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Ophthalmologica Indonesiana
Published by Perhimpunan Dokter Spesialis Mata Indonesia
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 44 Documents
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Search results for , issue "Vol 49 No S1 (2023): Supplement Edition" : 44 Documents clear
HUBUNGAN ANTARA PEMAKAIAN LENSA KONTAK DAN RISIKO BLEFAROPTOSIS DIDAPAT Febianza Mawaddah Putri
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/f7cvsk87

Abstract

Objectives: Contact lenses (CL) wear has been reported to be associated with acquired blepharoptosis. This literature review aims to summarize and evaluate the risk of acquired blepharoptosis in contact lens wearers. Methods: Literature searching was conducted using three online databases including PubMed, Cochrane Library, and Embase. Search terms such as “contact lens”, “ptosis”, and “blepharoptosis” were included. Reference lists of each study were also assessed for potentially relevant sources. Results: Using relevant search terms in various databases, a total of three articles were included in this review. All studies reviewed were single-center retrospective studies. The three studies suggested that wearing contact lens was significantly associated with blepharoptosis. Long-term contact lens wear, ranging from 15 to 34 years, seemed to have a significant effect on the incidence of blepharoptosis. Hard contact lens (HCL) wear has a greater risk for ptosis to occur than soft contact lens (SCL) wear. Conclusion: There is evidence of a clear association between hard or soft contact lens wear and an increased risk of blepharoptosis. Patients wearing contact lenses should be informed of the risk of blepharoptosis, and a history of contact lens wear should be sought in all patients who have acquired blepharoptosis.
KECERDASAN BUATAN UNTUK MATA KECIL: TINJAUAN SISTEMATIS TERHADAP DEEP LEARNING DALAM MENGEVALUASI KATARAK PEDIATRIK Eric Tjoeng; Nur Devina Annisa
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/1ydhv934

Abstract

Background: Pediatric or congenital cataract (CC) is a leading cause of visual impairment and blindness in children worldwide. Deep learning (DL), a subfield of artificial intelligence, has the potential to enhance diagnosis, treatment, and outcomes in various medical fields. Research Objectives: summarize and evaluate the diagnostic and prediction capabilities of DL algorithms for CC. Methods: From 1st February to 25th March 2023, a literature search was conducted in databases such as PubMed, ScienceDirect, EMBASE, and EBSCO, as well as alternative sources such as Google Scholar. Search terms included “pediatric/congenital cataract”, “artificial intelligence", "deep learning", "convolutional neural network", “diagnosis”, "screening", "prediction" and other relevant synonyms. Quality assessment of studies were assessed based on CONSORT-AI and QUADAS-2. Outcomes extracted included accuracy, sensitivity, specificity, and area under the curve (AUC). Results: Out of 69 studies screened, five studies with different study designs, dataset sizes, and type of DL algorithms employed were included in the systematic review. Most studies employed DL to analyze slit-lamp images to diagnose CC, while one study utilized DL to predict existence of CC from several risk factors. In silico, most studies demonstrated high accuracy and validity of DL algorithms in detecting and predicting CC; however, DL algorithm is not as accurate in diagnosing CC when compared to human counterparts. These studies had limited generalizability given the homogenous population. Conclusion: DL shows potential as an adjunct tool for ophthalmologists to improve diagnosis and, therefore, treatment decisions for CC, particularly in remote and underdeveloped regions with limited medical resources.
HUBUNGAN UKURAN PUPIL DENGAN KELAINAN REFRAKSI PADA SINDROM METABOLIK MAUPUN NON SINDROM METABOLIK PADA POPULASI DI DESA KABUPATEN MALANG Kurrotul Aini; Anny Sulistyowati; Wino Vrieda Vierlia
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ha8fm564

