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Patricia Wulandari
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INDONESIA
Scientific Journal of Pediatrics
Published by Phlox Institute: Indonesian Medical Research Organization
ISSN : 30256224     EISSN : 30256224     DOI : https://doi.org/10.59345/sjped
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Focus Scientific Journal of Pediatrics (SJPed) focused on the development of medical sciences especially pediatrics and child health for human well-being. Scope Scientific Journal of Pediatrics (SJPed) publishes articles which encompass all aspects of basic research/clinical studies related to the field of pediatrics and allied science fields, especially all type of original articles, case reports, review articles, narrative review, meta-analysis, systematic review, mini-reviews and book review.
Arjuna Subject : Kedokteran - Pediatrics, Perinatology, and Child Health
Articles 10 Documents
 1 
The Relationship between Feeding Patterns and Stunting Incidence in Toddlers Aged 12-59 Months in the Working Area of Pembina Health Center, Plaju, Palembang, Indonesia Rachmat Hidayat
Scientific Journal of Pediatrics Vol. 1 No. 1 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i1.11

Abstract

Introduction: Stunting is a linear growth disorder caused by malnutrition and chronic infectious diseases. The food intake of a child is very highly influenced by parental feeding patterns. The more optimal the feeding of a child, of course, the more optimal the growth and development of the child, where the factor of nutrition greatly affects the growth of a child's body. This study aimed to determine the relationship between feeding patterns and the incidence of stunting in toddlers aged 12-59 months in the working area of Pembina Health Center, Plaju, Palembang, Indonesia. Methods: This study is a cross-sectional analytic observational study. A total of 100 research subjects participated in this study. Analysis of sociodemographic data and feeding patterns was carried out using SPSS software univariate and bivariate. Results: The study results show that the majority of the subject with poor feeding patterns have a greater proportion of stunting events. Meanwhile, research subjects with good feeding patterns had a smaller proportion of stunting events. The results of this study indicate that the pattern of feeding in children is related to the incidence of stunting, p<0.05. Conclusion: The pattern of feeding children is related to the incidence of stunting in toddlers aged 12-59 months in the working area of Pembina Health Center, Plaju, Palembang, Indonesia.
Changes in Sexual Maturity (Puberty): A Narrative Literature Review Rizki Ayu
Scientific Journal of Pediatrics Vol. 1 No. 1 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i1.12

Abstract

The process of sexual maturation, or puberty, is marked by the development of secondary sexual characteristics, rapid body growth, and, ultimately, the ability to reproduce. Various congenital and endocrine disorders can interfere with the timing of sexual maturation, causing delayed puberty or precocious puberty. This literature review aimed to describe puberty and its disorders and influencing factors. The age of puberty is multifactorial, involving genetic and environmental components. Delayed puberty is a physiological (constitutional) delay in which hormonal levels are normal, and the hypothalamic-pituitary-gonadal (HPG) axis is intact, but maturation occurs slowly. Precocious puberty can be partial, complete, or mixed type and can be further categorized into central (GnRH dependent) and peripheral (GnRH dependent). In conclusion, congenital and endocrine disorders can interfere with the timing of sexual maturation, causing delayed puberty or precocious puberty.
Overview of Clinical Symptoms of Pediatric Patients Infected with Coronavirus Disease 2019 (COVID-19) at Dr. M Djamil General Hospital, Padang, Indonesia Akhirul Bari
Scientific Journal of Pediatrics Vol. 1 No. 1 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i1.13

Abstract

Introduction: COVID-19 is a disease caused by infection with a new coronavirus with the name SARS-CoV-2 and can be transmitted between humans. Transmission of COVID-19 occurs through droplets produced by infected people. Indonesia is a country affected by COVID-19, with cases reaching 2,203,108 cases. The number of cases in Indonesia also includes COVID-19 infections in children. This study aimed to present an overview of the clinical symptoms of pediatric patients infected with coronavirus disease 2019 at Dr. M Djamil General Hospital, Padang, Indonesia. Methods: This study is a descriptive observational study. A total of 50 research subjects participated in this study. Observations of sociodemographic data and observations of clinical data were carried out in this study. Univariate data analysis was performed to present the distribution of frequencies and percentages of each variable. Results: The majority of clinical symptoms of pediatric COVID-19 patients are fever. Apart from fever symptoms, the majority of clinical symptoms of child COVID-19 patients have symptoms of runny nose, shortness of breath, nausea and vomiting, and diarrhea. Conclusion: Fever is a clinical symptom of the 2019 coronavirus disease (COVID-19) infection in children at Dr. M Djamil General Hospital, Padang, Indonesia.
Overview of Hirschsprung Disease: A Narrative Literature Review Harsani Lampus
Scientific Journal of Pediatrics Vol. 1 No. 1 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i1.14

