cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Julius July
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota tangerang,
Banten
INDONESIA
Medicinus : Jurnal Kedokteran
  • Medicinus : Jurnal Kedokteran
  • Website
Published by Universitas Pelita Harapan
ISSN : 19783094     EISSN : 26226995     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Medicinus: Jurnal Kedokteran is an official journal of the Faculty of Medicine, Universitas Pelita Harapan launched in the year 2007. Medicinus is a peer-reviewed and open-access journal that covers basic, translational, or clinical aspects of health and medical science. Medicinus accepts original research articles, review articles, and also interesting case reports. Medicinus: Jurnal Kedokteran is published three times a year in February, June, and October.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue "Vol 7, No 5 (2019): February 2019 - May 2019" : 7 Documents clear
Pilot Study for Azoxymethane-induced Colon Cancer in Male Wistar Rats Riska Taufik; Abidin Pandianta; Rinaldy Kusuma; Imelda L. Winoto; Ivet Suriapranata; George Mathew
Medicinus Vol 7, No 5 (2019): February 2019 - May 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2469

Abstract

Introduction : The use of animal models could significantly further the elucidation of Colorectal Cancer (CRC) molecular pathogenesis and help in the discovery of preventive and therapeutic agents for the disease. Dimethylhydrazine (DMH) is a widely used chemical agent for Carcinogen induced CRC model. As agent, DMH is however becoming less readily available; hence in this Pilot Study we use Azoxymethane (AOM), a DMH metabolite as an alternative agent to induce CRC in male Wistar rats. Methods: Forty two male Wistar rats at six weeks of age were randomly assigned into negative control groups and groups receiving two AOM injections subcutaneously (SC) within one week interval at 15 mg/kg body weight (BW) and 20 mg/kg BW respectively. Rats were sacrificed 8, 16 and 24 weeks post- AOM administration. Aberrant crypt foci (ACF) were analyzed. Tumor foci were characterized by gross examination and histopathological characteristics. Results: All rats in the AOM groups developed tumors in the colonic mucosa. Formation of ACF was detected starting from 8 weeks post-AOM injection. The highest number of ACF with multiple crypts was observed at 16 weeks post-AOM administration. The total number of ACF did not vary between the two AOM doses. Mild, moderate and severe dysplastic cells were observed in colonic mucosa starting 8 weeks post-AOM injection. There was no statistically significant difference between number of severe dysplastic cells between the two AOM doses. Conclusion: Administration of AOM 15 mg/kg BW SC is able to induce CRC in male Wistar rats. Higher dose is not necessary since it does not result in higher tumor incidence. This cancer model may be utilized to study chemopreventive effect of various agents in the future.
Case Report : Generalized Myasthenia Gravis Devita Widjaja; Vivien Puspitasari
Medicinus Vol 7, No 5 (2019): February 2019 - May 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2497

Abstract

Generalized myasthenia gravis is a rare case of autoimmune wherein the antibodies destroy the post-sinaptic acetylcholine receptors at skeletal muscle’s neuromuscular junctions. The clinical presentation is specific distributin of motoric deficit without sensoric deficit which diminished with rest and worsens with excessive use. We report a case of a woman 52 yo with symptoms of ptosis, diplopia and dificulty of swallowing. Repetitive nerve stimulation showed >10% decrement and prostigmin test was positive. The patient was treated and showed clinical improvement.
Risk Factors of Cervical Cancer in Outpatient and Inpatient at Obstetric and Gynecology RSUP Dr. Mohammad Hoesin Palembang Monica Trifitriana; Rizal Sanif; Syarif Husin; Rido Mulawarman
Medicinus Vol 7, No 5 (2019): February 2019 - May 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2470

