JSFK (Jurnal Sains Farmasi & Klinis)
Vol 3, No 1 (2016): J Sains Farm Klin 3(1), November 2016

Pengaruh Ekstrak Etanol Daun Vernonia amygdalina, Del terhadap Kadar Kreatinin Serum Mencit Putih Jantan

Suryati Suryati (Fakultas Framasi Universitas Andalas)
Dwisari Dillasamola (Fakultas Framasi Universitas Andalas)
Fridhani Rahadiant (Akademi Farmasi Prayoga, Padang)

Article Info

Publish Date
28 Dec 2016

Abstract

Vernonia amygdalina, Del leaves which are locally known as Afrika Selatan leaves used as traditional medicine for diabetes, fever, hypertension and uric acid. A study on the effect of their ethanolic extract on serum creatinin level of male white mice has been done. A twenty of male white mice were divided into four groups which were control group and three test group (A, B, C) which given extract with dose 100 mg/kg BW, 200 mg/kgBW and 400 mg/kgBW respectively. Test group were given extract orally for 21 days. The mice neck was cut and their blood collected at 7th, 14th and 21st day. The serum creatinin level was measured by using spectrophotometer UV-Visible at 492 nm. The result showed all doses of ethanolic extract gave statistically difference on the serum creatinin level (p<0.05). The doses at 400 mg/kgBW showed the most effective in reducing serum creatinin level.

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Journal Info
JSFK (Jurnal Sains Farmasi & Klinis)
Website

Abbrev

jsfk

Publisher

Universitas Andalas

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Sains Farmasi & Klinis (J Sains Farm Klin) adalah jurnal ilmiah di bidang kefarmasian yang diterbitkan oleh Fakultas Farmasi Universitas Andalas bekerjasama dengan lembaga profesi "Ikatan Apoteker Indonesia" (IAI) daerah Sumatera Barat sejak tahun ...