Majalah Farmaseutik
Vol 18, No 3 (2022)

Challenges and potentials of developing domperidone into the transdermal delivery

Sekar Ayu Pawestri (Universitas Gadjah Mada)
Akhmad Kharis Nugroho (Universitas Gadjah Mada)
Endang Lukitaningsih (Universitas Gadjah Mada)
Purwantiningsih Purwantiningsih (Universitas Gadjah Mada)



Article Info

Publish Date
10 Oct 2022

Abstract

Nausea, which often coexists with vomiting, is an uneasy sensation in the stomach caused by several factors. Oral domperidone is widely prescribed in nausea treatment. The low bioavailability of oral domperidone makes a patient take the drug more frequently, even though some patients have difficulty swallowing the drug when suffering nausea. Recently, the drug formulation development for transdermal delivery systems is expected to increase in the future. Practical and increase patient comfortable is the notable advantages of using transdermal dosage form. Domperidone is currently being studied into various pharmaceutical dosage forms with the transdermal route. This present article provides summaries of the constraints also the current formulation development of domperidone which shows the potential of domperidone in transdermal delivery.

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Journal Info

Abbrev

majalahfarmaseutik

Publisher

Subject

Medicine & Pharmacology

Description

Majalah Farmaseutic accepts submission concerning in particular fields such as pharmaceutics, pharmaceutical biology, pharmaceutical chemistry, pharmacology, and social ...