Abstract

Hirschsprung disease is a congenital malformation resulting from the failure of neural crest cells to migrate into the gastrointestinal tract. The exact cause of this disorder is unknown, but it is suspected that there is an interaction of several factors, including gene mutations and epigenetic mechanisms. This literature review aimed to describe the pathophysiology, clinical symptoms, and treatment of Hirschprung disease. Mild to severe constipation is a common manifestation of Hirschsprung's disease with poor diet, poor weight gain, and progressive abdominal distention. However, diarrhea may be the first sign, as only water can flow around the affected stool. The most serious complication in the neonatal period is Hirschsprung-associated enterocolitis (HAEC), which can occur both preoperatively and postoperatively. Surgery is the definitive treatment in all cases of Hirschsprung's disease, with resection of the aganglionic segment and anastomosis of the bowel proximal to the anus, known as a pull-through procedure. In conclusion, Hirschsprung disease is a congenital aganglionic megacolon or functional obstruction of the large intestine and is caused by multifactorial factors, especially the role of genetic aspects.
Acute Rheumatic Fever and Rheumatic Heart Disease: Narrative Literature Review Bagus Winandi Arundito; Teti Adriana Lubis
Scientific Journal of Pediatrics Vol. 1 No. 1 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i1.15

Abstract

Rheumatic fever is a systemic inflammatory disease caused by an immune and inflammatory response to infection by group A beta-hemolytic streptococci in individuals with a genetic predisposition. In its acute form, rheumatic fever is a febrile illness that occurs about 2 to 3 weeks after infection and is characterized by inflammation of the joints, skin, nervous system, and heart. If left untreated, rheumatic fever can lead to scarring and structural deformities of the heart resulting in rheumatic heart disease (RHD). This literature review aimed to describe acute rheumatic fever and rheumatic heart disease in children. Therapy for acute rheumatic fever is aimed at eradicating streptococcal infection regimen 10 days of antibiotics NSAIDs are used as agent anti-inflammatory for rheumatic carditis and arthritis and help relieve symptoms, but does not prevent complications. Serious carditis may require diuretics and vasodilators, and recovery may take up to 12 months. Damaged valve repair surgery may be necessary in cases of recurrent chronic rheumatic fever or carditis. In conclusion, rheumatic fever is a systemic inflammatory disease caused by an immune and inflammatory response to infection by group A beta-hemolytic streptococci in individuals with a genetic predisposition. If left untreated, rheumatic fever can lead to scarring and structural deformities of the heart resulting in rheumatic heart disease (RHD).
Nephrotic Syndrome in Pediatrics: A Case Report Ratu Hanny Anggorowati; Huminsa Ranto Mourison Panjaitan; Andre Yusanto; Rati Annisah
Scientific Journal of Pediatrics Vol. 1 No. 2 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i2.46

Abstract

Introduction: The prevalence of childhood NS worldwide is approximately 16 cases per 100,000 children, with an incidence of two to seven per 100,000 children. Primary causes of NS include minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, genetic disorders, and secondary diseases associated with infections, drugs, and neoplasia; however, it can also be idiopathic. Case presentation: A 14-year-old male toddler weighing 39 kg with a 1-week history of swelling around the eyes and both legs and generalized body swelling. On physical examination, swelling was found in both lower legs (pitting type). Laboratory investigations showed protein in urine and reduced serum albumin (2.0 g/dL) with elevated lipid levels. Although a kidney biopsy could not be performed due to the economic problem of the family, a diagnosis of idiopathic nephrotic syndrome (NS) was made based on clinical and laboratory findings. Conclusion: Nephrotic syndrome in children includes dietary adjustments, administration of diuretics to reduce edema, and administration of immunosuppressants such as steroids to induce remission.
Factors Playing a Role in Early Initiation of Breastfeeding Noor Istiqomah; Rizki Amalia
Scientific Journal of Pediatrics Vol. 1 No. 2 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i2.65

