Berkala Ilmu Kesehatan Kulit dan Kelamin
Vol. 34 No. 3 (2022): DECEMBER

Pattern of Candida Species Isolated from Patient with Vulvovaginal Candidiasis in Pregnancy

Purnamasari, Indah (Unknown)
Ervianti, Evy (Unknown)
Damayanti, Damayanti (Unknown)
Budi Prasetyo (Unknown)
Astari, Linda (Unknown)
Pepy D. Endraswari (Unknown)
Listiawan, M. Yulianto (Unknown)
Cita Rosita Sigit Prakoeswa (Unknown)



Article Info

Publish Date
30 Nov 2022

Abstract

Background: Vulvovaginal candidiasis (VVC) is one of the most prevalent genital tract diseases in women. The identification of the isolated Candida species is critical for guiding empirical antifungal therapy. Purpose: To determine the Candida species that cause vulvovaginal candidiasis in pregnancy at the Obstetrics and Gynecology Outpatient Clinic, Dr. Soetomo General Academic Hospital, thus providing scientific and therapeutic benefits. Methods:  Pregnant woman receiving antenatal care (ANC) at Dr. Soetomo General Academic Hospital Obstetric and Gynecology Outpatient Clinic. Subjects were enrolled in a cross-sectional study during 3 months between March and May 2021. Vaginal swab samples were taken from subjects after informed consent. A specific color change in CHROMagar cultures and VITEK 2 compact were used to identify Candida species. Result: During the study period, 15 pregnant patients were diagnosed with VVC. The majority of the women in the study were pregnant women of sexually active age who complained of a whitish body and genital irritation. There were 18 candida isolates from CHROMagar cultures, with C. non albicans (61.1%) predominating over C. albicans (38.3%). With details, non albicans were C. glabrata (54.4%), C. dubliniensis (36.3%), and C. parapsilosis (18.1%). Conclusion: This study revealed a high prevalence of Candida non-albicans species causing VVC. Culture investigation and identification of Candida are critical to avoid diminished susceptibility to antifungal treatments and recurrence.

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