IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)
Vol 8, No 3 (2023): October 2023

Antibacterial Activity of Triterpenoid from The Leaves of Tahi Ayam (Lantana camara Linn)

Kartika MZ (Department of Chemistry Faculty of Mathematics and Natural Sciences Universitas Syiah Kuala Darussalam Banda Aceh 23111, Indonesia)
Suryati Suryati (Department of Chemistry Faculty of Mathematics and Natural Sciences Universitas Andalas, Kampus Limau Manis, Padang 25163, West Sumatra, Indonesia)
Mai Efdi (2. Department of Chemistry Faculty of Mathematics and Natural Sciences Universitas Andalas, Kampus Limau Manis, Padang 25163, West Sumatra, Indonesia)



Article Info

Publish Date
06 Oct 2023

Abstract

Tahi Ayam (Lantana camara Linn) is known as the herbal plant to cure several diseases and has been used in folk medicine. The result of this study indicates that the isolated compound and the ethyl acetate fraction are components having antibacterial activity. The isolated compound from the ethyl acetate fraction from the leaves of the Lantana camara Linn plant is 9-hydroxy-Lantadene A. The compound includes the triterpenoid compound group, the molecular formula is C35H52O6, and another name is 22-angeloiloxy-9-hydroxy-3-oxo-olean-12-en-28-oat. The antibacterial activity of this compound was determined by looking at the inhibition zone of the test bacteria, namely Staphylococcus aureus as gram-positive and Escherichia coli as gram-negative. The treatment has been using the disc diffusion method and using amoxicillin as a control positive. The result of the antibacterial activity test revealed that both 9-hydroxy-Lantadene A and the ethyl acetate fraction exhibited antibacterial activity. Becouse there are inhibition zones around the discs at concentrations of 10 μg/disk and 5 μg/disk.

Copyrights © 2023






Journal Info

Abbrev

IJFAC

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science

Description

Indonesian Journal of Fundamental and Applied Chemistry (IJFAC) is an international research journal and invites contributions of original research articles as well as review articles in several areas of chemistry. The journal aims to publish refereed, high-quality research papers with significant ...