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Hadi Barru Hakam Fajar Siddiq
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jifakfar@gmail.com
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Lembaga Penelitian dan Pengabdian Masyarakat Akademi Farmasi Jember. Jl. Pangandaran No. 42 Antirogo, Jember
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Jurnal Ilmiah Farmasi Akademi Farmasi Jember
Published by Akademi Farmasi Jember
ISSN : 25034707     EISSN : 2615756X     DOI : https://doi.org/10.53864/jifakfar
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Farmasi Akademi Farmasi Jember merupakan Jurnal yang menampung artikel ilmiah hasil penelitian di seluruh bidang Farmasi, seperti Farmasi Bahan Alam, Kimia Farmasi, Farmasetika, Farmasi Klinis, Farmasi Komunitas, dan bidang farmasi lainnya.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "2019: Desember - Vol.3 No.2" : 5 Documents clear
SINTESIS DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA TURUNAN AMOKSISILIN TERHADAP Escherichia coli Hadi Barru Hakam Fajar Siddiq, Siti Nur Azizah, Amaliyah Nurul Hidayah, Dewi Riskha Nurmalasari, Mau
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.552 KB) | DOI: 10.53864/jifakfar.v3i2.33

Abstract

Amoxicillin derivate compounds from the reaction of amoxicillin with p-aminophenol are synthesized compounds by reacting amoxicillin and p-aminophenol. . Escherichia coli is a flora normal bacteria that can causing infectious diseases. This research aimed to determine the antibiotic activity of amoxicillin derivat compound (amoxicillin with p-aminophenol) on the growth of E. coli. This research was conducted using the disc diffusion method. amoxicillin derivat compound (amoxicillin with p-aminophenol) were characterized by organoleptic test, melting point determination, pH test determination, Rf value, and maximum wavelength. The results of the organoleptic test showed that amoxicillin derivates from amoxicillin and p-aminophenol reaction is crystal powder, dark brown and bit bitter. Melting point of amoxicillin derivates from amoxicillin and p-aminophenol reaction was 160ºC. pH test of amoxicillin derivates from amoxicillin and p-aminophenol reaction was 6,5. Rf value of amoxicillin derivates from amoxicillin and p-aminophenol reaction was 0,79. The results of UV wavelength scanning showed that amoxicillin derivates from amoxicillin and p-aminophenol reaction at 295 nm. Antibiotic activity showed by the clear zone form around the paper disk. The results showed that E. coli was resistant to pure amoxicillin. Amoxicillin derivat compound (amoxicillin with p-aminophenol) with concentrations of 100% and 12,5% have the largest inhibitory zones (6,33 mm) compared with concentrations of 50% and 25%, 5,33 and 6,00 mm respectively. Based on these results it can be concluded that derivat compound of amoxicillin (amoxicillin with p-aminophenol) has antibiotic activity against the growth of E. coli that has been resistant to pure amoxicillin.Keywords: Derivate compound of amoxicillin, Escherichia coli, antibiotic activity
AKTIVITAS ANTITUBERKULOSIS EKSTRAK KULTUR CAIR Streptomyces ENDOFIT RIMPANG Kaempferia galanga TERHADAP Mycobacterium tuberculosis RESISTEN Siti Nur Azizah, Mikhania Cristiningtyas Eryani
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.566 KB) | DOI: 10.53864/jifakfar.v3i2.34

Abstract

The objective of this research was to examine the antituberculosis activity of drug resistant stains using liquid culture extracts Streptomyces Kaempferia galanga rhizomes. The endophytes Streptomyces, there were KJ.3A, KJ3B, KJ.4, and KJ.11. Two resistant strain of Mycocacterium tuberculosis were used, there were HE strain which resistant to isoniazid dan etambutol and SR stainswhich resistant to streptomisin and rifampisin. The liquid culture extracts of Streptomyces endophytes was obtained from centrifugation method by growing Streptomyces colony into YMB media Antituberculosis activity was using Lowen-stein Jensen (LJ) methode after incubation for 8 weeks. The result showed that the four liquid culture extracts Streptomyces endophytes have not been able to inhibit the growth of Mycobacterium tuberculosis in both HE and SR strainsKeywods: Antituberculosis, endofit Streptomyces, resistant M. tuberculosis
EVALUASI PENGELOLAAN OBAT PADA EMERGENCY KIT DI RUANGAN RAWAT INAP PADA RUMAH SAKIT BINA SEHAT JEMBER Kukuh Judy Handojo, Vieca Fauziah , Dewi Rashati
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (471.928 KB) | DOI: 10.53864/jifakfar.v3i2.35

