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Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 12 Documents
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Search results for , issue "Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi" : 12 Documents clear
STUDI FITOKIMIA DAN FARMAKOLOGI BAWANG DAYAK (Eleutherine palmifolia (L.) Merr) Resha Rosalia; Devia Setyaningsih; Aghnia Ahda; Salma Aziz; Siti Lulu Luthfiah; Vera Dwi Apriani; Sri Tantia Dinita; Yuliani Dewi; Mira Oktaviani Malik
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.381

Abstract

At present, the existence of herbal medicines has succeeded in attracting global attention and many countries in the world are participating in conducting research on these herbal medicines. There are many diseases that can be looked for alternatives with compounds found in plants, including one of the Dayak Onion species (Eleutherine palmifolia (L.) Merr) which can be used as microbial agents, anti-inflammatory, antihypertensive, antidiabetic, antidermatophyte, anti-melanogenic and has anti-inflammatory activity. cytotoxic because of the content of flavonoids, alkaloids, saponins, tannins, steroids or triterpenoids, phenols, and quinones and their derivatives. There are many other uses of Onion Dayak which are only based on empirical experience. Therefore, further development in pharmacological research on Dayak Onions is needed to fulfill the medical interests of the general public.
STUDI FITOKIMIA DAN AKTIVITAS FARMAKOLOGI DARI KULIT BATANG MESOYI (Massoia aromatica Becc.) Resha Rosalia; Devia Setyaningsih; Aghnia Ahda; Salma Aziz; Siti Lulu Luthfiah; Vera Dwi Apriani; Sri Tantia Dinita; Yuliani Dewi; Mira Oktaviani Malik
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.382

Abstract

For a long time, nature with all its wealth has been used by humans as a necessity of life including medicine. Today, traditional medicine with the use of plants is much in demand by people all over the world. One of the benefits-rich plants commonly used is the skin of the mesoyi stem (Messoia aromatica Becc.) which phytochemically contains flavonoid compounds, phenolics, alkaloids, steroids, triterpenoids, saponins, tannins, calcons, and coumarins. Based on pharmacological studies this plant can act as antimicrobial, phagocytic, cytotoxic, anti-inflammatory, immunomodulatory, antioxidant, analgetic, as well as other effects by inhalation. However, if further research is done, there may be more pharmacological activity resulting from this plant. Therefore, research on this plant still needs to be developed so that it can be used as a reference for traditional medicine.
PENGOBATAN PENYAKIT KOLESTROL DENGAN MENGGUNAKAN EKSTRAK HERBAL DI INDONESIA - A REVIEW Maharni Apriana; Rifqi Maulana Toni; Muhammad Choerul Huda; Zulva Mustofa Kamal; Rita Khoerunnisa; Allahuddin Allahuddin; Retna Ayu Septiani; Sayyid Rafli Ash-Shidiqi; Fera Anggraeni
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.383

Abstract

Health problems are one of the most complex problems, the sanitation process in improving health with various uses of plants in Indonesia. A country that will be rich in natural resources such as some herbal plant extracts. As a form of serious treatment to improve the health of cholesterol disease in Indonesia, namely herbal plant extracts by utilizing the active substances contained in these plants in the form of flavonoids, saponins, HMG Co-A reductase, phenolics, hypocholesterolemic curcumin, and Beta Sitosterol through both in vitro and in vivo tests, which have important properties in the cholesterol treatment process, such as improving public health in Indonesia.
STUDI FITOKIMIA DAN FARMAKOLOGI DAUN MANGKOKAN (Nothopanax scutellarium) Adinda Putri Sabrina; Evi Tania; Nurhalifah Nurhalifah; Robby Alvian; Santika Citra Veronita; Shella Imka Puji; Siti Nuryamah
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.384

Abstract

Nothopanax Scutellarium (Araliaceae family), commonly known as the leaves of the bowl, is a medicinal plant that has many pharmacological properties. The leaves of this plant have various uses in traditional medicine for a number of diseases. There are so many substances contained in this plant such as flavonoids, saponins, tannins, phenolics, alkaloids, steroids and so on. Several studies have demonstrated the pharmacological exploration of Nothopanax Scutellarium as a Culex sp mosquito larvicide, diuretic, anti-kidney stone solubility, anti-aging, burn healer, anti-oxidant and anti-bacterial which were carried out experimentally both in vivo and in vitro.
AKTIVITAS IMUNODULATOR DARI JAWER KOTOK (Coleus scutellariodes (L) Benth) Adinda Putri Sabrina; Evi Tania; Nurhalifah Nurhalifah; Santika Citra Veronita; Shella Imka Puji; Siti Nuryamah
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.385

