MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan
Magna Medica is a medical journal of APKKM contains papers and scientific articles created as a form of realization Tridharma college. The journal is published every six months, April and October of three articles in the form of: - Research article - Case report - Literature review The scope of this journal is all the field of medicine such as: -Internal medicine (including Pulmonary medicine and cardiovascular medicine) -Surgery (including urology, orthopaedic and traumatologic, plastic surgery, neurosurgery) -Anesthesia and Emergency Medicine -Neurology -Dermatology -Obstetric and Gynecologic -Forensic and Medicolegal -Clinical Pathology -Anatomical Pathology -Psychiatric -Ophthalmology -Otolaryngology -Pediatric -Radiology -Microbiology and parasitology -Basic Science of Medicine (including biochemistry, physiology, anatomy and Histology) -Public health and Health Management
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<![CDATA[Efek Pemberian Kombinasi Siprofloksasin dan A-Mangostin Secara In Vitro Terhadap Eradikasi Uropatogen Escherichia Coli ]]>
<![CDATA[Maya Dian Rakhmawatie]]>;
<![CDATA[Afiana Rohmani]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.191-199
<![CDATA[Effect of In Vitro Combination of Ciprofloxacin and A-Mangostin on Eradication of Uropathogen Escherichia ColiBackground: The percentage of resistance Escherichia coli (E. coli) in patients with UTI to ciprofloxacin reached 73.04%. Various attempts to maximize the use of antibiotics have been done, including optimizing the parameters pharmacokinetics/pharmacodynamics (PK / PD) of each antibiotic. Another effort is needed to optimize the use of antibiotic treatment that has been available, one of which combines the use of compounds derived from herbs, eg active compounds a-mangostin.Objective: The purpose of this study is to find the effect of the combination of á-mangostin and ciprofloxacin on uropathogen E. coli (UPEC) eradication.Methods: This research was carried out by treating the bacteria uropathogenE. coli (UPEC) in vitro. Treatment is divided into (a) treatment groups using ciprofloxacin concentration Cmax at 500 mg dose (2,4 μg/mL), (b) treatment groups using ciprofloxacin concentration Cmax at 750 mg dose (4,3 μg/mL), (c) treatment groups using ciprofloxacin concentration 2,4 μg/mL and a-mangostin concentration 0,18 μg/mL, (d) treatment groups using ciprofloxacin concentration 4,3 μg/mL and a-mangostin concentration 0,18 μg/mL.Result: states that a combination of á-mangostin and ciprofloxacin can prevent the growth of uropathogen E. coli ciprofloxacin-resistant strains (MIC value of 128 μg/mL) compared to administration of ciprofloxacin alone, but the effect was not significant. On uropathogen E coli sensitive to ciprofloxacin (MIC 0,008 μg/mL) and intermediate (MIC 0,5 μg/mL), there was no difference effect of decreasing the number of colonies between awarding a combination of ciprofloxacin and á-mangostin compared administering ciprofloxacin only.Conclusion: Provision of á-mangostin grading 0,18 μg/mL combined with ciprofloxacin had no real benefit in eradicating uropathogen E. coli, which is tested in vitro.]]>
<![CDATA[Hubungan Antara Cell Death Dengan Vaskularisasi Dan Reaksi Limfosit Pada Kanker Serviks Jenis Squamous Cell Carcinoma ]]>
<![CDATA[Bramantyas Kusuma Hapsari]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.112-116
<![CDATA[The Relationship Between Cell Death With Vascularization And Lymphocyte Reaction In Cervical Cancer Types Of Squamous Cell CarcinomaLatar Belakang: Kanker serviks merupakan masalah kesehatan yang menempati angka kejadian dan angka kematian tertinggi ke 4 di dunia sedangkan di Indonesia menjadi penyebab kematian di urutan ke 2. Sekitar 80%-90% dari kanker servik adalah jenis Squamous Cell Carcinoma (SCC). Kematian sel (cell death) dapat diakibatkan oleh hipoksia jaringan dan sel-sel limfosit yang akan menyerang tubuh sendiri yang di anggap sebagai antigen.Tujuan Penelitian: Mengetahui biological behavior sel-sel kanker serviks jenis Squamous Cell Carcinoma berkaitan dengan cell death, vaskularisasi, dan reaksi limfositMetode: Desain penelitianini adalah cross sectional . Data penelitian ini adalah data sekunder dari rekam medis dan preparat pulasan Hematoksilin Eosin