Abstract

 Introduction: Cervical cancer is a malignant tumor originating from primary squamous epithelial cells and it is one of the several types of cancers that affects more to women. Methods: This research uses descriptive analytic with case- control. The sample was 52 patients who divided into 26 patients with cervical cancer and 26 patients with non - cervical cancer were outpatient and inpatient at Department of Obstetrics and Gynecology Hospital Dr. Mohammad Hoesin Palembang during the period September 2016 -November 2016. This study uses primary data in the form of interviews. Data was analyzed by univariate and presented in a frequency distribution table. Furthermore, using bivariate analysis to determine the relationship and OR. Result: From 8 risk factors studied, there is sygnificancy correlation between pathological vaginal discharge (p= 0,0005 OR= ∞), parity (p= 0,0005 OR= 22,7), age (p= 0,0005 OR= 19,2), oral contraception usage for a long time (p= 0,0005, OR= 12,4), age of the first intercourse (p= 0,006, OR= 6,1 ), and the husband’s occupation (p= 0,05 OR= 3,6) with the incidence of cervical cancer. While, there are two risk factors that don’t have a sygnificancy correlation between smoking (p= 1,0) and changing sexual partners (p= 1,0) with the incidence of cervical cancer. Conclusion: The results of this research identified  risk factors that significantly related to cervical cancer incidence was the age, the age of first sexual intercourse, parity, long-term oral contraceptive use, a history of vaginal discharge, and the husband's occupation.
Epidemiology of Traumatic Brain Injury in Neurosurgery Department of Tertiary Referral Hospital at North Sumatera, Indonesia Steven Tandean; Jeffrey Japardi; Fini Kollins; Michael Lumintang Loe
Medicinus Vol 7, No 5 (2019): February 2019 - May 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2471

Abstract

Introduction : Traumatic brain injury (TBI) is the most common problem that caused morbidity and mortality in the world. Epidemiology information of TBI is very important in understanding the causes and the risk factors of TBI, so that effective programs can be designed to prevent injury. This study purposed to provide overview of TBI pattern in tertiary referral hospital at North Sumatera with focus on epidemiological data of TBI pattern. Methods : The design of this study is a retrospective, and it is done in general hospital H. Adam Malik from June-December 2018 with sample from all patient with traumatic brain injury that admited in hospital. All medical records with diagnosis traumatic brain injury will be assessed for several variables as age, gender, etiology, severity, length of stay and outcome. Results : During the period of study, 118 patients with traumatic brain injury were admitted in neurosurgery ward. The highest TBI cases was occurs in male patients with range age between 18-35 years old, and caused by traffic accident. Most patients admitted to Emergency department with GCS 13-15 and epidural hematoma was the most common lesion found in head CT scan. Length of stay in this research mostly between 1-5 days,  and  the mortality rate is about 16.9%, which is dominated by severe head injury. Conclusions : Head injury mostly found in male with productive age, and traffic accident be the most common caused. Severe head injury still have quite high mortality rate.
Service Condition of Customer Service Inhealth Admision RSUP Dr. Mohammad Hoesin Palembang when Serves BPJS Patient in 2014 K M Dimas Alphiano; M Zulkarnain; Rizma Adlia Syakurah
Medicinus Vol 7, No 5 (2019): February 2019 - May 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2474

Abstract

Introduction : Health Service includes administrative service. In RSUP Dr. Mohammad Hoesin Palembang, it is implemented by Customer Service Inhealth Admision. To describe the service condition of Customer Service Inhealth Admision when serves BPJS patients in 2014 based on the quality of service which are reliability, responsiveness, emphaty, tangible, and assurance and how it actualized them, it is necessary in depth interview and observation in Customer Service Inhealth Admision RSUP Dr. Mohammad Hoesin Palembang.Method : This study used observation and in depth interview with respondents, which were chosen purposively. The data were then transcribed and analysed for themes using deductive content analysis.Result : Service condition of Customer Service Inhealth Admision RSUP Dr. Mohammad Hoesin Palembang in 2014 is the service condition which are reliable and responsive, making efforts to actualize emphaty, tangible, and assurance aspects when serves the patients either BPJS or general before they hospitalized in RSUP Dr. Mohammad Hoesin Palembang.Conclusion : Customer Service Inhealth Admision requires improvement, in particular the queue system for the patients who want to find their bed before they hospitalized. Employee of Customer Service Inhealth Admision should enhance their efforts to actualize emphaty and assurance aspects when serve the patients.
Surface Contamination Of Covid-19: How Long Can The Virus Last? Cuay Yusnianingsih; Shannon Marcella Evangelina
Medicinus Vol 7, No 5 (2019): February 2019 - May 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2468

Abstract

The novel coronavirus, which is now known as COVID-19, has caused a global pandemic. It is known that the main transmission routes of the novel coronavirus are through droplets, close human-to-human contact, and contact with inanimate surfaces contaminated by the virus. Thus, it is important to find out how long SARS-CoV-2 can remain viable on different surfaces. A study by van Doremalen et al. (2020) found that SARS-CoV-2 can remain viable for up to 72 hours on plastic and stainless steel surfaces, 4 hours on copper, and 24 hours on cardboard. Chin et al. (2020) reported that SARS-CoV-2 could persist on wood and cloth for 2 days, and could last for 4 days on glass and banknotes. These findings indicate that viral contamination of object surfaces is an important and dangerous factor in spread of disease, emphasizing the urgent need for prevention strategies against transmission of infection through contact with inanimate surfaces.
Case Report : Caecal Endometrios is Causing Acute Small Bowel Obstruction Freda S. Halim
Medicinus Vol 7, No 5 (2019): February 2019 - May 2019
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v7i5.2476

