Berkala Kedokteran
Vol 11, No 2 (2015): September 2015

POTENSI BUAH NANGKA (Artocarpus heterophyllus L) SEBAGAI ANTIDIABETES IN VITRO

Khairina, Khairina (Unknown)
Suhartono, Eko (Unknown)
Biworo, Agung (Unknown)



Article Info

Publish Date
12 Feb 2016

Abstract

Artocarpus species have been used by traditional medicine of Indonesian. It can be useful as anti-bacterial, anti-diabetic, anti-inflammatory, antioxidant and anti-helmintics. The present study was aimed to test the inhibitory glycated hemoglobin potency of aqueous extract of Jackfuit. This study is a quasi experimental research with non randomized method post test-only group design, which using a model reaction of two groups : extract jackfruit as the test group and glikazid as the control group, with each concentration of 10%, 20%, 30%. Potential inhibitor of glycated hemoglobin jackfruit as determining the amount of IC50. From this research  got IC50 of jackfruit extracts is 56,43% (r=0,999) whereas for glikazid of 17.268 (r = 0.989). The value of r indicates a positive relationship between the concentration and the inhibitor glycated hemoglobin potential. These results indicate that the extract of Jackfruit has potential as an inhibitor glycated hemoglobin. Keywords: glycated hemoglobin,  jackfruit, Artocarpus heterophllus L, glikazid.

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Journal Info

Abbrev

jbk

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and ...