dari sel endotel kanker serviks yang didapatkan dari laboratorium Patologi Anatomi Asri Medical Center(AMC) dan Cito Yogyakarta periode Januari 2013 – April 2014. Hasil Penelitian: Berdasarkan data yang diambil di AMC dan Lab Cito Yogyakarta periode 2013 – 2014 didapatkan 13 sampel penelitian. Tidak ditemukan korelasi yang bermakna antara cell death dengan vaskularisasi (p= 0.14) sertahubungan cell death danjumlahlimfosit (p= 0.34).Kesimpulan: Tidak terdapat hubungan antara cell death dengan vaskularisasi ataupun hubungan yang signifikan antara cell death dengan reaksi limfosit pada kanker serviks jenis SCC. Background: Cervical cancer is one of health problem that leading cause of the incidence and deathworldwide, while in Indonesia the cause of death in order to 2. An estimated 80% - 90% of cervical cancer is a type of Squamous Cell Carcinoma (SCC). Cell death can be caused by tissue hypoxia and lymphocyte cells that will attack the body itself that is considered as an antigen.Objective: To identify biological behavior of cancer cells Cervical Squamous Cell Carcinoma types associated with cell death, vascularization, and lymphocyte reaction.Methods: A cross sectional survey was performed.Medical record and slide of hematoxylin eosin staining of endothelialc ells were obtained from cervical cancer laboratory Asri Anatomical Pathology Medical Center (AMC) and Cito Yogyakarta period January 2013 - April 2014.Results: Sample collection was 13 samples from AMC and Cito Lab Yogyakarta. There was no significant correlation between cell death with vascularization (p = 0:14) and the relationship of cell death and the number of lymphocytes (p = 0.34). Conclusions: There was no relationship either between cell death with vascularization or a significant relationship between cell death and the reaction of lymphocytes in cervical cancer types SCC. ]]>
<![CDATA[Determinan Biologi Maternal Dan Sosial Ekonomi Apakah Yang Berhubungan Dengan Persalinan Tindakan SC Pada Ibu Bersalin Di RSU Wiradadi Husada ]]>
<![CDATA[Refni Riyanto]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.145-161
<![CDATA[Maternal Biological And Socio-Economic Determinants Are Associated With Delivery of SC Actions in Maternal Maternity at Wiradadi Husada General Hospital Background: Prevalence of maternal mortality in Indonesia on 2010 was 228/100.000 live births. Childbirth complication was a risk factor of prevalence of maternal mortality. Number of childbirth complication was estimated 31%. Theincidence of complications of childbirth labor requires action to improve maternal morbidity . However , delivery to the action has the risk of maternal morbidity and mortality is higher than the persalianan without action or normal delivery . The high number of deliveries through the action section is Cesaria ( SC ) in Wiradadi Husada Hospital due to several factors including maternal factors biological and socio-economic factors that accompany the birth mothers. Objective: The objective of the study to identified determinant of maternal biology ang economic social whether related to childbirth sectio caesarea action on women giving birth in public hospitals Wiradadi Husada Method: The study was an analitic observational study using case control design. The population of the study was 144 subjects, consists of two groups, namely case group and control group, with 1:1 comparison. Sampling method using purposive sampling. Data was a secondrary data and was collected by observation sheet. Data analysis using univariat analysis, bivariat analysis through pearson chi square and multivariat analysis. Result: There are three maternal biological factors related to labor actions in RSU Wiradadi SC Husada ie maternal age (p value 0.002 <0.05) , nutritional status (p value 0.024 < 0.05) , and a history of birth complications (p value 0,000 <0 , 05). There are two socio-economic factors associated with labor action in RSU Wiradadi SC Husada, namely economic status (p value 0.03 <0.05) and geographic groups (p value 0.012 <0.05). Conclussion: Based on the results of the study showed that variables history of birth complications are the most dominant veriabel related to childbirth sectio caesarea action on women giving birth in Public Hospitals Wiradadi Husada. ]]>
