ASEAN Journal on Science and Technology for Development
Vol. 35 No. 3 (2018): Developments in Nuclear Techniques in the Treatment of Cancer

Dose Analysis of In Vitro and In Vivo Test for Boron Neutron Capture Therapy (BNCT)

Hamidatul Faqqiyyah (Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang, Semarang 50229, Indonesia)
Sunarno Sunarno (Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang, Semarang 50229, Indonesia)
Isa Akhlis (Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang, Semarang 50229, Indonesia)
Yohannes Sardjono (Center of Accelerator Science and Technology, National Nuclear Energy Agency, Yogyakarta 55281, Indonesia)



Article Info

Publish Date
24 Dec 2018

Abstract

The purpose of this study was to determine the in vitro and in vivo doses of boron neutron capture cancer therapy (BNCT) using the SHIELD-HIT12A program. To be able to determine the recoil energy, the research was conducted using the Monte Carlo method. Running data obtained the value of ionization activity and recoil lost. The results showed that in vitro and in vivo doses of BNCT for soft tissue irradiation had a value of 0.312 × 10-2 Sv, which is safe and does not harm healthy body tissue around the cancer cells because it is below the threshold of 1.5 Rem or 15 × 10-3 Sv, in accordance with the provisions of the upper value permitted by the International Commission on Radiation Protection in 1966. While the comparative targets are water, the optimal target absorption dose was obtained at concentrations of 3.232 × 10-3 Gy. The dose of carbon equivalent in water with the type of thermal neutron radiation was 16.16 × 10-3 Sv; this dose is classified as unsafe.

Copyrights © 2018






Journal Info

Abbrev

ajstd

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Mathematics

Description

The coverage is focused on, but not limited to, the main areas of activity of ASEAN COST, namely: Biotechnology, Non-Conventional Energy Research, Materials Science and Technology, Marine Sciences, Meteorology and Geophysics, Food Science and Technology, Microelectronics and Information Technology, ...