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ISM (Intisari Sains Medis) : Jurnal Kedokteran

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Published by Universitas Udayana

ISSN : 25033638 EISSN : - DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.

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Articles 77 Documents

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Search results for , issue "Vol. 10 No. 2 (2019): (Available online: 1 August 2019)" : 77 Documents clear

Cognitive impairment in cerebral toxoplasmosis with pre-HAART HIV infection: a case report Dico Gunawijaya; Dian Kusumastuti; Widya Putra; Nurlina Ekasari
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Background: Dementia can be caused by infection in the central nervous system, primarily by HIV infection. The majority of the symptoms are short-term memory impairment accompanied by concentration and motoric deceleration. Opportunistic infections of Toxoplasma gondii often accompanies and aggravates the cognitive impairment that occurs.Case: Male, 55-year-old, complained by the family to be forgetful and hard to concentrate since last two weeks and got worse over time. The daily activities of the patient were often disturbed. The awareness, cranial nerve, motor function, sensory, and autonomic were within normal limits. Laboratory tests showed reactive IgG anti-toxoplasma (4520.00 IU / mL) and CD4 128 cells/ÂµL. A non-contrast head CT-Scan showed multiple ill-bordered hypodense lesions with broad peripheral edema in left cerebral hemispheres. Test of cognitive function with MoCA-Ina scored 13 and MMSE scored 19.Discussion: Dementia in HIV manifests as a collection of symptoms of cognitive and motor impairment that interfere with daily activities. The pathogenesis is thought to be caused by interactions with viral proteins and secondary inflammation. Chronic toxoplasmosis is associated with the incidence of dementia in HIV, which usually occurs when CD4 <200 cells/ÂµL. The underlying pathology of inflammation responsible for neurotransmitter modulation and oxidative stress. HAART administration related to a risk reduction of dementia in HIV. High penetrating antiretroviral lowers viral load better, so it can reliably reduce inflammation while slowing the progression of cognitive impairment.Conclusion: HIV infection often leads to dementia, either with or without opportunistic infections. Currently, HAART is the only therapy, accompanied by education and follow-up of the patient's cognitive function.

Deteksi dini skoliosis di tingkat Sekolah Dasar Katolik Santo Yoseph 2 Cok Gde Prema Kurnia Baswara; I Wayan Weta; Luh Seri Ani
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: The number of cases of scoliosis found in the world is high reach 4.5% of the total world general population, while for Indonesia and Bali there has been no incidence rate for the scoliosis. The most common case of scoliosis found is idiopathic as much as 80% of the total cases found so far. Early detection of this scoliosis plays a role to know early on whether there are abnormalities in the spine or not and if there is can to be prevented from getting worse.Method: This study is an observational descriptive study by directly measuring the spine of elementary school students by using a scoliometer.Result: Total of 96 primary school students who met the inclusion and exclusion criteria, the most sexes were women with 51 students (53.1%), who were suspected of having scoliosis were 62 (64.4%), on adolecent suspected of scoliosis with 39 students (81,3%) and scoliosis criteria was mostly found in intermediate criteria of 55 students (88,7%)Conclusion: The prevalence of scoliosis in primary school students is 88%, most scoliosis criteria are found at the intermediate level, and female sex is more likely to have scoliosis than men

Usia dan obesitas berhubungan terhadap penyakit batu saluran kemih di RSUP Sanglah Denpasar periode Januari 2014 sampai Desember 2014 Nurfitriani Nurfitriani; Anak Agung Gde Oka
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: Urinary Stone Disease is the process of forming stones caused by the deposition of a substance with excess amounts of urinary or due to other factors that affect the solvency of substance. Urinary Stone Disease is frequently Â Â found on adults between 15-59 years old. Total patient who diagnosed by Urinary Stone Disease in Indonesia is too high. Many things associated against the onset of this disease, such as age and obesity. Therefore the research to examine which factors cause the occurrence of Urinary Stone Disease is necessary in order to raise the early prevention.Method: Research design is descriptive analytic. Using consecutive sampling method. Data will be analyzed in univariate and bivariate using statistical test of chi-square with a level of significance of Î± < 0.05. Place of research in Sanglah Denpasar Bali Subject of research are men and women above 15 years old, diagnosed with Urinary Stone Disease. Subject research are urology unit visiting patient also patient being hospitalized at Sanglah General Hospital.Result: The research results showed that the age has become risk factors which closely related with Urinary Stone Disease, value of p = 0.002. Obesity does not have significant relations against the occurrence of Urinary Stone Disease with value of p = 0,564.Concluison: Age has close relation with the occurrence of Urinary Stone Disease, while obesity has no relation towards the occurrence of Urinary Stone Disease diseases.