<![CDATA[Analisis Kepatuhan Perawat Dalam Melaksanakan Standar Prosedur Operasional Pemasangan Ventilator Di Rumah Sakit PKU Muhammadiyah Yogyakarta ]]>
<![CDATA[Maria Ulfa]]>;
<![CDATA[Fiqih Adhyaksafitri]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.117-126
<![CDATA[Analysis of Nurse Compliance in Implementing Standard Operating Procedures for Installing Ventilators at PKU Muhammadiyah Hospital YogyakartaBackground: The application of standard operating procedures (SOPs) for installing ventilators is one of the efforts to prevent and control infection. Implementation of SOPs depends on nurse compliance which can varybecause it is influenced by internal factors (gender, knowledge, and attitudes) and external factors (group and job characteristics).Objectives: To determine the level of nurse compliance, as well as the relationship and influence of internal and external factors on nurse compliance in implementing SOP for ventilator installation at PKU Muhammadiyah HospitalYogyakarta.Methods: This research is an observational analytic with a cross-sectional approach. The results are presented descriptively followed by bivariate analysis and multivariate analysis. The research subjects were ICU nurses at PKU Muhammadiyah Hospital Yogyakarta. The research instrument is a questionnaire andObservation checklist which was also matched with the interview sheet.Results: Attitudes, knowledge, and external factors contribute to nurse compliance by 34.4% and attitude is a factor that influences nurse compliance.Conclusion: Some nurses still do not fully comply with the SOP, the recommendation that needs to be done is to increase nurse compliance by increasing monitoring, providing training and motivation of nurses in complying with the SOP on ventilator installation.Latar belakang: Penerapan standar prosedur operasional (SPO) pemasangan ventilator adalah salah satu upaya pencegahan dan pengendalian infeksi. Pelaksanaan SPO bergantung pada kepatuhan perawat yang dapat bervariasi karena dipengaruhi oleh seperti faktor internal (jenis kelamin, pengetahuan, dan sikap) serta faktor eksternal (karakteristik kelompok dan pekerjaan). Tujuan Penelitian: Untuk mengetahui tingkat kepatuhan perawat, serta hubungan dan pengaruh faktor internal dan faktor eksternal terhadap kepatuhan perawat dalam melaksanakan SPO pemasangan ventilator di RS PKU Muhammadiyah Yogyakarta.Metode: Penelitian ini adalah analitik observasional dengan pendekatan cross-sectional yang hasilnya disajikan secara deskriptif dilanjutkan analisis bivariat dan analisis multivariat. Subjek penelitian adalah perawat ruang ICU RS PKU Muhammadiyah Yogyakarta. Instrumen penelitian ini adalah kuesioner dan checklist observasi yang juga dicocokkan dengan lembar wawancara.Hasil dan Pembahasan: Sikap, pengetahuan, dan faktor eksternal memberikan kontribusi terhadap kepatuhan perawat sebesar 34,4% dan sikap merupakan faktor yang berpengaruh terhadap kepatuhan perawat.Kesimpulan: Beberapa perawat masih tidak mematuhi SPO sepenuhnya, rekomendasi yang perlu dilakukan adalah meningkatkan kepatuhan perawat dengan cara meningkatkan monitoring, memberikan pelatihan dan motivasi perawat dalam mematuhi SPO pemasangan ventilator.]]>
<![CDATA[Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar) ]]>
<![CDATA[Muhammad Fadhol Romdhoni]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.162-169
<![CDATA[The Effect of Oral Formalin on Gastric Mucosa of Wistar Strain White Rats (Rattus Norvegicus Wistar Strain) Background: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this research is prove the Effect of Formaldehyde peroral subacute on the stomach mucosal of White Rat Strain Wistar (Rattus Norvegicus strain wistar)Method : The design of the study was pure experimental which usingThe Posttest Control Group Design. Sample were white mice which divided into 4 groups. Group I is as a control, without formaldehyde, and another groups were given with formaldehyde doses 20 ppm, 40 ppm, and 80 ppm. Result: The results should that formaldehyde can cause hyperplasia, hypertrophic, atopic, chafe (ANOVA p=0.000). The mechanism of action possibility as DNA cross-linked by protein than gene expression anormal. Conclusions: The study concluded that formaldehyde can cause hyperplasia, hypertrophic, atopic, and chafe on the mucosal stomach of white rat strain wistar and further study was needed to know minimum doses than can change of stomach mucosal and than mecahanism of action about them.]]>
