Indonesian Journal of Chemistry
Vol 23, No 3 (2023)

Synthesis of Hydroxyapatite-Polyethylene Glycol with In-Situ Method Using Calcium Oxide from Blood Shells (Anadara granosa)

Novesar Jamarun (Department of Chemistry, Andalas University, Limau Manis, Padang 25163, Indonesia)
Nabiila Ayyu Trycahyani (Department of Chemistry, Andalas University, Limau Manis, Padang 25163, Indonesia)
Syukri Arief (Department of Chemistry, Andalas University, Limau Manis, Padang 25163, Indonesia)
Upita Septiani (Department of Chemistry, Andalas University, Limau Manis, Padang 25163, Indonesia)
Vivi Sisca (Department of Biology Education, Institute of Education YPM Bangko, Jl. Jenderal Sudirman, Meranging, Jambi 37313, Indonesia)



Article Info

Publish Date
04 May 2023

Abstract

Hydroxyapatite (Ca10(PO4)6(OH)2, HAp) is a calcium phosphate-based biomaterial that is widely used in bone implants due to its similarity in composition with the constituent elements of bone. However, HAp still has poor mechanical properties, so research was carried out to improve the mechanical properties such as reduced brittleness, less fracture resistance, and a denser structure of HAp by synthesizing composites with PEG. This study used PEG as a filler and HAp as a matrix. HAp was synthesized from blood clam shells (Anadara granosa) using the sol-gel method. HAp-PEG composite was synthesized using the in-situ method with various HAp concentrations of 40, 50, 60, 70, and 80%. FTIR characterization showed the presence of functional groups PO43− and CO23−, which indicated the presence of HAp. Analysis of the XRD pattern showed a crystal size of 24.194 nm. SEM-EDX showed the needle-shaped HAp-PEG composite HAp crystal morphology and obtained a Ca/P ratio of 1.87. Analysis of DTA results showed a weight loss of 65.72% in the composite at a temperature > 200 °C. A degradation test was also carried out to see the percentage of the HAp-PEG composite to be degraded, and the optimum degraded composite with increasing days had a concentration of 70%.

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Journal Info

Abbrev

ijc

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology ...