Journal of Pharmaceutical and Sciences.
JPS Volume 6 Nomor 4 (2023)

Uji aktivitas antibakteri kombinasi ekstrak kulit dan biji Pepaya (Carica papaya L.) terhadap bakteri Staphylococcus aureus dan Escherichia coli

Indra Ginting (Program Studi Farmasi, Fakultas Farmasi dan Kesehatan, Institut Kesehatan Helvetia, Medan, Sumatera Utara, Indonesia.)
Singgar Ni Rudang (Program Studi Farmasi, Fakultas Farmasi, Universitas Sumatera Utara, Medan, Sumatera Utara, Indonesia.)
Muhammad Andry (a:1:{s:5:"en_US"
s:27:"Institut Kesehatan Helvetia"
})
Mayang Sari (Program Studi Farmasi, Fakultas Farmasi dan Kesehatan, Institut Kesehatan Helvetia, Medan, Sumatera Utara, Indonesia.)
Muhammad Amin Nasution (Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Al-Washliyah, Medan, Sumatera Utara, Indonesia.)

Article Info

Publish Date
19 Oct 2023

Abstract

Background;; Infectious diseases suffered by many people include Enterobacter infection from E.coli and skin infections due to S. aureus. One of the plants that have antibacterial properties is papaya like seeds and skin. Objekctives; The purpose of this study was to determine the activity of papaya skin and Seed (Carica papaya L.) extracts against S. aureus and E.coli. Method; The study used experimental method. The extraction used was maceration with ethanol 80%, 60% solvent. 40% and 20%. Antibacterial Activity Test using disc diffusion method and phytochemical screening test on papaya skin extract (Carica papaya L). Result; The results of screening tests on papaya skin extract (Carica papaya L) were positive for alkaloids, saponins, tannins, flavonoids and steroids. The results obtained at 60% ethanol showed that the combined extract of papaya skin and seeds (Carica papaya L) on S. aureus with concentrations (20:80) - (80:20) was 11.9 mm - 15.6 mm. In E. coli with a concentration (20:80) - (80:20) of 9.7 mm - 14.9 mm. Conclusion; The conclusions from the results of research on the combination of papaya skin and papaya seeds (Carica papaya L) of various concentrations inhibited S.aureus bacteria more than E.coli bacteria.

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Journal Info
Journal of Pharmaceutical and Sciences.
Website

Abbrev

jps

Publisher

Universitas Tjut Nyak Dhien

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...