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Krisni Subandyah
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Departemen Ilmu Kesehatan Anak FKUB (Department of Pediatrics, Faculty of Medicine, Universitas Brawijaya). Jl. Jaksa Agung Suprapto No. 2 Malang, Provinsi Jawa Timur, Indonesia
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INDONESIA
Pediatric Sciences Journal
Published by Universitas Brawijaya
ISSN : 27220427     EISSN : 27221474     DOI : https://doi.org/10.51559/pedscij
Core Subject : Health,
Health Professions Public Health
Pediatric Sciences Journal (PedSciJ) is published by the Medical Faculty of Brawijaya University, Indonesia, as an Open Access & Peer Reviewed Multidisciplinary Journal. The aims and scope of the Journal include pediatric, neonatal healthcare, and perinatology/ The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship and to encourage a vigorous dialogue between medical scholars and practitioners. The Journal welcomes contributions that promote the exchange of ideas and rational discourse between practicing educators and medical researchers worldwide. Pediatric Sciences Journal (PedSciJ) publishes peer-reviewed clinical research articles, case reports, serial case reports, systematic reviews, meta-analyses, and letters to the editor twice a year in June and December. Articles published in the Pediatric Sciences Journal (PedSciJ) embrace the full scope of the manuscript related to the health and diseases of infancy, neonates, children, adolescents, and those related to pediatric topics. The Journal also explores legal and ethical issues, neonatal technology, and product development based on COPE. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians, pediatric subspecialists, obstetrics, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists
Arjuna Subject : Kedokteran - Pediatrics, Perinatology, and Child Health
Articles 5 Documents
 1 
Search results for , issue "Vol. 3 No. 2 (2022): Available online : 1 December 2022" : 5 Documents clear
Pericardial effusion in status epilepticus and global developmental delay one-year-old patient with co-exist of atrial septal defect: a case report Pradhika Perdana Sakti; Ariani
Pediatric Sciences Journal Vol. 3 No. 2 (2022): Available online : 1 December 2022
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v3i2.33

Abstract

Introduction: Atrial septal defect (ASD) is one of the most common types of congenital heart disease (CHD) and occurs due to spectrum closure failure during the intrauterine period. ASD is generally asymptomatic, but it can affect patients from various aspects. Case presentation: A 1-year-old 4-month-old girl was referred with a major complaint of shortness of breath as early as 6 days before hospital admission. The dullness accompanied by a fever disappears, as convulsions, pallor and vomiting. On physical examination, a positive result in pathological reflex was found in a decrease in consciousness, epicantal fold, conjunctiva and pale skin, and edema of the left limb. The patient was examined for echocardiography and found the presence of moderate primum ASD with a left to the right pyre, mild tricuspid regurgitation with the possibility of pulmonary hypertension, and effusion pericardium with the collapse of the right atrium. In the laboratory results show the presence of normochromic normocytic anemia, leukocytosis, mild hyponatremia, hypokalemia, hypocalcemia, hypophosphatemia, increased PCT, increased SGOT / SGPT, PT elongation, a decreased of free T4 and increase in TSH, IgG CMV (+), IgG toxoplasma (+), IgG HSV-1 (+), IgG HSV-2 (+), and IgG Rubella (+). The patient is given treated at the PICU and provided with the help of ventilation, antibiotics, antipyretics, anticonvulsants, inotropic, and sympathomimetic agents. On the ninth day of care, the patient experienced cardiac arrest. RJP was performed, but the patient did not have ROSC and was pronounced dead. Conclusion: ASD affects the patient's condition as well as the patient's survival both directly and indirectly. There is a link between ASD and developmental disorders, pericardial effusion and patient mortality. It is necessary to conduct a comprehensive evaluation and management of patients with ASD.
Quality of life in children with chronic disease in Malang city assessed using pediatric quality of life inventoryTM Yaalmolly Vinothini Ravindran; Irfan Agus Salim; Haryudi Aji Cahyono
Pediatric Sciences Journal Vol. 3 No. 2 (2022): Available online : 1 December 2022
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v3i2.36

Abstract

Introduction: A chronic disease is known to be a condition that affects daily function and daily activity which tends to cause someone to be hospitalized. A chronic disease in children triggers several changes in physical, social, emotional, and educational aspects and it can affect the quality of life and development of the child. The purpose of this study is to determine the quality of life of children with chronic disease in Malang city using PedsQLTM. Method: This study is an analytic observational study using a cross-sectional design. Data collection was using purposive (non-probability) sampling with a total sample of 82 respondents. Data collection was carried out using a generic PedsQLTM questionnaire version 4.0 with a google form. Data analysis was performed using Univariate analysis (Descriptive Respondents) and bivariate analysis (Correlation Analysis using Chi-Square). Results: The results showed that the factors that are significantly associated with the quality of life of children are the type of disease and the child's nutritional status (p-value= 0.005; 0.009< Level of Significance = 0.05) while other factors such as age, gender, parents' knowledge, and education background, duration of disease, parents' social and economic condition and several children are not significantly associated with the quality of life. Conclusion: The factors that are significantly associated with the quality of life of children were the type of disease and nutritional status.
Intravenous aminophylline treatment for severe asthma exacerbation in a toddler: an evidence-based case report Merrynta Rahmania; Ery Olivianto
Pediatric Sciences Journal Vol. 3 No. 2 (2022): Available online : 1 December 2022
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v3i2.39

