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INDONESIA
Indonesian Journal of Cancer
Published by National Cancer Center-Dharmais Cancer Hospital
ISSN : 19783744     EISSN : 23556811     DOI : https://www.doi.org/ 10.33371
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
Indonesian Journal of Cancer is a peer-reviewed and open-access journal. This journal is published quarterly (in March, June, September, and December) by Dharmais Cancer Hospital - National Cancer Center. Submissions are reviewed under a broad scope of topics relevant to experimental and clinical cancer research. Articles are original research that needs to be disseminated and written in English. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted acceptance for publication. The journal publishes original research articles, case reports, and review articles under the following categories: cancer management, cancer prevention, cancer etiology, epidemiology, molecular oncology, cancer diagnosis and therapy, tumor pathology, surgical oncology, medical oncology, radiation oncology, interventional radiology, as well as early detection.
Arjuna Subject : Kedokteran - Onkologi
Articles 6 Documents
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Search results for , issue "Vol 11, No 1 (2017): Jan-Mar" : 6 Documents clear
Uncommon Glomus Tumor at The Volar Area of Distal Phalang: a Case Report WAHYU WIDODO; ARYO NUGROHO TRIYUDANTO
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (460.598 KB) | DOI: 10.33371/ijoc.v11i1.498

Abstract

ABSTRACTIntroduction: Glomus tumor, a benign rare neoplasmic perivascular lesion arising from glomus neuromial-arterial tissue. Glomus cells, which are found in the dermis throughout the body, are responsible for thermoregulation. In this tumor, its cells proliferate and surround the vascular canals, producing a classic clinical sign such as spontaneous pain, pain on light touching, and temperature hyperesthesia. Despite its rare occurrence, it is necessary to know how recognize and treat this variant of perionychium tumor. Case Illustration: A forty-seven-year old woman came with pain on the tip of her ring finger since 3 years before admission. Over time, the tingling sensation worsened and eventually pain emerged. The appearance of her ring finger and nail were normal. However, the patient felt pain after a light touch and paresthesia especially at the volar side of her ring finger. Having normal radiograph appearance, excisional biopsy was then performed. Histologic examination showed a well-defined lesion encapsulated by a fibrous capsule. The lesion consisted of several thin-walled flared vascular containments with layers of glomus cells around it, which is in accordance with characteristic of benign glomus tumor.At the latest follow up, there were no complication or recurrence found. The pain and paresthesia around the ring finger were also diminished. Conclusion: Despite its rare occurrence, the diagnosis of Glomus Tumor can be performed clinically. Excisional biopsy is the definitive treatment and specific diagnostic modality for Glomus Tumor.ABSTRAKGlomus tumor adalah tumor jaringan lunak yang cukup jarang ditemui dan merupakan lesi perivaskular yang muncul dari arteri glomus neuromial. Sel glomus berproliferasi dan mengelilingi kanal vaskular. Tumor ini sering ditemukan pada area subungual. Tanda khasnya adalah nyeri spontan, nyeri pada sentuhan ringan, dan sensitivitas terhadap suhu. Kemampuan mengenali dan mengobati tumor perionychium ini penting. Wanita usia 47 tahun datang dengan keluhan utama nyeri pada jari manis sejak 3 tahun lalu. Seiring waktu, sensasi kesemutan dan nyeri memburuk. Pada pemeriksaan fisik di regio distal phalang tidak ditemukan bengkak dan kemerahan, deformitas, atau massa. Kulit intak tanpa perubahan warna dengan sekitar. Kuku tampak normal. Pada palpasi didapatkan nyeri pada sentuhan ringan di area volar dengan VAS 4-5 dan paresthesia pada sisi volar. Pemeriksaan x-ray menunjukkan hasil normal. Pada pemeriksaan biopsi eksisional dan pemeriksaan histopatologi ditemukan lesi berbatas tegas yang terdiri atas kapsula fibrosa dengan beberapa lapis dinding dan vaskular serta sel glomus yang menutupinya. Tiga bulan pasca-operasi tidak ditemukan nyeri dan paresthesia pada lokasi tumor. Tumor glomus adalah tumor yang jarang dan dapat didiagnosis melalui tampilan klinis. Biopsi eksisional merupakan pengobatan definit, sekaligus modalitas diagnostik spesifik.
Sebaran Kanker di Indonesia, Riset Kesehatan Dasar 2007 MAKASSARI DEWI
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (493.456 KB) | DOI: 10.33371/ijoc.v11i1.494

