudomonas aeruginosa.

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Journal Info
Jurnal Sains dan Teknologi
Website

Abbrev

insologi

Publisher

Yayasan Literasi Sains Indonesia

Subject

Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Electrical & Electronics Engineering Energy Engineering Health Professions Industrial & Manufacturing Engineering Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

Description

INSOLOGI (Jurnal Sains dan Teknologi) diterbitkan 6 (enam) kali dalam setahun, yaitu pada bulan Februari, April, Juni, Agustus, Oktober dan Desember oleh Yayasan Literasi Sains Indonesia. Jurnal INSOLOGI adalah jurnal yang dapat diakses secara terbuka bagi para Peneliti, Dosen dan Mahasiswa yang ...