Multidiciplinary Output Research for Actual and International Issue (Morfai Journal)
Vol. 4 No. 2 (2024): July

MALONDIALDEHIDE (MDA) URINE AS AN EARLY MARKER OF DEVELOPMENTAL DISORDERS OF CHILDREN LIVING AROUND GOLD MINES

Ernawati (Universitas Teuku Umar)
Adi Heru Sutomo (Universitas Gadjah Mada)
Indwiani Astuti (Universitas Gadjah Mada)
Enda Silvia Putri (Universitas Teuku Umar)
Marniati (Universitas Teuku Umar)
Itza Mulyani (Universitas Teuku Umar)
Sufyan Anwar (Universitas Teuku Umar)
Eva Flourentina Kusumawardani (Universitas Teuku Umar)
Suci Eka Putri (Universitas Teuku Umar)
Hasanuddin Husin (Universitas Teuku Umar)

Article Info

Publish Date
09 Jul 2024

Abstract

Children born to mothers living around gold mines are at risk of mercury exposure (Hg) and can cause developmental disorders. These developmental disorders can be detected early through stress oxidation mechanisms based on Hg toxicity that directly harm brain cells. It can be detected early on from the level of DNA damage, which is malondialdehyde (MDA) in the urine. Examining children's MDA urine levels near gold mines is the aim of this study. The Observational Research Method performs measurement of MDA of baby urine with TBARS examination of 16 babies in the age range of 2-14 weeks babies who live around the gold mining village Kalirejo Prefecture Kokap district of Kulon Progo Yogyakarta. The result was a rate of 3.23 μmol/L of MDA in baby urine, which is above the normal level of 1.03 μMol/L. So it can be concluded that the high level of MDI in the baby's urine is an early indication of a child's developmental disorder living around the gold mining.

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Journal Info
Multidiciplinary Output Research for Actual and International Issue (Morfai Journal)
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Abbrev

MORFAI

Publisher

CV. RADJA PUBLIKA

Subject

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Social Sciences Other

Description

MORFAI This journal will publish research articles or studies that are multidisciplinary in nature, including: education, law, health, agriculture, engineering, energy, technology, and social science. This journal is dedicated to explore and socialize many creative and innovative thought who focus ...