Abstract

Purpose: This study aims to assess the relationships between pupil size and refractive errors in both metabolic syndrome and non-metabolic syndrome populations residing in rural areas of Malang. Methods: A descriptive study was carried out in 2019 across three villages in Malang districts. All attending participants underwent a comprehensive ocular examination, including pupil size assessment. Pupil abnormalities were defined as deviations from the normal diameter of 2-4 mm in bright light. Clinically relevant refractive errors included hyperopia (SphEq value ? 0.25 D), myopia (SphEq value ? -0.25 D), and astigmatism (cylinder ? 0.25 D). Blood samples gauged serum fasting glucose, high-density lipoprotein cholesterol, and triglyceride levels. Waist circumference, systolic, and diastolic blood pressure were measured. Metabolic Syndrome diagnosis followed the 2006 International Diabetes Foundation criteria. Participants were categorized into metabolic syndrome and non-metabolic syndrome groups. Results: The examination involved 953 participants, encompassing 944 right eyes and 942 left eyes. For the right eye, 434 eyes showed emmetropia, 252 exhibited myopia, 141 had hyperopia, and 117 presented astigmatism. Pupillary abnormalities were linked to astigmatism, but lacked significance (p = 0.893). The left eye results indicated 444 eyes with emmetropia, 244 with myopia, 138 with hyperopia, and 116 with astigmatism. Correlation with pupillary abnormalities yielded a non-significant p-value of 0.864. Pupil size outcomes in metabolic syndrome (499 eyes) and non-metabolic syndrome (454 eyes) were not significant (p = 0.649). Conclusion: Refractive error does not correlate with pupil size in metabolic syndrome and nonmetabolic syndrome.
INTRAVENOUS METHYLPREDNISOLONE EFFECTS ON RECTUS MUSCLES IN THYROID EYE DISEASE Milzan Murtadha; Agus Supartoto; Purjanto Tepo Utomo; Banu Aji Dibyasakti; Irene Titin Darajati
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/7nrw4309

Abstract

Introduction & Objective: Intravenous methylprednisolone has been used in management of Thyroid Eye Diseases (TED) which was an autoimmune inflammatory disease of the orbital tissues and the eyes. Previous study has shown benefits of intravenous methylprednisolone therapy on TED but there was need of quantitative measure to assess the effect of intravenous methylprednisolone therapy on extraocular rectus muscles. This study aimed to report the effect of high-dose intravenous methylprednisolone pulse therapy on inferior, medial, superior, and lateral rectus muscles and providing data distribution of active TED before and after therapy. Methods: Retrospective analyses were used in the data collection of patients with active Thyroid Eye Disease (TED) underwent high-dose intravenous methylprednisolone pulse therapy regiment 500mg every week for six consecutive weeks at Sardjito Eye Centre between January 2022 and December 2022. Ophthalmological investigation and quantitative computed tomography (CT) scan of the orbit were performed before and after methylprednisolone pulse therapy and demographics data were presented in tables and graphs. Results: This study included 62 eyes of 31 patients (61,3% female) with mean age of 37.8±13.47 years old. The mean thickness of Superior Rectus (SR) muscle before therapy were 4.12±2.20 mm and significantly decreased to 3.70±1.54 mm post therapy. There was no significant difference in delta mean Inferior Rectus (?IR) -0.18±1.69 (p=0.381), Medial Rectus (?MR) -0.34±1.68 (p=0.116), and Lateral Rectus (?LR) -0.33±1.94 (p=0.188) Conclusion: The treatment of Thyroid Eye Disease (TED) with high dose intravenous corticosteroid is safe and effective in reducing extraocular muscle tissue thickness with minimal side effects. Keywords: Thyroid Eye Disease, Extraocular Muscle, Intravenous Methylprednisolone Therapy.
OPTICAL COHERENCE TOMOGRAPHY PREDICTS VISUAL RECOVERY OF PATIENTS WITH PITUITARY ADENOMA FOLLOWING SURGERY IN DR KARIADI HOSPITAL,SEMARANG Galuh Yulieta Nitihapsari; Riski Prihatningtias
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tfztq864