<![CDATA[Efek Ekstrak Kulit Manggis Terhadap Gambaran Histopatologi Hepar Tikus Wistar Yang Diinduksi Formalin ]]>
<![CDATA[Afiana Rohmani]]>;
<![CDATA[Maya Dian Rakhmawatie]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.88-95
<![CDATA[Effects of Mangosteen Peel Extract on Histopathological Appearance of Wistar Rats Induced by FormalinBackground: Formalin chemical idamage can stimulate the formation of reactive oxygen species (ROS) compounds that can cause cellular damage to the body. Mangosteen rind is known as a natural antioxidant due to its xanton content.Objective: To determine the effect of mangosteen peel extract on liver histopathology in Wistar rats induced by formalin solution.Methods: 24 rats were divided into 4 groups. The first group is a negative control group (K-), only given a placebo until the termination period. The second group was a positive control group (K+) which was induced by oral formalin for 21 days, then was given a placebo for 7 days. The third group as Treatment group 1 (P1) were induced by oral formalin for 21 days and then given mangosteen peel extract 200mg/kg BW/day for 7 days. The fourth group as Treatment group 2 (P2) were induced by oral formalin for 21 days and then given mangosteen peel extract 400mg/kg BW/day for 7 days. After that, the rats were terminated and their livers were taken to make histopathological preparations.Results: There was a significant difference (p=0.008) in the histopathological picture of liver tissue in the group of rats given mangosteen peel extract 400mg/kg BW/day (P2) and the positive control group (P2). K+). There was no significant difference (p=0.715) in the histopathological picture of liver tissue in the group of rats given mangosteen peel extract 200mg/kg BW/day (P1) and the positive control group (K+). There was a significant difference (0.00) in the histopathological picture of the liver tissue of the negative control group (K-) with the three groups that were induced by formalin, either given mangosteen peel extract (P1 and P2) or not (K+). Latar Belakang : Jejas kimia formalin dapat memacu terbentuknya senyawa reactive oxygen species (ROS) yang dapat menyebabkan kerusakan seluler jtubuh. Kulit manggis dikenal sebagai antioksidan alamiah dari kandungan xanton di dalamnya. Tujuan: mengetahui efek pemberian ekstrak kulit manggis terhadap gambaran histopatologi hepar pada tikus wistar yang diinduksi larutan formalin. Metode Penelitian: 24 ekor tikus dibagi menjadi 4 kelompok . Kelompok pertama merupakan kelompok kontrol negatif (K-), hanya diberi placebo saja hingga masa terminasi. Kelompok kedua merupakan kelompok kontrol positif (K+) yang diinduksi formalin peroral selama 21 hari, kemudian diberi placebo selama 7 hari. Kelompok ketiga sebagai kelompok Perlakuan 1 (P1) yang diinduksi formalin peroral selama 21 hari kemudian diberi ekstrak kulit manggis 200mg/kg BB/hari selama 7 hari. Kelompok keempat sebagai kelompok Perlakuan 2 (P2) yang diinduksi formalin peroral selama 21 hari kemudian diberi ekstrak kulit manggis 400mg/kg BB/hari selama 7 hari. Setelah itu tikus diterminasi dan diambil organ heparnya untuk dibuat preparat histopatologi. Hasil: Terdapat perbedaan yang signifikan (p=0,008) gambaran histopatologi jaringan hepar pada kelompok tikus yang diberi ekstrak kulit manggis 400mg/kg BB/hari (P2) dengan kelompok kontrol positif (K+). Tidak terdapat perbedaanyang signifikan (p=0,715) gambaran histopatologi jaringan hepar pada kelompok tikus yang diberi ekstrak kulit manggis 200mg/kg BB/hari (P1) dengan kelompok kontrol positif (K+). Terdapat perbedaan yang signifikan (0,00) gambaran histopatologi jaringan hepar kelompok kontrol negatif (K-) dengan ketiga kelompok yang diinduksi formalin, baik diberi ekstrak kulit manggis (P1 dan P2) maupun yang tidak (K+)]]>
<![CDATA[Hubungan Self Assessment Dengan Kompetensi Klinik Mahasiswa Kedokteran ]]>
<![CDATA[Andra Novitasari]]>;
<![CDATA[Djunaidi Djunaidi]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.127-134
