Journal of Pharmaceutical and Sciences.
JPS Volume 6 Nomor 3 (2023)

Uji Efektivitas Ekstrak Etanol Daun Labu Siam (Sechium edule (Jacq.) Swartz) Sebagai Penyembuh Luka Sayat pada Tikus Putih (Rattus norvegicus)

Charly J. Watung (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon)
Christel N. Sambou (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon)
Jabes W. Kanter (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon)
Reky R. Palandi (Program Studi Biologi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon.)

Article Info

Publish Date
11 Jul 2023

Abstract

Herbal plants refer to plant species that can be used as medicinal herbs, either individually or in combinations, believed to prevent and facilitate wound healing. One such herbal plant commonly used by the community is the leaves of Chayote (Sechium edule (Jacq.) Swartz), believed to accelerate the healing of wounds. This research aims to determine the effectiveness of ethanol extract from Chayote leaves (Sechium edule (Jacq.) Swartz) in healing incision wounds in white rats (Rattus norvegicus). The samples used were 15 male rats. A 1 cm incision wound was made on the rats' backs using a surgical blade. The research employed a Completely Randomized Design (CRD) with 5 treatments: negative control, positive control (10% povidone iodine), and 3 concentrated extracts (5%, 10%, 15%) with 3 repetitions each. The treatments were administered twice a day for seven days. The calculation of wound healing percentage in rats based on the research results indicated that Chayote leaf extract with a concentration of 15% showed 100% effectiveness in healing incision wounds in white rats.

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Journal Info
Journal of Pharmaceutical and Sciences.
Website

Abbrev

jps

Publisher

Universitas Tjut Nyak Dhien

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...