<![CDATA[Abstract: The purpose of this study was to determine the feasibility and response of students to interactive multimedia based on android containing critical thinking skills on mutation material. This type of research is research and development (R and D), this research was developed using the ADDIE development model (Analysis, Design, Development, Implementation, Evaluation). The sample in this study were 10 students of MAN 2 Semarang. The results of the study 76 percent of media experts, 81.81 percent of material experts, 90 percent of critical thinking experts, 91.61 percent of teacher responses, and 92.66 percent of student responses to interactive multimedia applications. Based on the results of the study, it can be concluded that android-based interactive multimedia to train critical thinking skills on mutasu material is very feasible to be used as teaching material. Keywords: critical thinking skills, interactive multimedia, development research. Abstrak: Tujuan penelitian ini adalah untuk mengetahui kelayakan dan respon siswa terhadap multimedia interaktif berbasis android bermuatan kemampuan berpikir kritis pada materi mutasi. Jenis penelitian ini yaitu research and development (R and D), penelitian ini dikembangkan menggunakan model pengembangan ADDIE (Analysis, Design, Development, Implementation, Evaluation). Sampel pada penelitian ini yaitu 10 siswa MAN 2 Semarang. Hasil penelitian : ahli media sebesar 76 persen, ahli materi sebesar 81,81 persen, ahli berpikir kritis sebesar 90 persen, tanggapan guru sebesar 91,61 persen, dan hasil respon siswa terhadap aplikasi multimedia interaktif sebesar 92,66 persen. Berdasarkan hasil penelitian dapat disimpulkan bahwa multimedia interaktif berbasis android untuk melatih kemampuan berpikir kritis pada materi mutasu sangat layak digunakan sebagai bahan ajar. Kata kunci: keterampilan berpikir kritis, multimedia interaktif, penelitian pengembangan.DOI: http://dx.doi.org/10.23960/jpmipa/v23i3.pp824-832]]>
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