Abstract

ABSTRACTCancer is one of the leading causes of death in the world. It takes an evidence-based strategy to address the increasing incidence of cancer in the world. To control the increase of cancer in Indonesia required control strategies of the key riskfactors associated with the incidence of cancer. Currently the data on the distribution of cancer in Indonesia is still limited. Key risk factors for cancer can be known from the existing types of cancer. By knowing the distribution of cancerthat is expected to become a factor in the prevention of cancer in Indonesia. The purpose of this paper is to describe the distribution of cancer in Indonesia by the community in 2007. The data used is data survey of basic health research(Riskesdas) 2007. Design this study was a descriptive cross-sectional. The analysis showed that from 768 635 respondents there were 4647 (0.6%) respondents who had cancer. Central Java province was the province with the highest number of cancer patients (23.6%). Cervical and ovarian cancer as well as breast cancer were the most commonly found as many as 927 (20%) of respondents to cervical and ovarian cancer, and as many as 746 (16%) of respondents had breast cancer. Cervical and ovarian cancer were most commonly found in adults, with the status ofmarried, live in urban areas and have low education status. Breast cancer was most common in women aged adult, married status, living in urban, low educational status and low economic status.ABSTRAKKanker merupakan salah satu penyebab kematian utama di dunia. Dibutuhkan strategi berbasis bukti untuk mengatasi meningkatnya kejadian kanker di dunia. Untuk mengontrol peningkatan kanker di Indonesia diperlukan strategipengendalian faktor risiko kunci yang berhubungan dengan kejadian kanker. Saat ini, data tentang sebaran kanker di Indonesia masih terbatas. Faktor risiko kunci kanker dapat diketahui dari jenis kanker yang ada. Dengan mengetahuisebaran kanker yang ada diharapkan dapat menjadi salah satu acuan dalam penanggulangan kanker di Indonesia. Tujuan dari tulisan ini adalah untuk menggambarkan sebaran kanker di Indonesia berdasarkan komunitas pada tahun2007. Data yang digunakan adalah data surveI Riset Kesehatan Dasar (Riskesdas) 2007. Desain studi ini adalah deskriptif cross-sectional. Hasil analisis menunjukkan bahwa dari 768.635 responden, 4.647 (0,6%) responden di antaranya menderita kanker. Jawa Tengah merupakan provinsi dengan jumlah penderita kanker tertinggi (23,6%). Kanker serviks uteri dan ovarium serta kanker payudara merupakan jenis kanker yang paling banyak ditemukan, yaitu 927 (20%) responden untuk kanker serviks uteri dan ovarium serta 746 (16%) responden kanker payudara. Kanker serviks uteri dan ovarium paling banyak ditemukan pada usia dewasa, dengan status menikah, hidup di perkotaan, dan memiliki status pendidikan rendah. Kanker payudara paling banyak ditemukan pada wanita usia dewasa, status menikah, tinggal di perkotaan, status pendidikan rendah, dan status ekonomi rendah.
Systemic Management of Relapse Wilms Tumor After Radical Nephrectomy in An Adult Female, A Case Report IDA BAGUS OKA WIDYA PUTRA; EDWARD USFIE HARAHAP; RACHMAT BUDI SANTOSO
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.181 KB) | DOI: 10.33371/ijoc.v11i1.499

