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INDONESIA
Indonesian Journal of Pharmaceutical Research
Published by Universitas Muhammadiyah Sumatera Barat
ISSN : -     EISSN : 27765075     DOI : -
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology Public Health
Indonesian Journal of Pharmaceutical Research (IJPR) is a peer-reviewed open-access journal related to the pharmaceutical sciences and related disciplines, as well as pharmaceutical practice. It is the journal of the Department of Pharmacy, Faculty of Pharmacy, Muhammadiyah University of Sumatera Barat, published semi-annually online and in print by the UMSB Press. IJPR publishes reviews, opinion articles, research papers, and communications including: Pharmacognosy and Pharmaceutical Biology Medicinal and Pharmaceutical Chemistry Pharmacology Pharmacokinetics and Pharmacodynamics Pharmaceutical Technology Pharmaeconomy Community Pharmacy Practice Pharmaceutical Care and Clinical Pharmacy Social Pharmacy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 24 Documents
 1   2   3 
Anti-Inflammatory Activity Test of Ethanol Extract of Ambarella Fruit Leaves (Spondias dulcis Frost) Against Male Rats Induced Carrageenan Ahmad Syukur Hasibuan
Indonesian Journal of Pharmaceutical Research Vol 1, No 2 (2021): Indo J Pharm Res 2021 1(2)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v1i2.2830

Abstract

In the treatment of inflammation, there are several chemical drugs, namely steroidal and non-steroidal anti-inflammatory drugs, but because they have many side effects, anti-inflammatory drugs are developed from natural ingredients, especially plants. Plants are scientifically proven to have anti-inflammatory properties, one of which is ambarella fruit leaves because it leaves contain flavonoid secondary metabolites as anti-inflammatory compounds. The objective of this study to determine the effect of giving ambarella fruit leaves on anti-inflammatory activity in male rats induced by carrageenan. The method used in this study was paw edema, namely by induction of carrageenan 0.1 ml as an irritant on the soles of the rat's feet for 360 minutes with the parameter observed was the inhibition of edema in the feet of rats using a plethysmometer. This study was an experimental study that was divided into 5 groups, namely the control group positive (diclofenac sodium 9 mg/kgBW), negative control (Na-Cmc 0.55), and three doses tested, namely 100 mg/kgBW, 300 mg/kgBW and 500 mg/kgBW. The results of this study showed a significant difference (p<0.05) where flavonoid compounds from ambarella fruit leaves affect anti-inflammatory activity. The conclusion that the three doses is tested, namely 100 mg/kgBW, 300 mg/kgBW and 500 mg/kgBW has an anti-inflammatory effect where the more effective dose was 300 mg/kg kgBW.
Determination of Total Phenolic Compounds and SPF ( Sun Protection Factor)Value of Methanol Extract & Fraction Brotowali Leaves ( Tinospora crispa L.) Zuraida Sagala; Riong Seulina Panjaitan
Indonesian Journal of Pharmaceutical Research Vol 3, No 1 (2023): Indo J Pharm Res 2023 3(1)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v3i1.4589

Abstract

Flavonoid is one of the compounds that are important for the body because it has a function as an antidote to free radicals by overcoming and preventing the occurrence of oxidative stress conditions are antioxidants. Phenolic compounds are known to have antioxidant activity due to the substitution of hydroxy groups at the ortho and para positions to the – OH and –OR groups. Phenolic compounds are known to have various pharmacological activities, one of that is photoprotective which useful for protecting the skin from the dangers of UV exposure. Brotowali contains secondary metabolites such as alkaloids, phenolics, steroids, and tannins. The presence of these compounds indicates that brotowali has the ability to inhibit free radical compounds. This study aims to determine the total phenolic levels and SPF (Sun Protection Factor) in methanol extract and leaf fraction of brotowali (Tinospora crispa L.). The research methods include maceration, fractionation, phytochemical screening test, specific and non-specific parameter testing, assay by Folin-Ciocalteau method using gallic acid as a standard, and SPF (Sun Protection Factor) value. Based on the research results obtained, the ethyl acetate fraction of brotowali leaves contains phenolic compounds of 675.6522 mg GAE/gram sample with the highest SPF value at a concentration of 1000ppm of 48.79.
Description of Drug Storage in Melawai Kemang Pharmacy in 2018 Nurwulan Adi Ismaya; Nining Prihatin; Okpri Melia; Nur Hasanah
Indonesian Journal of Pharmaceutical Research Vol 1, No 1 (2021): Indo J Pharm Res 2021 1(1)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v1i1.2436