Abstract

Introduction: Endometriosis in bowel is rare condition, about 12% of endometriosis cases. Most of bowel endometriosis rising in the rectosigmoid (90% of bowel endometriosis). Incidence of caecal endometriosis is very low (<5% of bowel endometriosis) and almost never causing acute small bowel obstruction(0.1-0.7%). The aim of this paper is to show that although  bowel obstruction caused by caecal endometriosis is difficult to diagnose as it is rare, and may require laparotomy to make definite diagnosis, but it should be considered in infertile female patient. Case: 37 years old woman infertile woman with intestinal obstruction with pre-operative diagnosis total acute small bowel obstruction caused by right colonic mass, with sepsis as the complication. Before the acute small bowel obstruction she complained of chronic right lower quadrant pain with chronic constipation alternate with chronic diarrhea, symptoms that happened both in bowel endometriosis and colorectal malignancy. She also complained of  chronic pelvic pain and dysmenorrhea. She has been married for 10 years with no child. The patient was never diagnosed with endometriosis and never seek medical attention for the infertility and the chronic pelvic pain. The patient underwent Abdominal CT Scan, with result:  massive small bowel obstruction, and caecal mass that causing acute small bowel obstruction. Diagnosis of Acute small bowel obstruction due to right colonic mass was made and emergency exploratory laparotomy was performed the patient. Methods: During the laparotomy, mass at caecum and ileocaecal that causing massive small bowel obstruction was found and standard right hemicolectomy and temporary mucousfistula ileostomy was performed. Result: The patient recovered well, discharged on 7th day post op. The pathology examination showed  ectopic endometriosis lesions in caecum and ileocaecal valve. The histopathology also confirmed with the immunohistochemistry, in which positive ER, PR, CD 10 and CD7 was found the ileocaecal and caecal mass. In the second operation,  reanastomosis of the ileum was done 3 months after the first operation. The chronic pelvic pain is decreasing dramatically after the first and second operation. Conclusion: Although bowel obstruction caused by caecal endometriosis is an extremely rare cause of intestinal obstruction but it   should be considered as a cause in infertile female patient to reduce morbidity and mortality, to reduce stoma creation and to promote resection completeness.

Page 1 of 1 | Total Record : 7

 1 

Filter by Year

2020 2020


Reset
Filter By Issues
All Issue Vol 11, No 2 (2023): June 2023 - September 2023 Vol 11, No 1 (2023): February 2023 - May 2023 Vol 10, No 3 (2022): October 2022 - January 2023 Vol 10, No 2 (2022): June 2022 - September 2022 Vol 10, No 1 (2022): February 2022 - May 2022 Vol 9, No 3 (2021): October 2021-January 2022 Vol 9, No 3 (2021): October 2021 - January 2022 Vol 9, No 2 (2021): June 2021-September 2021 Vol 9, No 1 (2021): February 2021 - May 2021 Vol 8, No 3 (2020): October 2020 - January 2021 Vol 8, No 2 (2020): June 2020 - September 2020 Vol 8, No 1 (2020): February 2020 - May 2020 Vol 7, No 7 (2019): October 2019 - January 2020 Vol 7, No 6 (2019): June 2019 - September 2019 Vol 7, No 5 (2019): February 2019 - May 2019 Vol 7, No 4 (2018): October 2018 - January 2019 Vol 7, No 3 (2018): June 2018 - September 2018 Vol 7, No 2 (2018): February 2018 - May 2018 Vol 7, No 1 (2017): October 2017 - January 2018 Vol 6, No 3 (2017): June 2017 - September 2017 Vol 6, No 2 (2017): February 2017 - May 2017 Vol 6, No 1 (2016): October 2016 - January 2017 Vol 5, No 3 (2016): June 2016 - September 2016 Vol 5, No 2 (2016): February 2016 - May 2016 Vol 5, No 1 (2015): October 2015 - January 2016 Vol 4, No 9 (2015): June 2015 - September 2015 Vol 4, No 8 (2015): February 2015 - May 2015 Vol 8 (2018): November 2018 Supplement More Issue