AgriHealth: Journal of Agri-food, Nutrition and Public Health
Vol 3, No 2 (2022): October

Trends in IgG Antibody Levels in Covid-19 Patients in Different Clinical Manifestations in Bengkulu City: Cohort Study

Debie Rizqoh (Department of Microbiology, Faculty of Medicine and Health Sciences, Bengkulu University, Bengkulu)
Enny Nugrahaeni (Department of Microbiology, Faculty of Medicine and Health Sciences, Bengkulu University, Bengkulu)
Mulya Sundari (Department of Microbiology, Faculty of Medicine and Health Sciences, Bengkulu University, Bengkulu
Department of Internal Medicine Specialist, M. Yunus Hospital Center, Bengkulu)

Dessy Triana (Department of Parasitology, Faculty of Medicine and Health Sciences, Bengkulu University, Bengkulu)
Mardhatillah Sariyanti (Department of Microbiology, Faculty of Medicine and Health Sciences, Bengkulu University, Bengkulu)
Nikki Aldi Massardi (Department of Anatomical Pathology, Faculty of Medicine and Health Sciences, Bengkulu University, Bengkulu)



Article Info

Publish Date
29 Jun 2022

Abstract

More than two years have lasted since the coronavirus disease 2019 (Covid-19) pandemic. The case of Covid-19 in Indonesia has spread to all provinces and areas such as Bengkulu City. This study aims to determine the profile of clinical manifestations and antibody dynamics in Covid-19 patients in Bengkulu City. This study used a cohort design on Covid-19 patients at two Bengkulu City referral hospitals, M. Yunus Hospital and Harapan dan Doa Hospital. Data on clinical manifestations were obtained from the medical records of Covid-19 patients. Meanwhile, to determine the level of IgM and IgG antibodies, patient serum samples were taken directly from respondents from the beginning of hospital admission three times on the 1st, 2nd and 3rd weeks. Then the samples were examined by immunofluorescent assay method. The results of this study indicate that, in general, there are no significant differences in anti-SARS-CoV-2 IgG levels in Covid-19 patients in the 1st, 2nd and 3rd weeks of Covid-19 in Bengkulu City. The Spearman correlation test also showed no correlation between IgG levels and the clinical manifestations of Covid-19. Although not statistically significant, there was a trend towards differences in antibody levels in patients with mild, moderate and severe clinical manifestations. The results of this study indicate that there are variations in antibody dynamics in Covid-19 patients in Bengkulu City.

Copyrights © 2022






Journal Info

Abbrev

agrihealth

Publisher

Subject

Agriculture, Biological Sciences & Forestry Education Environmental Science Health Professions Public Health

Description

AgriHealth: Journal of Agri-food, Nutrition and Public Health merupakan wadah publikasi ilmiah hasil kajian penerapan ilmu pengetahuan dan teknologi kepada para pemangku kepentingan (stakeholder) di bidang pertanian ramah lingkungan, pangan, gizi dan kesehatan masyarakat yang meliputi: Budidaya ...