Abstract

Drug management is the most important management in pharmaceutical services at the pharmacy. Drug storage is an inseparable part of all pharmaceutical activities. Pharmacies including pharmacy service facilities, therefore they must be responsible for drug inventory, maintaining drug supplies to avoid damage and maintaining drug quality. Medicines distributed at pharmacies are the same as drugs distributed in hospitals, therefore a good drug storage system at the pharmacy is the same as storing good medicine in hospitals. This type of research is descriptive research with the main purpose of making an objective picture. Data collection is retrospective by observing and reviewing documents following the drug storage indicators by Pudjaningsih. The population of the study were all medicines. Samples were taken based on the total sampling technique. The research instrument is a stock card and the document resulting from stock opname. The conclusion of this research is an overview of drug storage at Melawai Kemang Pharmacy with indicators suitability of stock card is 97,16 %, percentage of drugs expired and or damaged.
Carbohydrate Content in Packaged Chicken Nuggets: Qualitative And Quantitative Analysis Syifa Alifia Indriani; Nurul Asfia; Agnes Manongga; Riong Seulina Panjaitan
Indonesian Journal of Pharmaceutical Research Vol 2, No 2 (2022): Indo J Pharm Res 2022 2(2)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v2i2.4174

Abstract

Nugget products can be made from beef, chicken, fish, and other ingredients, but chicken nuggets are the most popular in the community. Chicken nuggets are products produced from the marinated, ground, minced, and cooked parts of chicken breast meat with breadcrumbs. Qualitative and quantitative tests of carbohydrates are carried out to determine the presence of carbohydrates present in nuggets. Qualitative tests are based on changes in color or deposits formed, while quantitative tests to determine the carbohydrate levels contained in each test material with DNS method. The results showed qualitative analysis of molisch test carbohydrates on samples of chicken meat nuggets brand "B," which positively contained carbohydrates (glucose), while samples of chicken meat nuggets brands "A" and "C" showed negative results. In the Iodin test, all three nugget samples showed positive results for glycogen. The Benedict test yielded negative results for all three nugget samples, indicating that none of them contained sucrose. The three nugget samples all failed the Barfoed test, indicating that they are all members of the disaccharide group. The Seliwanoff test yielded negative results for all three nugget samples, all of which contained glucose, mannose, or galactose. The Osazon test yielded negative results for all three nugget samples. Carbohydrate quantitative test obtained sample concentration on sample nugget of chicken meat brand "A" 0.49 mg/mL, sample of chicken meat nugget brand "B" 0.48 mg/mL and sample nugget of chicken meat brand "C" 0.56 mg/mL. Carbohydrate qualitative analysis on samples of chicken meat nuggets from brand "B" reveals that they positively contain carbohydrates as well as fructose and glycogen. The "C" brand chicken meat nugget sample has a high concentration for quantitative analysis of carbohydrates, indicating that the sample contains more carbohydrates.
Determination of % Caffeine Levels in Packed Black Haidar Dwi Putranto; Riong Seulina Panjaitan; Violetta Djohansah; Liany Carolina Rambulika; Marisa Tamara Sari
Indonesian Journal of Pharmaceutical Research Vol 2, No 1 (2022): Indo J Pharm Res 2022 2(1)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v2i1.3479

