Scientific Journal of Pediatrics
Vol. 1 No. 2 (2023): Scientific Journal of Pediatrics

The Role of Chronic Inflammation in Stunting: A Systematic Literature Review

Daniella Thomas (Faculty of Public Health, Duke University, Durham, US)
Sing Way (Faculty of Public Health, Duke University, Durham, US)



Article Info

Publish Date
17 Nov 2023

Abstract

Chronic inflammation can overactivate the body's immune system, causing excessive release of cytokines and inflammatory substances. This can affect the balance between the inflammatory response and the immune response, so that the immune system may be more focused on fighting inflammation rather than protecting the body from infection. Chronic inflammation can disrupt the body's growth pathways. Some molecules involved in the growth process, such as growth hormone, can be disrupted by inflammation. Additionally, inflammation can affect the development of the body's organs, tissues, and cells in ways that inhibit linear growth. This study aims to explore the role of chronic inflammation in the incidence of stunting. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the role of chronic inflammation in the incidence of stunting. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Chronic inflammation plays an important role in the occurrence of stunting in children. Chronic inflammation can influence various aspects that contribute to the growth and development of children's bodies, including nutrient absorption, growth hormone regulation, nutrient metabolism, and immune system function. This can result in stunted child growth, malnutrition, weight loss, and negative impacts on child well-being.

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Journal Info

Abbrev

sjped

Publisher

Subject

Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Description

Focus Scientific Journal of Pediatrics (SJPed) focused on the development of medical sciences especially pediatrics and child health for human well-being. Scope Scientific Journal of Pediatrics (SJPed) publishes articles which encompass all aspects of basic research/clinical studies related to the ...