<![CDATA[Relationship between Self Assessment and Clinical Competence of Medical StudentsBackground: One area of competence that must be possessed by a doctor is introspection and self-development. Self-assessment is an important component in self-development. Students who have been able to carry out self-assessment on one component of clinical competence well are not necessarily able to carry out self-assessment by integrating all components of clinical competence.Objective: This study aims to analyze the relationship between self-assessment and clinical competence of medical students.Methods: This study is an observational study with a cross sectional design which was analyzed by statistical tests which included univariate analysis and bivariate analysis of the variables between the existence of self-assessment and clinical competence of medical students. The sample in this study was 60 7th semester medical students. Sampling was done by consecutive sampling technique.Results: Bivariate analysis using Chi-Square test showed that there was no significant relationship between self-assessment and clinical competence of medical students (p=0.643).Conclusion: Self-assessment of clinical competence has not been able to provide an overview of the actual clinical competence possessed by students Latar Belakang: Salah satu area kompetensi yang harus dimiliki oleh seorang dokter adalah mawas diri dan pengembangan diri. Self assessment merupakan komponen penting dalam pengembangan diri. Mahasiswa yang sudah mampu melakukan self assessment pada satu komponen kompetensi klinik dengan baik, belum tentu mampu melakukan self assessment dengan mengintegrasikan seluruh komponen kompetensi klinik. Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan antara self assessment dengan kompetensi klinik mahasiswa kedokteran. Metode Penelitian: Penelitian ini merupakan studi observasional dengan desain cross sectional yang dianalisis dengan uji statistik yang meliputi analisis univariat, dan analisis bivariat terhadap variabel antara adanya self assessment dan kompetensi klinik mahasiswa kedokteran. Sampel dalam penelitian ini sebanyak 60 mahasiswa kedokteran semester ke-7. Pengambilan sampel dilakukan dengan teknik consecutive sampling. Hasil Penelitian: Analisis bivariat menggunakan uji Chi-Square menunjukkan bahwa tidak ada hubungan yang signifikan antara self assessmen dan kompetensi klinik mahasiswa kedokteran (p=0.643). Kesimpulan: Self assessment terhadap kompetensi klinik belum dapat memberikan gambaran kompetensi klinik yang sebenarnya dimiliki oleh mahasiswa ]]>
<![CDATA[Strategi Bisnis RSU PKU Muhammadiyah Blora Melalui Pemetaan Faktor Internal dan Eksternal ]]>
<![CDATA[Aisyah Lahdji]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.170-179
<![CDATA[Business Strategy of PKU Muhammadiyah Blora Hospital through Mapping of Internal and External FactorsThe changing business environment demands hospital to adjust. the arrangement of strategic planning is required as of the hospital effort to answer the challenge off change. Therefore, the study highlighted in this research relates to the development of business strategy add the General Hospital of PKU Muhammediyah Blora. This research is an operational research conducted with descriptive approach on the service strategy planning in the public hospital (RSU) PKU Muhammadiyah Blora at the year 2016-2020. The result of this research direct the that RS PKU Muhammediyah Blora neat to develop service strategy planning. The developed service strategy planning refers to the result of focus group discussion (FGD) done in this research which had mapped out the strength and weakness owned by General Hospital of PKU Muhammadiyah Blora. The formulated service strategy planning include improving the quality of human resources through education and training programs, specialist scholarship programs for physicians, increasing partnership with specialist physician partners, adding capacity / number of beds, as well as improving service quality. the implementation of developed services strategy planning requires a commitment from all levels off staff in General Hospital of PKU Muhammadiyah Blora.]]>
<![CDATA[Pengaruh Pemberian Etanol Secara Akut Terhadap Memori Kerja Pada Tikus (Rattus norvegicus) ]]>
<![CDATA[Rochman Basuki]]>;
<![CDATA[Merry Tiyas Anggraini]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.96-101