Abstract

Kafein diketahui memiliki efek farmakologi yaitu sebagai stimulan sistem saraf pusat dan metabolisme selain itu dapat digunakan untuk pengobatan dalam mengurangi kelelahan fisik dan juga dapat meningkatkan tingkat kewaspadaan. Penelitian ini bertujuan untuk mengetahui kadar kafein dalam 25 gram (10 kantong teh celup) dari 3 kemasan yang berbeda. Teh hitam di ekstraksi dengan metode maserasi menggunakan pelarut air. Di gunakan 3 merek teh hitam celup antara lain Teh Hitam Merek A memiliki massa kafein 24 mg dengan % kadar kafein adalah 0,096%, Teh Hitam Merek B memiliki massa kafein 22,5 mg dengan % kadar kafein adalah 0,09% dan Teh Hitam Merek C memiliki massa kafein 24,6 mg dengan % kadar kafein adalah 0,0984%. Menurut SNI 01-7152-2006 batas maksimum mengkonsumsi kafein baik secara langsung maupun tercampur di dalam makanan atau minuman adalah 150 mg/hari atau 50 mg/sajian.
The Identification of Mercury in The Urine of Night Cream Users in Midwifery Program Abdurrab University Harni Sepriyani; Wahyu Margi Sidoretno; Mega Elfia
Indonesian Journal of Pharmaceutical Research Vol 1, No 2 (2021): Indo J Pharm Res 2021 1(2)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v1i2.2831

Abstract

White and bright skin is everyone's dream. Many women who do facial skin care in order to obtain healthy facial skin and attractive appearance. Facial skin care that is mostly done is the use of facial whitening creams. Face whitening cream is believed to be able to remove or lighten black spots on facial skin. Whitening cream that is often used is a night cream. Some of the night creams sold have not received permission from National Agency of Drug and Food Control of Indonesia. Usually these creams contain heavy metals, such as mercury. Mercury is toxic which when exposed and absorbed by the body can cause loss of enzyme ability in the body to cancer. The purpose of this study was to determine the presence or absence of mercury in the night cream and urine of night cream users at Abdurrab University Midwifery Study Program students. The method of this research is a qualitative examination on samples of night cream and urine used KI reagent. The results showed that the night cream sampled gave a positive test result and the urine of night cream users gave a negative test result. The conclusion of this study is that the night cream sampled contained mercury and the urine of night cream users did not contain mercury.
Test Carbohydrate and Protein Content in Commercial Condensed Milk (SKM) Qualitative and Quantitative Riong Seulina Panjaitan; Yulius Evan Christian; Bagas Eva Wijaya; Rahmat Andrian
Indonesian Journal of Pharmaceutical Research Vol 3, No 1 (2023): Indo J Pharm Res 2023 3(1)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v3i1.4606

Abstract

Sweetened condensed milk (SKM) is a milk product obtained by evaporating some of the water from pure milk with the addition of sugar. SKM is not a sterile product, but its preservation depends on the sugar content; (1) Background: Qualitative and quantitative tests of carbohydrates and proteins were carried out to determine the presence of carbohydrates and proteins in SKM. The qualitative test is based on a change in color or precipitate formed, while the quantitative test is to determine carbohydrate and protein levels; (2) Method: Qualitative and quantitative test of carbohydrates with the DNS method. Qualitative and quantitative test of protein with the Lowry method; (3) Results: Qualitative analysis of carbohydrates Molisch test on SKM "A", "B", "C", "D", "F" is positive, while SKM "E" is negative. The Osazon test on SKM "A", "B", "C", "D", "F" is positive and SKM "E" is negative. Iodine test, Benedict's test, Barfoed's test, Seliwanoff's test showed positive. Quantitative test for carbohydrates, sample concentration SKM "A" 0.228mg/mL the lowest value and SKM "F" 1.544mg/mL the highest value. Biuret test protein qualitative analysis on SKM "A", "B", "C" is positive while SKM "D", "E", "F" is negative. The Ninhydrin test on SKM "D", "F" is positive while SKM "A", "B", "C", "E" is negative. Sulfur test on SKM "A", "B" is positive while SKM "C", "D", "E", "F" is negative. Xantoprotein test on SKM "A", "C", "D", "E", "F" was positive while SKM "B" was negative. The Neuman test on SKM "D", "E", "F" is positive while SKM "A", "B", "C" is negative. Quantitative protein test for SKM“B” concentration was 10.77mg/mL, the lowest value, and the SKM “D” sample was 90.11mg/mL, the highest value; and (4) Conclusion: The qualitative analysis of carbohydrates SKM "A", "B", "C", "D", "F" showed positive and the quantitative test of SKM "F" contained high carbohydrates. Whereas SKM "A", "D", "F" showed positive protein and the SKM "D" quantitative test contained high protein.
The Effect of Drying Method on The Antioxidant Activity of The Flesh of Nutmeg Fita Selonni
Indonesian Journal of Pharmaceutical Research Vol 1, No 1 (2021): Indo J Pharm Res 2021 1(1)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v1i1.2437