Abstract

Coleus scutellariodes (L), commonly known as Jawer kotok plant, is a medicinal plant that has many properties, one of which is as an immunodulator and some of its pharmacological activities. The leaves of this plant have various uses in traditional medicine for a number of diseases. Lots of substances contained in this plant such as flavonoids, saponins, tannins, alkaloids, steroids. One of the substances contained in jawer kotok leaves has efficacy as an immunodulator, namely flavonoids. Several studies have demonstrated the pharmacological exploration of Coleus scutellariodes (L) as an infectious disease (Tuberculosis), Anti-Inflammatory (vulvovaginal candidiasis), Antipyretic, Antioxidant-Active, Anti-diabetic, Anti-histamine, Anti-anthelmic. In this journal review, a comprehensive study focused on knowledge of plant functions as immunodulators, pharmacological activities and phytochemical studies of the jawer kotok plant Coleus scutellariodes (L).Keywords: Guides, instructions, author’s kit, conference publications.
SKRINING FITOKIMIA DAN UJI ANTIOKSIDAN TERHADAP EKSTRAK BUNGA Limnocharis flava L DENGAN METODE DPPH Ermi Abriyani; Lia Fikayuniar; Mia Anisa Silvi; Arie Wichandar
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.392

Abstract

Genjer (Limnocharis flava L.) is of plants that bloom throughout the year. The part that can be used of Limnocharis flava L. is leaves, but more people used stems and flowers of Limnocharis flava L. for consumption. The present study has aim to determine the phytochemical screening and antioxidants activity assay of Limnocharis flava L. bloom extracts. Method of the research are extraction by maceration, screening phytochemical, DPPH method which is by measuring the capture of synthetic radicals in polar organic solvents at room temperature. The results of phytochemical screening of Limnocharis flava L. bloom are flavonoid, saponin, tannin, polyphenols, quinone. Antioxidant activity assay of Limnocharis flava L. bloom from three extracts have resulted IC50 value from methanol extract 61.4224 ppm, ethyl acetate extract 160.4368 ppm and n-hexane 433,2932 ppm. Methanol extract has a stronger antioxidant compared to ethyl acetate and n-hexane extracts by DPPH method.
UJI AKTIVITAS ANTIJAMUR EKSTRAK DAUN (Ipomoea carnea Jacq) TERHADAP Candida albicans Lia Fikayuniar; Ermi Abriyani; Rizmayanti Intan Ferdiansah; Sumiyati Sumiyati; Santa Regina Sianipar; Selvia Aziza
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.393

Abstract

Infectious diseases can be transmitted from one person to another or from animals to humans of the causes of infection diseases is fungi. Fungi are microorganisms in the form of cells or branched threads. These microorganisms have a rigid cell wall and composed of polysaccharides or chitin, have nuclei and spores, are not chlorophyllous and do not multiply sexually and asexually. Based on this, research was carried using of the welling method on antifungal bioactivity as well as a thin layer chromatography test of spotting to determine the content of secondary metabolites contained in the leaves of kale fence. This study aims to determine the bioactivity of secondary metabolites in n-hexane extract, ethyl acetate, and methanol of kangkong pagar leaves (Ipomoea carnea Jacq) against Candida albicans fungi. This study made four different concentrations namely 60%, 80%, 100%, 120%, for positive control using ketoconazole and negative control using CMC 1%. Data analysis is using the One Way ANOVA test. From this study, the results were that kale fence leaf extract contains secondary metabolites, namely flavonoids, tannins, steroids. Then the results of the antifungal activity test of fencing kale leaves have activities that can inhibit fungi at a concentration of 120% with an inhibitory zone diameter of 11,254 mm so that they can be classified as strong antifungal bioactivity, in the results of the One Way ANOVA analysis of the three samples (N Hexana, Methanol and ethyl Acetate), it is known that the Sig value is 0.000 < 0.05 so it can be said that the rata_rata is "Significantly Different".
UJI TOKSISITAS MENGGUNAKAN METODE BSLT DAN SKRINING FITOKIMIA EKSTRAK (Melastoma malabathricum L.) Lia Fikayuniar; Ermi Abriyani; Fioren Irwandira; Sinta Bela; Sartika Dewi
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.394