Hasil tajam pengelihatan pasca operasi katarak senilis di RSUP Sanglah Denpasar periode Oktober 2016 - Juni 2017 Anak Agung Gde Arisena Asmara; Putu Budhiastra; Ni Ketut Niti Susila
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: Cataract is a type of eye disease that occurs in the lens of the eye. Cataract occurs not only due to the age factor, but also can occur in children born with these conditions or congenital factors. This study aimed to find out visual acuity outcome after senile cataract surgery at RSUP Sanglah Denpasar on October 2016 - June 2017 period.Method: The type of this research was descriptive cross-sectional conducted at RSUP of Sanglah Denpasar using the medical records of the period of October 2016 - June 2017. The sampling technique used the total sampling, with the number of samples of 32 subjects. The result of this research was processed by using a computer software.Result: The postoperative patients with poor outcome tended to be experienced by the senile cataract of mature group compared to the immature that was around 9.1%, borderline outcome tended to be experienced by group with immature senile cataract of 23.8% while the dominant senile cataract outcome was 81.8%. Patients undergoing SICS procedures tended to have a poor outcome compared to those undergoing a phacoemulsification procedure of 16.7%. Borderline outcome tended to the group undergoing phacoemulsification procedures, and 83.3% of the good outcome tended to be experienced by the group undergoing SICS procedures.Conclusion: This research concludes that good outcome come from cataract senile mature group (81.8%) and the group that doing SICS procedure (83.3%)

Hubungan insomnia dengan depresi pada lanjut usia di Sesetan Kecamatan Denpasar Selatan Tahun 2017 Luh Putu Mettary Yasoda Gera; Anak Ayu Sri Wahyuni; IGA Indah Ardani
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: Insomnia is difficulty falling or maintaining sleep that often experienced by general population. Insomnia mostly experienced by elderly woman, people with low education and low economy and in people Â who Â have Â chronic Â disease. Â Insomnia Â isÂ risk Â factor Â from Â psychiatric Â disorder Â especially depression. Insomnia increase the risk in depression development. Depression is disorder on personal, interpersonalÂ and social that affecting general population. The purpose of this study is to know the relationship between insomnia and depression in elderly.Method: The type of this study is analytical observational (Cross-sectional)Â study with amount of sample 32 respondents that conducted in Banjar Gaduh and Banjar Tengah in Sesetan, South Denpasar District in elderly in 2017. This study is using the primary data obtained through questionnaire and interview (GDS and ISI) and analyzed through SPSS 21.0.Result: This study found that from 32 respondents experienced insomnia (50%), not experienced InsomniaÂ Â (50%), Â experiencedÂ Â depressionÂ Â (28.1%) Â and Â no Â experienceÂ Â depressionÂ Â (71.9%) Â and relationship insomnia with depression on eldery obtained value p < 0.05 . The R-square value indicates value of 0.673 which means that role variable independent in explain variable dependent only of 67.3%, could be concluded that still there are 24.6% other variables outside the research variables that affect insomnia.Conclusion: There were a significant relationships between depression and insomnia.

