<![CDATA[Abstract Integrated malaria vector control study has been conducted in the border area of Indonesia-Malaysia, Sebatik Island, Nunukan Regency, Kalimantan Timur Province. The objective of the study was to determine the impact of integrated vector control application against quantitative entomological indicators as malaria epidemiology variable. The evaluation was carried out by all night human landing mosquito collection and larval density (dipper method; 350 ml volume) calculated as number of larvae per dip. The study revealed two mosquito species Anopheles balabacensis and Anopheles maculatus as malaria vectors in the area. Anopheles balabacensis was found predominant, highly antrophophylic 88,33% and the sporozoite index which was determined by ELISA test 12,75%. Quantitative entomological indicators such as: vectorial capacity, entomological inoculation rate, stability index of An. balabacensis as malaria vector and the malaria cases were found gradualy decreased and within 6 months evaluation, 100% reductions were occured. Results of this study indicated the effectiveness of vector control application. Integrated vector control method is recommended to be applied in effort to maintained low malaria endemicity and not to be applied during the outbreak. Keywords: Malaria, Integrated control, Entomologycal indicator, Sebatik Island Abstrak ARTIKEL Telah dilakukan penelitian pengendalian vektor malaria terpadu di daerah lintas batas Indonesia-Malaysia, Pulau Sebatik (Dusun Berjoko/Lordes, Desa Sungai Limau), Kabupaten Nunukan, Provinsi Kalimantan Timur, tahun 2011. Tujuan penelitian mengetahui efektivitas pengendalian vektor malaria terpadu, distribusi kelambu berinsektisida dan aplikasi biolarvasida (piriproksifen 0,5%) dengan metode evaluasi indikator entomologi kuantitatif, sebagai variabel epidemiologi malaria. Pengendalian dengan distribusi kelambu berinsektisida Long Lasting Insecticide Net (deltametrin 55 mg/m2), 1-2 unit/keluarga dan aplikasi bio-larvasida zat pengatur tumbuh (insect growth regulator) piriproksifen 0,5% di tempat perkembangbiakan nyamuk vektor dengan konsentrasi 1g/m2, setiap 2 minggu sekali. Evaluasi dilakukan dengan penangkapan nyamuk dan koleksi jentik (metode diper 350 ml). Ditentukan kepadatan jentik (ekor/ciduk) dan penurunan indikator entomologi kuantitatif sebagai variabel epidemiologi yaitu: kapasitas vektorial, rerata laju inokulasi entomologi, indek stabilitas nyamuk An. balabacensis sebagai vektor serta kasus malaria. Ditemukan 2 spesies nyamuk tersangka vektor malaria An. balabacensis dan An. maculatus, populasi An. balabacensis sangat dominan dan bersifat antropofilik 88,33% dengan sporozoit indek 12,75%. Setelah 6 bulan aplikasi pengendalian vektor malaria terpadu, indikator epidemiologi kuantitatif meliputi: kapasitas vektorial, rerata laju inokulasi entomologi, indek stabilitas An. balabacensis sebagai vektor dan kasus malaria menurun sampai 100%. Pengendalian vektor terpadu sangat efektif di daerah endemis untuk menjaga endemisitas malaria tetap rendah dan tidak direkomendasikan aplikasi pada waktu terjadi wabah dan peningkatan kasus. Kata kunci: Malaria, Pengendalian terpadu, Indikator entomologi, Pulau Sebatik]]>
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