Abstract

Melastoma malabathricum L. plant or commonly known as senduduk is often used as a source of food and medicine. The stem of senduduk is one part of the senduduk plant that has not been widely utilized in existence compared to its flowers, fruits and leaves. Senduduk plant has activity as antidiarrhea, fractures, digestive tract disorders, melancholy, seizures, epilepsy, abdominal pain, thrush, anti-inflammatory, antipyretic, wound, and antioxidant, in addition to the myriad benefits of M. malabathricum L. also contains toxic compounds. Therefore, this study aims to determine the toxic activity of n-hexane extract, ethyl acetate, senduduk stem methanol (M. malabathricum L.) against A. salina L. shrimp larvae to avoid toxic risks in humans. The method used in the study was the Brine Shrimp Lethality Test (BSLT) using 10 shrimp larvae A. salina L. in each replication carried out three times afterwards followed by probit analysis to see the percentage of shrimp larva death. The study also found results that n-Hexane extract contains flavonoids, quinones and saponins, while ethyl acetate and methanol extracts contain only flavonoids and quinone. Senduduk stem extract (M. malabathricum L.) has a toxic effect with a value of LC50 < 1000 ppm or in the n-Hexane extract of 1.66 ppm, while in ethyl acetate extract of 56.23 ppm and methanol extract of 128.82 ppm.
UJI KUALITAS KITOSAN DARI LIMBAH TULANG SOTONG DENGAN VARIASI SUHU DEASETILASI Iin Lidia Putama Mursal; Farhamzah Farhamzah; Ajeng Selistiawati; Dewi Sheyka Meli; Nanda Chaerani; Naufal Muyasyar; Tita Latipah; Vivi Vidia
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.395

Abstract

Research has been carried out on testing the quality of characteristics chitosan from cuttlefish bone waste with variations in deacetylation temperature. The purpose of this study is to identify the potential of cuttlefish bone as a raw material for producing chitosan and the effect of variations in deacetylation temperature on the quality of the chitosan. The tests of water content, ash content and chitosan solubility values. Solubility test showed that the three samples were soluble in 2% acetic acid. The results of the water content test with variations in deacetylation temperatures of 110 0C, 120 0C, 130 0C were 0.3467%, 0.1063% and 0.0135%, respectively. The ash content of chitosan is 0.2627%, 0.0125% and 0.0060%. The results of testing water and ash content showed a decrease in the value linear within increasing temperature.
REVIEW ARTICLE : AROMATERAPI SEBAGAI TERAPI STRES DAN GANGGUAN KECEMASAN Adinda Khansa Sundara; Bintang Larasati; Dewi Sheyka Meli; Dheandra Mariska Wibowo; Fitri Nurulliza Utami; Silky Maulina; Yuliana Latifah; Neni Sri Gunarti
Jurnal Buana Farma Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v2i2.396

Abstract

Stress and anxiety are one of the mental disorders that are still a problem in Indonesia. Stress and anxiety can be experienced by anyone that can be caused by certain conditions. Aromatherapy treatment is an alternative to reduce stress and anxiety levels. Aromatherapy is a therapy that uses essential oils as the main agent. The purpose of this study was to determine which essential oils can reduce stress and anxiety levels in various patient conditions. The method used in this research was a literature review study consist of 16 article from online search site . The results of the study showed that essential oils from lavender (Lavandula angustifolia), bergamot orange (Citrus bergamia Risso et Poiteau), lemon (Citrus limon (L.) Burm. F), peppermint (Mentha piperita L.), chamomile (Matricaria Chamomilla L), ylang flower (Cananga Odorata (ylang-ylang)), lemongrass (Cymbopogon ciratus (DC.), bitter orange (Citrus aurantium (L.), and rosemary (Rosemarinus officinalis L.) can be used to reduce stress and anxiety levels caused by certain conditions.

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