Abstract

Introduction and Objective: The characteristics, symptoms, and clinical manifestations of pituitary adenoma in Indonesia have not been widely studied. In 26 patients undergoing pituitary surgery at Dr. Kariadi Hospital, we compared visual acuity pre-operative and post-operative from normal and thin optical coherence tomography (OCT) of the retinal nerve fiber layer (RNFL) and ganglion cell layer-internal plexiform layer (GCL-IPL). Method: A retrospective study of the medical record from January 2020 to December 2022 was done. 21 of the 26 patients had surgery by the transsphenoidal route and the rest by craniotomy. All patients had macroadenoma (tumor size >1cm) and were histologically confirmed. Visual acuity before and after surgery was evaluated along with the patient’s OCT value. Result: The thinner pre-operative RNFL thickness was associated with worse visual acuity (VA). Patients with normal RNFL had a median VA of 20/200 while those with thin RNFL had to count their fingers (CF). The patients with normal pre-operative RNFL had a significant improvement in median VA after surgery, from 20/200 to 20/32 (p=0.022), whereas the patients with thin RNFL did not improve (CF to CF, p=0.026). The patients with normal pre-operative GCL-IPL had non-significant improvement in median VA after surgery from CF to 20/20 (p=0.505), also the patients with thin GCL-IPL from CF to 20/200 (p=0.151). Conclusion: The visual recovery after pituitary adenoma surgery is likely to be predicted by pre-operative OCT RNFL. Patients with normal RNFL thickness show an increased tendency in visual recovery after surgery. Keywords: Optical coherence tomography , visual acuity, pituitary adenoma
Hasil Tindakan Bedah Implantasi Glaucoma Drainage Device pada Pasien Glaukoma Refrakter di RSUP dr Sardjito Yuandani Saputra; Krisna Dwi Purnomo Jati; Tatang Talka Gani; Retno Ekantini
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ak6fah94

Abstract

Introduction: Glaucoma drainage device (GDD) implantation was an effective surgical procedure in treating uncontrolled intraocular pressure (IOP) of glaucoma patients in certain complicated conditions. GDD implants were classified into valved and non-valved in which its surgical outcomes in different types of device and various etiologies were not similar. This study aimed to evaluate the surgery outcomes of GDD implantation in patients with refractory glaucoma at Sardjito General Hospital. Methods: All 12 eyes of 11 patient’s medical records who underwent GDD implantation during 2022 at Sardjito General Hospital was reviewed. Baseline data include age, gender, eye laterality, type of glaucoma, IOP and visual acuity. The IOP and visual acuity (LogMAR) were measured at week 1, month 1, 2 and 3. Type of GDD implants, postoperative glaucoma medications, complications and need for further glaucoma surgery were documented. Results: The mean IOP at baseline was 44 ± 14.2 mmHg with 3.4 ± 0.6 glaucoma medications. It decreased after surgery into 19.1 ± 11.2 mmHg (p=0.003) at 3 months follow up with 0.7 ± 1.7 (p=0.002) glaucoma medications. The mean initial visual acuity was 1.9 ± 0.6 and changed insignificantly to 1.7 ± 0.8 (p=0.624) at last follow up. Six eyes (50%) were implanted with valved implant. The most common early postoperative complications were recurrent high IOP (4 eyes, 33.3%) associated to ripcord of non-valved implant (p=0.025). Five eyes (41.7%) needed additional surgery related to non-valved implant type (p=0.003). Conclusion: GDD implantation especially valved type appears to be safe and effective surgical option in treating refractory glaucoma patients Keywords: Glaucoma drainage device, refractory glaucoma, glaucoma surgery, intraocular pressure
Swollen Disc in Children : Diagnostic Approach Riski Prihatningtias
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/y6tekc65

Abstract

Swollen disc is a clinical sign of eye disease, neurological or systemic. It happened because of the increase in intracranial. Some of the conditions that cause swollen disc are optic neuritis, optic neuropathy, retinal vein occlusion, papilloedema, or pseudo-disc swelling (e.g drusen). In children, the incidence of swollen discs differs from that in adults. Diagnosis can be made using OCT (Optical Coherence Tomography), ocular ultrasound, VEP (Visual Evoked Potential) and MRI (Magnetic Resonance Imaging) of the orbit and head
English: English Muhammad Insanul Kamil Rery; Rodiah Rahmawaty Lubis; Bobby Ramses Erguna Sitepu
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ztxmtb75