Abstract

Factors influencing early initiation of breastfeeding are of great importance in the understanding and practice of maternal and neonatal care. Mothers' knowledge about the importance of early initiation of breastfeeding, support from health workers, health service policies, and various other aspects play a key role in the success of this practice. In the context of early breastfeeding initiation, many elements work together, including education, the care environment, and social support, all of which contribute to helping mothers achieve success in breastfeeding their babies well. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding factors that play a role in early initiation of breastfeeding. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Early initiation of breastfeeding is an important practice in maternal and neonatal care that has great benefits for both baby and mother. Maternal education about the benefits of early initiation of breastfeeding and support from health workers play a key role in increasing awareness and understanding. The availability of medical facilities that support this practice, including baby-friendly delivery rooms and well-trained medical teams, is another very important factor. In addition, early interactions between mother and baby, such as skin-to-skin contact and bringing the baby closer to the mother's breast, also play a crucial role in stimulating early initiation of breastfeeding. Support from the mother's family and environment, together with shared commitment, is very important in creating an environment that supports this practice.
The Role of Molecular Aspects in the Occurrence of Febrile Seizures Septiana Sari; Santi Dwi Yuliana
Scientific Journal of Pediatrics Vol. 1 No. 2 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i2.66

Abstract

Febrile seizures are the result of complex interactions between multiple molecular components in the child's central nervous system, including changes in neurotransmitters, neuronal activity, and the brain's inflammatory response. When a child has a fever, there is an increase in body temperature, which triggers a series of molecular changes in the brain, affecting electrical signaling pathways and triggering characteristic seizures. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding studies of molecular aspects of febrile seizures. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. An increase in body temperature (fever) is the main trigger for febrile seizures. Fever can result in changes in brain chemistry, including changes in neurotransmitters and inflammatory responses, which can affect the molecular pathways that trigger seizures. Glutamate is the main neurotransmitter that plays a role in triggering seizures. Increased glutamate release during fever can trigger excessive activity in neurons. On the other hand, GABA, a neurotransmitter that plays a role in dampening neuronal activity, may also be involved, and an imbalance between glutamate and GABA may occur during seizures. Genetic factors play a role in susceptibility to febrile seizures. Several genes, such as SCN1A and GABRG2, have been identified as potentially increasing the risk of febrile seizures, especially those of a complex nature. Febrile seizures usually do not cause permanent changes in brain structure. However, in some very rare cases, such as EASIFE, temporary changes in brain structure may occur.
Study of Pathophysiological Aspects of Acute Diarrhea Due to Rotavirus Infection Ardina Permatasari; Muhammad Ilhamsyah
Scientific Journal of Pediatrics Vol. 1 No. 2 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i2.67

Abstract

Rotavirus is a highly contagious virus that enters the body through the consumption of food or water contaminated by the feces of an infected individual. After entering the body, rotavirus infects the epithelial cells lining the small intestine, which is the main site for the absorption of nutrients and water. Rotavirus infects intestinal epithelial cells by attaching to the cell surface and entering the cell. This triggers changes in the epithelial cells, including changes in the receptors present on the surface of the cells. Viruses damage epithelial cells by remodeling the cell's cytoskeleton. This causes epithelial cells to lose their ability to absorb nutrients and water properly. Over time, damage to these epithelial cells causes increased intestinal leakage, allowing fluid to enter the intestines faster than it can be absorbed. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding studies of the pathophysiology of acute diarrhea due to Rotavirus infection. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Rotavirus causes damage to intestinal epithelial cells by remodeling the cell cytoskeleton. This results in epithelial cells losing their ability to absorb nutrients and water properly. Rotavirus infection triggers inflammation in the intestines. Infected cells release inflammatory mediators, such as cytokines, which trigger response inflammation. This inflammation causes intestinal irritation, increased bowel movements, and increased mucus production. Fluid loss through diarrhea is a major consequence of rotavirus infection. Babies and children, especially, are especially susceptible to serious dehydration. Dehydration can be life-threatening if not treated quickly and efficiently.
The Role of Chronic Inflammation in Stunting: A Systematic Literature Review Daniella Thomas; Sing Way
Scientific Journal of Pediatrics Vol. 1 No. 2 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i2.68

Abstract

Chronic inflammation can overactivate the body's immune system, causing excessive release of cytokines and inflammatory substances. This can affect the balance between the inflammatory response and the immune response, so that the immune system may be more focused on fighting inflammation rather than protecting the body from infection. Chronic inflammation can disrupt the body's growth pathways. Some molecules involved in the growth process, such as growth hormone, can be disrupted by inflammation. Additionally, inflammation can affect the development of the body's organs, tissues, and cells in ways that inhibit linear growth. This study aims to explore the role of chronic inflammation in the incidence of stunting. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the role of chronic inflammation in the incidence of stunting. This study follows the preferred reporting items for systematic reviews and meta-analysis (PRISMA) recommendations. Chronic inflammation plays an important role in the occurrence of stunting in children. Chronic inflammation can influence various aspects that contribute to the growth and development of children's bodies, including nutrient absorption, growth hormone regulation, nutrient metabolism, and immune system function. This can result in stunted child growth, malnutrition, weight loss, and negative impacts on child well-being.

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