Abstract

Nutmeg pulp is one part of the nutmeg plant that contain antioxidant to prevent free radicals in the body. Nutmeg pulp contains secondary metabolites of the flavonoid class which have function as antioxidant. This study was conducted to determine the effect of drying the nutmeg pulp on the level of antioxidant activity using the DPPH method. After measuring the antioxidant activity of wind-dried and oven–dried nutmeg using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method, the results showed that the antioxidant activity (IC50) of wind dry is 116,952 µg/mL and oven dry is 219,2 µg/mL. The result of one-way Anova data analysis obtain p-value (p)
Repellent Activity Test Of Essential Oil Gel Of Cinnamommum Burmanii Bi Leaves Against Aedes Aegypti Mosquitoes Bayuadi Bayuadi; Purwati Purwati; Riong Seulina Panjaitan
Indonesian Journal of Pharmaceutical Research Vol 2, No 2 (2022): Indo J Pharm Res 2022 2(2)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v2i2.4180

Abstract

Cinnamomum burmanni BI leaf is known to have high eugenol content, eugenol able to resist the bite of Aedes aegypti mosquito as a vector of Dengue Hemorrhagic Fever. Research on test of repellent activity of gel oil  Cinnamomum burmanni BI leaf to Aedes aegypti mosquito is done to know its activity as a repellent preparation against Aedes aegypti mosquito. In this research made the gel of essential oil of Cinnamomum burmanni BI leaf with base karbopol 940  made in 3 formula, F1 (7,50%); F2 (15,00%); F3 (30,00%) and use Positive Control repellent supply on the market and contains DEET. The three formulas produce a good gel in terms of physical stability, organoleptic, homogeneity, pH, viscosity, and scattering, but all formulas cause irritation. The test of repellent activity against Aedes aegypti mosquito done for 4 hours with 5 repetitions showed Cinnamomum burmanni BI  leaf oil formula F3 (30,00%) had repellent activity against Aedes aegypti mosquito with high protection 94,01% for 4 hours.
CAFFEIN LEVELS IN GREEN TEA BAGS Riong Seulina Panjaitan; Risty Setyati Ashari; Saiful Anwar; Nurul Asfia; Silvy Widya Rahmi; Marisa Tamara Sari
Indonesian Journal of Pharmaceutical Research Vol 2, No 1 (2022): Indo J Pharm Res 2022 2(1)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v2i1.3513

Abstract

Caffeine is known to have a pharmacological effect, namely as a stimulant for the central nervous system and metabolism, besides that it can be used for treatment in reducing physical overload and can also increase alertness levels. This study aims to determine the caffeine content in 25 grams (10 bags of green tea bags) from 3 different packaging brands. Extraction of caffeine from green tea bags was carried out using the maceration method, and recrystallization of the caffeine content with hot acetone, then titration of ligroin(n-hexane) to obtain pure crystals. The caffeine obtained from 3 samples, namely sample A obtained 0.099% sample B obtained 0.088% sample C obtained 0.094 % and all samples in the safe category did not exceed SNI is 50 mg/serving.

Page 2 of 3 | Total Record : 24

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