Indonesian Journal of Science and Pharmacy
Vol. 1 No. 3 (2024): Indonesian Journal of Science and Pharmacy

Antibacterial Activity Of Freshwater Lobster Shells (Cherax quadricarinatus) Against Escherichia coli

Putri Hafizha (Department of Pharmacy, Faculty of Pharmacy, Universitas Muslim Nusantara Al-Washliyah)
Ridwanto Ridwanto (Department of Pharmacy, Faculty of Pharmacy, Universitas Muslim Nusantara Al-Washliyah)
Anny Sartika Daulay (Department of Pharmacy, Faculty of Pharmacy, Universitas Muslim Nusantara Al-Washliyah)
Haris Munandar Nasution (Department of Pharmacy, Faculty of Pharmacy, Universitas Muslim Nusantara Al-Washliyah)



Article Info

Publish Date
30 Apr 2024

Abstract

People still do not utilize freshwater lobster (Cherax quadricarinatus) shells optimally, even though the chitin compound contained in this waste can be modified into chitosan through chemical reactions. Chitosan obtained from freshwater lobster shells can be used as an antibacterial. This study aims to test the antibacterial activity of chitosan from freshwater lobster shell waste against Escherichia coli bacteria. Making chitosan is carried out through three processes, namely, demineralization, deproteination, and deacetylation stages. Then, characterization of the chitosan is carried out, which includes water content, ash content, yield, and solubility. The research results showed that the chitosan obtained in this study was 43.96%, and the degree of deacetylation value of freshwater lobster shell chitosan was 75.11%. Chitosan with a concentration of 0.3, 0.5, 0.7, and 0.9% provides an inhibition zone of 13.5, 15.9, 16.8, and 17.2 mm, respectively, against Escherichia coli. Thus, a concentration of 0.9% chitosan from freshwater lobster shells has better antibacterial activity and is categorized as having strong inhibitory power.

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Journal Info

Abbrev

IJSP

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

Indonesian Journal of Science and Pharmacy (IJSP) accepts scientific articles as original research articles, short communication, reviews, and mini-reviews from anyone without any discrimination, as long as they submit articles that meet scientific principles. Indonesian Journal of Science and ...