Abstract

Emergency kit management is an important thing to get pay attention because it might be prompt the sentinel event and undesirable effect. Emergency preparations are the medicines that categorized as life saving or life threatening medicines including the medical devices that support emergency condition. The purpose of this study was to determine the percentage of medicine management of emergency kit. The type of research used is descriptive qualitative research and cross sectional (point time approach). The research was conducted in June 2018 at Bina Sehat Hospital Jember. Population and sample in this research is all the medicine management of emergency kit which exist in inpatient room of Bina Sehat Hospital Jember. The sampling technique used is total sampling technique, where all the population used as sample. Research tool of data collection used in this research is using check list. The result of medicine management of emergency kit percentage in inpatient room of Bina Sehat Hospitel Jember regarding the storage management of medicines in emergency kit as much as 59% according to SOP. Distribution of medicines in emergency kit as much as 86,7% according to service guidelines. Replacement medicines that has been used as much as 83% according to SOP. Replacement medicines that damaged or expired as much as 66,6% according to SOP. Monitoring of medicines in emergency kit as much as 84% according to SOP.Keywords : Evaluation, Management, Emergency kit, Pharmacy Installation, Emergency medicine
PENGARUH VARIASI KONSENTRASI HPMC SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK GEL ANTINYAMUK DAUN KENIKIR (Tagetes erecta L.) Mikhania C.E., Asa Falahi, Dewi Ratna Sari
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.641 KB) | DOI: 10.53864/jifakfar.v3i2.31

Abstract

The aim of this research was to understand the influence of HPMC variation concentration to the physical characteristic anti mosquito gel of extract kenikir leaves (Tagetes erecta L.). Pre-experiment the one shot case study was used as the research design. The variation of HPMC concentration were 2%; 2,5% and 3%. The materials used in this research were kenikir leaves extract, propylenglycol, methyl paraben, jasmine oil and aquadest. The result show that the variation concentration of HPMC give influence to physical properties of organoleptic gel (form, colour), pH and viscosity. The variation concentration of HPMC did not influence homogeneity, spreadibility and smell of the gel.Keywords : Kenikir leaves, HPMC, Anti Mosquito Gel.
PENGARUH VARIASI KONSENTRASI GELLING AGENT HPMC (Hidroxypropyl methylcellulose) TERHADAP SIFAT FISIK GEL EKSTRAK ETANOL BIJI EDAMAME (Glycine max) Dewi Rashati, Icha Ayuning Suprayitno
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (158.753 KB) | DOI: 10.53864/jifakfar.v3i2.32

Abstract

Edamame seeds (glycine max (L) merr) is a soybean variety that is harvested while still young. Isoflavones present in soybeans such as deidzein, glycitein, and genistein have activity in inhibiting the tyrosinase enzyme to achieve skin lightening effects for skin whitening cosmetics. In this study the gel was formulated with HPMC (Hydroxypropyl methylcellulose) 2%, 3%, 5% as a gel forming agent. Evaluation includes organoleptic, homogeneity, pH, viscosity, and spreadability. The results of organoleptic evaluation of gel form in formula 1 fulfill the requirements, in formula 2 and 3 do not meet the requirements. The physical properties of the odor and color organoleptic formulas 1, 2, and 3 are eligible. in the homogeneity test of formulas 1, 2, and 3 are homogen. In the pH test formula 1,2,3 fulfills skin pH susceptibility pH 6. In the viscosity test of formula 1 250 dPa.S, Formula 2 500 dPa.S and formula 3 800 dPa.S.in the spread test of formula 1 it is 4.4cm, formula 2 is 3.8cm, and formula 3 is 3.7cm. From the results test of the Formula 1 (2% HPMC) meets all physical requirements of the gels.Keywords :Gel, HPMC, Sifat Fisik Edamame

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