<![CDATA[Effect of Acute Ethanol Administration on Working Memory in Rats (Rattus norvegicus)Background: Acute administration of ethanol can cause neurological disorders, including the prefrontal cortex (CPF) because ethanol is neurotoxic. One of the disorders is a decrease in memory function.Objectives: This study was to determine the effect of acute ethanol administration on spatial working memory in rats.Methods: This experimental study with a posttest-only-randomized control design involved 20 rats (Rattus norvegicus) which were divided into 4 groups (K, P1, P2 and P3) each of 5 animals. Groups P1, P2 and P3 respectively were given 15% intra-peritoneal ethanol at doses of 1, 2 and 3 g/kg/day for 20 days. Memory performance is measured by 8-arm radial maze with the parameter Number of Error, namely the number of type A errors divided by the number of arms entered.Result : After 20 days of ethanol administration, spatial working memory between groups was tested by Kruskal Wallis. The results showed that there was no significant difference, namely 0.070 (p>0.05).Conclusion: There is no significant relationship between spatial working memory in rats after acute administration of ethanol.Latar belakang: Pemberian etanol secara akut dapat menyebabkan gangguan neurologis, diantaranya cortex prefrontalis (CPF) karena etanol bersifat neurotoksik. Salah satu gangguannya berupa penurunan fungsi memori.Tujuan Penelitian: Penelitian ini untuk mengetahui adanya pengaruh pemberian etanol secara akut terhadap memori kerja spasial pada tikus.Metode Penelitian: Penelitian eksperimen dengan desain posttest-only-randomized control ini melibatkan 20 tikus (Rattus norvegicus) yang dibagi menjadi 4 kelompok (K, P1, P2 dan P3) masing-masing 5 ekor. Kelompok P1, P2 dan P3 secara berurutan diberikan etanol 15% intra peritoneal dengan dosis 1, 2 dan 3 g/kgbb/hr selama 20 hari. Kinerja memori diukur dengan maze radial 8 lengan dengan parameter Number of Error yaitu angka kesalahan tipe A dibagi jumlah lengan yang dimasuki.Hasil Penelitian : Setelah pemberian etanol selama 20 hari, memori kerja spasial antar kelompok diuji dengan Kruskal Wallis. Hasil tidak ada perbedaan yang bermakna, yaitu 0,070 (p>0,05).Kesimpulan: Tidak ada hubungan yang bermakna memori kerja spasial pada tikus setelah pemberian etanol secara akut.]]>
<![CDATA[Analisis Letak Sumber Air Rumah Tangga Di Wilayah Kerja Puskesmas Mijen, Semarang Terhadap Bakteri Escherichia Coli ]]>
<![CDATA[Kanti Ratnaningrum]]>;
<![CDATA[Merry Tiyas Anggraini]]>;
<![CDATA[Pujangga P.Y. Dahlan]]>
<![CDATA[ MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 1, No 2 (2015): February ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Semarang ]]>
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DOI: 10.26714/magnamed.1.2.2015.135-139
<![CDATA[Analysis of the Location of Household Water Sources in the Working Area of Mijen Health Center, Semarang Against Escherichia Coli Bacteria Background: Case detection rate of diarrhea in Puskesmas Mijen, Semarang is still relatively high. One cause of diarrhea disease is a condition of polluted water sources such fouling proximity of water sources with a septic tank. Escherichia coli is a bacteria that may be found in contaminated water sources fouling. Coverage field of environmental health in terms of supervision and control of water quality in Puskesmas Mijen is still far from the achievement of the target, based on these data it is necessary to do research to analysis within a septic tank with a household water source for the presence of the bacterium Escherichia coli. Methods: This study is a cross-sectional study conducted in Puskesmas Mijen. The study methods using systematic random sampling method in 10 villages and the sample number were included with proportion estimate formula. Laboratory tests Escherichia coli bacteria levels in the water conducted in the laboratories of the Faculty of Medicine, Universitas Muhammadiyah Semarang. Data were analyzed using chi square test. Result: From the 36 samples of water, we get the result there is no significant relationship between the distance of a septic tank with a household water source for the presence of the bacterium Escherichia coli (P-value = 0.2). Conclusion: There is no related between the distance of the septic tank with a household water source within the findings of Escherichia coli bacteria in the household water in Puskesmas Mijen. ]]>
