This study aims to assess the effectiveness of Video Directly Observed Therapy (VDOT) compared to Directly Observed Therapy (DOT) in improving medication adherence in TB patients. The method used is a systematic review using the CINAHL, PubMed, and Scopus databases. The results showed that 2 articles discussed routine treatment monitoring for face-to-face DOT at the patient's home or agreed with location during weekdays, and 8 articles discussed DOT by meeting with health department staff at TB clinics (clinic-based DOT. There were 5 articles using VOT intervention by sending videos (asynchronously) using a software application and 6 articles using VDOT conducting live video conferences while taking TB drugs. Keywords: Directly Observed Therapy, Tuberculosis, Video Observed Therapy
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