Abstract

Introduction: Asthma is the most prevalent chronic condition in childhood causing enormous morbidity and mortality worldwide. Acute severe exacerbations are potentially life-threatening and often need hospitalization. Incomplete or poor response to initial treatment requires additional interventions that commonly are intravenous second-line drugs, of which Aminophylline is one of them. Although Aminophylline is costly and effective, views are polarising that its use is unsafe. Herein we report a case of intravenous aminophylline use in severe asthma exacerbation in a toddler. Case description: A 3-year-old boy previously diagnosed with asthma came to the emergency room due to severe shortness of breath. He had breathlessness which was more pronounced when he was lying down. He looked restless and irritable. Bilateral wheezing, tachypnea, tachycardia and chest withdrawal were noted. Because of poor response to standard initial treatment, intravenous Aminophylline was given and showed complete relief without the occurrence of the anticipated serious adverse event. Conclusion: When first-line inhaled/nebulized medication fails to control a child's asthma exacerbation, Aminophylline may be utilized. It must be considered a cost-effective treatment for acute asthma exacerbations, especially for developing countries with limited health budgets, even though it is thought to have a narrow therapeutic range and a large inter-individual variance in clearance.
The importance of correct management in a 15-year-old boy with severe pulmonary arterial hypertension associated with patent ductus arteriosus Dyahris Koentartiwi; Devi Albaiti Jannati; Ardhanis Ramadhanti; Heny Martini
Pediatric Sciences Journal Vol. 3 No. 2 (2022): Available online : 1 December 2022
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v3i2.44

Abstract

Background: Pulmonary arterial hypertension (PAH) is a condition in which pulmonary vascular pressure increases and is associated with diverse diseases or aetiologies. In children, 50% of PAH cases are caused by congenital heart disease (CHD), especially due to large left-to-right shunts. Large systemic to pulmonary shunts may develop in PAH if left untreated or repaired late. PAH, when present, markedly increases morbidity and mortality in patients with CHD. Case presentation: We present a 15-year-old boy with a large patent ductus arteriosus (PDA) and severe pulmonary arterial hypertension. Catheterization under general anaesthesia was performed at the age of 16 years. We performed an acute vasoreactivity test (AVT), with the AVT result showing pulmonary arterial hypertension with high flow and low resistance. Transcatheter closure (TCC) of PDA was performed, resulting in no residual PDA. Meanwhile, the echocardiographic finding showed that there was still class II pulmonary arterial hypertension. We then gave heart failure medication and selective pulmonary vasodilator for 6 months. Post-treatment, pulmonary artery systolic pressure was significantly lower (TR Vmax 2.31 m/s, TR Max PG 21 mmHg, estimated PAP 24 mmHg). In this case, clinical evaluation, CXR, ECG, echocardiography, and cardiac catheterization data were presented with a review of the current guidelines regarding the management of paediatric patients with PAH associated with PDA. Summary: TCC of PDA is an option to treat pulmonary hypertension in PDA patients. Combined use of drugs and TCC PDA proves beneficially synergistic effect with better outcomes and may reduce mortality.
Comorbidities as risk factors for clinical outcomes in pediatric patients with COVID-19: a comprehensive literature review Saptadi Yuliarto; Kurniawan Taufiq Kadafi; Rakhman Tyas Perdana; Takhta Khalasha
Pediatric Sciences Journal Vol. 3 No. 2 (2022): Available online : 1 December 2022
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v3i2.40

Abstract

Background: The population that in a high risk to have a svere COVID-19 infection is children. The difficulties can influence the risk of controlling their hygiene and be worsened by the immaturity immune system, especially in children with comorbidities. Moreover, this problem needs to be prioritized in children. Despite in worldwide spread of severe COVID-19 infection, there are limited data regarding severe COVID-19 disease in children. Thus, we investigated the effects of comorbidities as risk factors for clinical outcomes in paediatric patients with COVID-19. Methods: This comprehensive literature review was from the PubMed, Google Scholar, and Science Direct databases through January 2021. The keywords used to obtain the literature include “COVID-19”, “coronavirus”, ” pediatric”, ”children”, ”severity”, ”comorbidity”, ”mortality”, ”death,” and “intensive”. The article with the inclusion criteria was involved. The information about the COVID-19 severity and underlying comorbidities in children were the main criteria that were enrolled. Results: The severe clinical risk factors in paediatric patients with COVID-19 that are reported most often are chronic lung disease (including asthma) (4312 critical patients), obesity (1007 critical patients), diabetes mellitus (815 patients), cardiovascular disorders (677 patients) and neurological disorders (542), prematurity (183 patients) and immunosuppression conditions including malignancy (143 patients). Other conditions in the form of hematological disorders, airway abnormalities, malnutrition and gastrointestinal disorders can also contribute to the clinical severity of paediatric COVID-19 patients. Conclusion: Children with underlying diseases such as obesity, chronic lung disease, cardiovascular disease, and neurologic disease had a higher risk of severe COVID-19 than children without comorbidities.

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