Abstract

Introduction and Objective: Ocimum sanctum extract (OSE) has been shown to have antioxidant, anti-inflammatory, and antibacterial properties which are responsible for wound healing. This study aims to analyze the effect of 5%, 10%, and 15% OSE ointment on changes in collagen density and fibroblast count in Wistar rats with partial-thickness palpebral laceration. Methods: Laboratory experimental study with randomized post-test only control group design. The subjects were 30 rats divided into 5 groups: The placebo; Gentamicin 0.3%; OSE 5%; OSE 10% and OSE 15% group. The intervention was administered 2 times/day for 4 days. On the fifth day, the palpebral tissue was obtained to make histopathological preparations and to observe the collagen density and fibroblast count. Data were analyzed using Mann-Whitney, One-Way ANOVA, Kruskal Wallis, and Tamhane test. A p-value <0.05 was assigned to the statistically significant. Results: The placebo group revealed loose collagen tissue and OSE 15% and gentamicin group revealed dense collagen tissue. The low fibroblast count was in the gentamicin and OSE 15% group and the highest fibroblast count was in the placebo group with a mean of 19.77±3.29; 22,67±0,73 and 60.9±10.66 cells, respectively. There was a significant difference (p<0.001) in the collagen density and the fibroblast count based on the treatment groups. Posthoc tests revealed differences in the collagen density level and the fibroblast count between the placebo and the whole group. Conclusion: There was a significant difference between placebo and all groups of collagen density changes and fibroblast count. There was no difference between OSE 15% and gentamicin both microscopically and statistically. Keywords: Ocimum sanctum L, Extract of Ocimum sanctum L, partial-thickness palpebral laceration, fibroblast cell count, collagen density
COMPARISON OF SITA STANDARD 24-2 WITH SITA FASTER 24-2C PROGRAM ON HUMPHREY FIELD ANALYZER IN ASSESSING VISUAL FIELD DEFECTS OF GLAUCOMA PATIENTS Nuzul Rianti; Karmelita Satari; Andika Prahasta; R. Maula Rifada; Sonie Umbara
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/a4syph39

Abstract

Introduction: Periodical perimetry examination to detect and determine the rate of glaucoma progression continues to be a challenging task, because it depends on many factors. Besides, there is now a paradigm shift which central visual field defects occur earlier. SITA Standard (SS) 24-2 is the clinical standard for glaucoma examination, but there were studies reporting on the prevalence of central visual field defects not detected. SITA Faster (SFR) 24-2C was developed to address current shortcomings, but the performance has yet to be formally and independently assessed. Objective: To compare the global indices (Mean Deviation, Pattern Standard Deviation, Visual Field Index) and test duration between SS 24-2 and SFR 24-2C program. Methods: This is an analytical observational study with a cross-sectional design. Subjects aged >18 years who diagnosed with glaucoma and whose visual fields unaffected by other condition besides glaucoma were included. All subjects underwent testing of both programs. Results: This study was conducted in 94 eyes of 66 patients. Comparison of global indices and test duration between the two programs was carried out by the Wilcoxon test. The mean results of MD and PSD global indices were not significantly different, however there was a difference in the mean VFI of 1.5% between the two programs. The test duration of SFR 24-2C was 55.03% faster. Conclusion: There was no significant difference in the MD and PSD global indices, but there was a significant difference in the VFI, as well as the test duration between the two programs.
SUCCESS RATE OF GLAUCOMA DRAINAGE DEVICE IMPLANTATION IN KARIADI GENERAL HOSPITAL SEMARANG 2020 – 2022 Rina Apriliana; Fifin L. Rachmi; Maharani Maharani
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/zz8h4706

Abstract

Introduction: Glaucoma is a leading cause of irreversible blindness, and implantation of drainage devices is an effective treatment option for patients with advanced glaucoma. The purpose of this study was to investigate the success rate of glaucoma drainage devices implantation in Kariadi Hospital. Methods: This was an observational analytic study with a retrospective design. All patients who received Virna implantation between January 2020 and December 2022 were included. Intraocular pressure (IOP) examination was performed at the baseline and at the first day, at the seventh day, at the first month, and at the third month after surgery. The success rate was divided into three groups: complete success if IOP was <21mmHg without medication, qualified success if IOP was <21mmHg with medication, and failure if IOP was >21mmHg with medication. Results: This study included 42 patients (42 eyes) with an average age of 43.3 years. There were 16 male (38%) and 26 female (62%) patients in the group. From these patients, 11 (26.2%) had primary glaucoma and 31 (73.8%) had secondary glaucoma. There was a significant decrease in IOP from preoperative measurement (37.1±10.1mmHg) compared to IOP on the first day (13.0±6.0mmHg), on the seventh day (15.4±3.8mmHg), on the first month (18.2±4.4mmHg), and on the third month (23.4±8.9mmHg) after surgery (p<0.05). At three-month follow-up, the complete success was 14.29%, the qualified success was 50%, and the failure was 35.71%. Conclusion: Glaucoma drainage device implantation was found to successfully reduce IOP in patients with advanced glaucoma. The qualified success rate was higher than complete success rate, suggesting that some patients may require medication to achieve target IOP levels.

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