Uji efektivitas ekstrak etanol air kelopak bunga Hibiscus sabdariffa linn terhadap profil lipid tikus hiperlipidemia Ode Mahesa Putra; I Made Jawi; Bagus Komang Satriyasa
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: Cardiovascular disease is still the biggest cause of death in the world. Many factors that play a role in the development of this disease, one of them is Hiperlipidemia. The situation can be handled using conventional medicines, but there are concerns about the side effects of conventional medicines. Hibiscus Sabdariffa L. (roselle) is rich in polyphenols, anthocyanins, flavonoids which can be used as drugs for the prevention of cardiovascular diseases that have biological activities such as antihypertensive, antimutagenic, chemopreventive, antioxidant, anticonvulsant, anxiogenic, CNS-depressant, serotoninergic activity, reducing damage from oxidative liver, anti-inflammatory and hypoglycemic activity. This study aims to evaluate the effects of roselle ethanol extract as a hypolipidemic agent.Method: This study used an experimental design, using wistar mouse divided into five groups: C1 received aquadest intervention, C2 (simvastatin 0.2g / kg / day), I1 (100mg / kg / day roselle extract), I2 (200 mg / kg / day roselle extract), and I3 (300 mg / kg / day roselle extract) mice was given hypercholesterol oil feed for two weeks preceeding drugs intervention, then intervention was given for eight weeks and analyzed on mouse lipid profile component.Result: There were significant differences in total cholesterol, triglyceride, LDL, and HDL values among the intervention groups (p = 0.000). The lowest total cholesterol belonging to the C2 group (117.83 Â± 6.36) was followed by I3 (143.66 Â± 11.75), the lowest triglyceride belonging to the C2 group (284.83 Â± 7.46) was followed by I3 (306.84 Â± 8.61), the lowest LDL was owned by the group C2 (104.50 Â± 4.37), followed by I3 (120.50 Â± 2.42), the highest HDL belonging to the C2 group (44.80 Â± 3.16 followed by I3 group (38.02 Â± 3.40).Conclusion: The ethanol extract at 300mg / kg / day gave better improvement of lipid profile rather than roselle ethanol extract 100mg / kg / day, 200 mg / kg / day, and aquadest control, but still not able to provide better improvement than simvastatin.

Hubungan lingkar perut dengan kadar gula darah puasa pada mahasiswa Fakultas Kedokteran Universitas Udayana angkatan 2014 Alvin Wijaya; Nyoman Wande; Ida Ayu Putri Wirawati
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: Diabetes Mellitus is a metabolic disease characterized by elevated blood sugar levels, either caused by a disturbance of insulin secretion, insulin resistance or both. Obesity is one of the risk factors of diabetes mellitus. The incidence of diabetes mellitus increases from year to year, but the data that discusses the association of risk factors with diabetes mellitus itself, especially obesity is minimum. The purpose of this study is to determine the association of abdominal circumference with fasting blood sugar levels at students of Udayana University Faculty of Medicine class of 2014.Method: This research is an analytical research conducted at Udayana University Faculty of Medicine Campus, Denpasar. Data obtained in the form of primary data in the form of abdominal circumference to see the status of obesity and fasting blood sugar to see the status of diabetes mellitus. Data were analyzed using SPSS program.Result: The results showed that there was not significant negative association between abdominal circumference with fasting blood sugar levels at Udayana University, Faculty of Medicine students class of 2014. However, this association is not statistically significant because diabetes mellitus influenced by many factors other than obesity. In addition, it can be seen that the characteristics of the population did not describe the population of diabetes mellitus or obesity, thus affecting associations that have been described in some literature and the concept of author thinking. But indeed the association of anthropometric risk factors (abdominal circumference) has a greater value than other risk factors.Conclusion: There was a negative correlation between abdominal circumference and fasting blood sugar but not significant statistically

Karakteristik diare pada anak di RSUP Sanglah Denpasar tahun 2017 I Dewa Made Satrianjaya; Ni Nyoman Metriani Nesa; Dewi Sutriani Mahalini
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Background: Diarrhea is one of the most common diseases affecting children around the world. In Indonesia, the national rate of diarrhea prevalence is 9% where 16.7% of cases occur at 1-4 years old and 16.5% of cases at under one year old. In addition, dehydration causes most mortalities. Aim: This study aims to determine the characteristics of diarrhea in children in Sanglah General Hospital, Denpasar. Method: Thisstudyis a cross-sectional study design using secondary data from the register data in the Pediatric Division of Sanglah General Hospital Denpasar from January to November 2017. Of the 170 data, there were 165 survival samples. Characteristics of diarrhea in children are described using tables, pie charts, and graphs.Result: Most of the sample were males (56.5%), infants (40%), patients from Denpasar (55.3%) and those with good nutritional status (60%). The mean age of the patient was 26.6 months, the mean body weight was 10.6 kg, and the mean height was 79.8 cm. Most of them were diagnosed with acute diarrhea (98%), where the most common cause is a viral infection (75%). The most common comorbid diseases are congenital heart disease and neurological disease (10.6%). Most patients have only mild dehydration (57%). Long term treatment of diarrhea patient in child wards mostly for 2-3 days.Conclusion: Diarrheain children in Sanglah Denpasar Hospital period January-November 2017 most suffered by men and babies, mostly from Denpasar. Most of them have acute diarrhea that is mainly caused by a viral infection.