Abstract

ABSTRACTWilms tumor (nephroblastoma) is rare in adults. We present a case of 28-year old female with Wilms tumor diagnosed with pre-operative abdominal magnetic resonance imaging, histopathological analysis and immunohistochemistry. She had relapse tumor two years after primary open radical nephrectomy. She was managed with chemotherapy with the ICE regimen (ifosfamide, carboplatin, and etoposide) for six cycles with partial response and excellent functional status. Keywords: ABSTRAKTumor Wilms (nefroblastoma) adalah kasus yang jarang ditemukan pada orang dewasa. Kami melaporkan satu kasus, pasien perempuan, 28 tahun dengan tumor Wilms yang didiagnosis dengan pemeriksaan magnetic resonance imaging pre-operasi, histopatologi, dan imunohistokimia. Pasien tersebut mengalami relaps dua tahun pasca-radikal nefrektomi. Pasien kemudian menjalani kemoterapi dengan regimen ICE (ifosfamid, karboplatin, dan etoposid) selama enam siklus dengan repons parsial dan status fungsional baik.
Hubungan antara Tingkat Gejala Depresi dengan Stadium Kanker Payudara di Poli Onkologi Satu Atap (POSA) RSUD Dr. Soetomo, Surabaya NISA’AFIDATUN HARIROH; KHAIRINA KHAIRINA; HANTORO ISHARDYANTO
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (457.609 KB) | DOI: 10.33371/ijoc.v11i1.495

Abstract

ABSTRACTA diagnosis of breast cancer raises a meaningful stress and can get depressed. By knowing the emotional state of breast cancer patients who experience symptoms of depression after being diagnosed, treatment can be done in a comprehensive manner with the hope of treatment can be wor optimally. The purpose of this research is to know the relationship of depression symptoms with breast cancer stage in POSA RSDS. Type of research is observational analytic on breast cancer patients first visit POSA RSDS June-July 2016. This research use questionnaire BDI-II to measure the subject's sympto ms of depression. Analytical test used is the Spearman Correlation. Results, obtained 43 subjects entirely women with most age range 45-59 years (60.5%), educational history most high school(41.9%), and most work as housewives (74.4%). 46.5% dominated by stage III, and 62.8% BDI-II results with no symptoms of depression. Analytical test indicates a weak relationship (Sig. 0.009 < 0.396, rs = 0.05). A weak relationship between variables because distribution of uneven stage; the majority of the BDI-II showed no symptoms of depression, acceptance phasebetween subjects against the conditions of his illness, researchers estimate the condition of the spirituality subject is good and can affect the subject's emotional condition conducive for researchers. Spirituality subject of research is good to make the subject of the research arose from slump, and the subject of more religious, positive support from family, positive support from fellow cancer survivors who have been healed. Conclusion, there is a relationship between depression symptoms with the staging of breast cancer. ABSTRAKDiagnosis kanker payudara menimbulkan stres yang bermakna dan dapat mengalami depresi. Dengan mengetahui keadaan emosional pasien kanker payudara yang mengalami gejala depresi setelah didiagnosis, dapat dilakukanpengobatan secara komprehensif dengan harapan pengobatan dapat berjalan secara optimal. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat gejala depresi dengan stadium kanker payudara di Poli Onkologi Satu Atap RSUD Dr. Soetomo, Surabaya (POSA RSDS). Jenis penelitian adalah analitik observasional pada pasien kanker payudara kunjungan pertama POSA RSDS bulan Juni – Juli 2016. Penelitian ini menggunakan kuesioner BDI-II untuk mengukur gejala depresi subjek. Uji analitik yang digunakan adalah Spearman Correlation. Hasil penelitian mendapatkan 43 subjek, seluruhnya wanita dengan rentang usia terbanyak 45 – 59 tahun (60,5%), riwayat pendidikan terakhir terbanyak SMA (41,9%), dan pekerjaan terbanyak sebagai ibu rumah tangga (74,4%). Sebanyak 46,5% didominasi stadium III dan 62,8% dengan hasil BDI-II tidak ada gejala depresi. Uji analitik menunjukkan hubungan yang lemah (Sig.0,009 < 0,396, rs = 0,05). Hubungan yang lemah antara variabel dikarenakan distribusi stadium tidak merata, mayoritas hasil BDI-II menunjukkan tidak ada gejala depresi, dalam fase acceptance (menerima) antara subjek terhadap kondisi sakitnya. Peneliti memperkirakan kondisi spiritualitas subjek cukup baik sehingga dapat memengaruhi kondisi emosional subjek peneliti untuk kondusif. Kondisi spiritualitas subjek penelitian yang cukup baik membuat subjekpenelitian bangkit dari keterpurukan dan subjek lebih religius. Dukungan positif diperoleh dari keluarga dan sesama penderita kanker yang telah sembuh. Kesimpulannya, terdapat hubungan antara tingkat gejala depresi dengan stadium kanker payudara.
Profil Jantung Pasien Akut Limfoblastik Leukemia Anak yang Mendapatkan Terapi Anthracycline DAVID VICTORY WA’U; SRI MULATSIH; INDAH KARTIKA MURNI
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.452 KB) | DOI: 10.33371/ijoc.v11i1.496

Abstract

ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common malignancy in children under fifteen years of age. Advanced cancer therapy with anthracycline has increased survival rate but also chronic health problem and the most iscardiovascular. This study aims to describe cardiac events of ALL patients who received anthracyline during chemotherapy. We conducted a cross sectional study of childhood ALL who were hospitalized at DR Sardjito hospital between April and June 2016. Electrocardiography (ECG) and echocardiography were performed. Results of this study shows childhood ALL who received anthracycline may suffer from cardiotoxicity. Cardiac events can be found in all stage of chemotherapy.ABSTRAKLeukemia limfoblastik akut (LLA) adalah keganasan yang paling banyak dialami anak di bawah usia 15 tahun. Kemajuan pengobatan kanker dengan anthracycline telah meningkatkan angka kesintasan penderita LLA dan masalah kesehatan kronik, terutama penyakit kardiovaskuler. Penelitian ini bertujuan untuk mengetahui kelainan jantung pada pasien LLA yang mendapatkan kemoterapi anthracyline. Penelitian dilakukan secara potong lintang dengan subjek anak penderita LLA yang dirawat di rumah sakit Dr. Sardjito antara April–Juni 2016. Pasien menjalani pemeriksaan elektrokardiografi (EKG) dan echocardiography. Penelitian ini menyimpulkan bahwa anak penderita ALL yang mendapatkan anthracycline dapat mengalami kardiotoksisitas. Kelainan jantung dapat ditemukan pada semua tahap kemoterapi.
Stereotactic Ablative Body Radiotherapy (SABR) in The Management Spinal Metastases: A Brief Overview* HENRY KODRAT; SOEHARTATI GONDHOWIARDJO
Indonesian Journal of Cancer Vol 11, No 1 (2017): Jan-Mar
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (660.549 KB) | DOI: 10.33371/ijoc.v11i1.509

Abstract

It is well known that radiotherapy provides successful pain relief in bone metastases. Advancements in imaging and radiotherapy delivery technology have enabled safe delivery of higher dose radiotherapy, which will produce more durable tumor control. Over the last decades stereotactic radiosurgery (SRS), which delivers high dose radiation, has been successfully used for the treatment of intracranial lesions. The good results obtained in SRS have led to development of extra cranial stereotactic radiosurgery known as stereotactic ablative body radiotherapy (SABR). This review paper enlightens indication, target definition, efficacy and toxicity in spinal SABR.ABSTRAK Radioterapi telah terbukti sebagai modalitas yang dapat menghilangkan nyeri pada metastases tulang. Kemajuan dalam teknologi pencitraan dan pemberian radioterapi telah memungkinkan pemberian radioterapi dosis tinggi dengan aman, di mana hal ini dapat meningkatkan kontrol lokal. Selama dekade terakhir ini, stereotactic radiosurgery (SRS) yang memberikan radiasi dosis tinggi dinyatakan bermanfaat untuk tatalaksana berbagai kelainan intrakranial. Hasil cukup memuaskan yang diperoleh SRS mendorong untuk dikembangkan stereotactic radiosurgery ekstrakranial yang kemudian dikenal sebagai stereotactic ablative body radiotherapy (SABR). Tinjauan pustaka ini menjelaskan indikasi, target radiasi, efektivitas, dan efek samping pada prosedur SABR spinal.

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