The correlation between demography and clinical status based on WHO staging in MSM HIV patients at Bali Medical Centre Dhanesh Sukumar Nair; I Nyoman Sutarsa; A A Sagung Sawitri; Komang Ayu Kartika Sari
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Background: HIV stands for human immunodeficiency virus which is in the category of lentivirus (a subgroup of retrovirus) that causes HIV infection and can lead to acquired immunodeficiency syndrome (AIDS).Â HIV affects specific cells of the immune system, called CD4 cells, or T cells. Over time, if left untreated, HIV can destroy so many of these cells that the body would not be able to fight off infections and disease. However, with proper medical care, HIV can be controlled. Treatment for HIV is called antiretroviral therapy (ART). It involves taking a combination of HIV medicines (called an HIV regimen) every day. Today, a person who diagnosed with HIV before the disease is far advanced and who gets and stays on ART can live a nearly normal lifespan.Aim: This study aims to investigate and analyze the predictors that influence WHO staging of homosexual MSM HIV patients treated at the BMC hospital in Bali. Indonesia, and to determine the factors that lead to differences in the WHO staging in MSM patients with HIV.Method: This study used a retrospective cohort method using secondary data from BMC Hospital. The sample population for this research is MSM HIV patients treated at the BMC hospital in Bali. Using the total sampling method yielded 271 samples.Result and Conclusion: the HIV incidence is a serious matter in Indonesia. One of the underlying factors for the delayed diagnosis of HIV is the lack of knowledge about the improved prognosis of early ARV treatment and a fear of being stigmatized by the community. Increased availability of HIV testing at hospitals, combined with enhanced knowledge of the prognosis of HIV treatment among crucial affected population, and the community at large and may improve earlier testing.

Pola Kuman dan Uji Kepekaan Antibiotik Pada Pasien Unit Luka Bakar RSUP Sanglah Periode 1 Januari 2016 - 1 Januari 2017 I Wayan Jorden Junior; I Made Suka Adnyana; I Wayan Subawa; Vivi Paula Putri
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Background: Burns are a skin injury or injury caused by thermal that causes morbidity or mortality in patients, due to either heat or radiation, electrical and chemical reactions. In burns can occur bacterial growth that will cause an infection, both gram-positive bacteria and gram-negative bacteria. Necessary antibiotics in the treatment of infection by bacteria on burns. The incidence of burns is increasing from year to year, but data in Indonesia that discuss about the number of infections in burns and the use of antibiotics is still small.Aim: The study aims to determine the pattern of germs and antibiotic sensitivity test in patient burn unit at Sanglah Denpasar Hospital period January 2016 - January 2017.Method: This research is a descriptive descriptive cross sectional study conducted at Sanglah Denpasar General Hospital (RSUP). Data obtained in the form of secondary data of medical record of patient period January 2016 - January 2017. Data were analyzed by using SPSS program.Result: The results showed that from 63 patients, found 51.0% gram positive and 49.0% gram negative. In the positive gram found 8 species of bacteria with the most bacteria that is Staphylococcus aureus 15.87% and Strep Î² Haemolyticus 15.87% and gram negative found 3 types of bacteria with the highest number Pseudomonas aeruginosa 30.16%.Conclusion: Antibiotics with the highest resistance were found Amoxicillin 85.7%, Amoxicillin / Sulbactam 81.2% and Ampicillin 87.5% while the highest sensitivity antibotics were Amikacin 82.3%, Meropenem 75.0% and Linezolid 85.7% both on gram negative and gram positive.

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