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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 7 Documents
 1 
Search results for , issue " Vol 41, No 02 (2009)" : 7 Documents clear
The Role of Cervical Erosion on Vaginal Colonization of Candida sp. Study on the Intrauterine Contraceptive Device Users in Puskesmas Depok I Sleman Satiti Retno Pudjiati, Erni Setyawati, Fajar Waskito
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Candida sp is an opportunistic pathogenic yeast causing clinical diseases such as vulvovaginal candidiasis (VVC) under certain circumstances. Availability of erythrocytes in the vagina, as in cervical erosion, creates an ideal niche for yeast possessing erythrocyte-binding surface receptors to enhance colonization of Candida sp. Objective: To compare the number of vaginal Candida sp colonies among IUD users with and without cervical erosion. Methods: It was a cross-sectional study involving 45 IUD users. Subjects were classified into cervical erosion group and without cervical erosion group, who underwent vaginal lavage to obtain vaginal fluid samples. Candida sp were grown by inoculating 0.1 ml of vaginal fluid samples into CEA culture media and incubated at 25°C-30°C for 48 hours. Candida sp would grow as round and smooth colonies in blackish-brown color. The numbers of colonies (cfu/ml) in each CEA disk were measured manually, and multiplicated with the factors of dilution. Data were numeric variables, and analyzed with Students t-test. Results: Average number of Candida sp colonies in the group with cervical erosion was 154.25:t 102.61 cfulml, while that in the group without cervical erosion was 47.00:t 39.08 cfulml. Conclusion: Average number of Candida sp colonies in IUD users with cervical erosion was significantly higher than in IUD users without cervical erosion (p < 0.05). Key words: cervical erosion - Candida sp - VVC - yeast possessing erythrocyte-binding receptors -IUD
Body Composition in Javanese Adult: Some Anthropometric Dimensions Related to Body Fat Hastuti, Janatin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Body composition is an integral component of entirely health and physical fitness. Measurement of fat component in assessing body composition is necessary on account of its relation to several health risks. Some anthropometric measurements such as waist to hip ratio (WHR), waist and hip circumferences, skinfold thickness, and sagittal abdominal diameter are demonstrated to be valuable for evaluating body composition, and further for identifying some health risk factors. Objectives: This study is addressed to know body composition and some anthropometric measurements related to percent body fat in Javanese adults living in Yogyakarta province. Methods: As many as 201 (98 males and 103 females) Javanese adults living in Yogyakarta province, aged 18 to 65 years were entrolled in this study. Measurements of body weight, height, waist, abdominal, and hip circumferences, sagittal abdominal diameter, and total skinfold thickness of triceps, biceps, subscapular, suprailiac were performed on the subjects. Body composition was assessed based on those measurements included percent body fat, body density, and skeletal muscle mass. Body mass index and waist-to-hip ratio were determined and categorized. The data then were analysed using independent Hest, Pearson correlation of product moment, linear regression, and chi-square test. Results: The result indicated that in a general sense, Javanese adults in Yogyakarta province had thin to medium body constitution and risk factor categorized of low to medium risk for males and medium to high risk for females. Javanese adult males were considerably heavier, taller, had greater means of body density, WHR, and muscle mass. By contrast, Javanese adult females were significantly higher in BMI, percentage of BF, and hip circumference. Statistically, there is no significant difference in total skinfold, abdominal circumference, and SAD, however, females indicated to a certain greater than the males. In the same manner, males had larger waist circumference. Conclusions: All of anthropometric dimensions including skinfold thickness, body density, waist circumference, abdominal circumference, WHR, sagittal abdominal diameter, and muscle mass are strongly correlated with body composition assessed with BMI and % BF. However, associations with BMI are fairly better than those of with percentage of BF. Among those measurements WHR showed the weakest correlation. There was also a different tendency in the power of correlation between anthropometric dimension with BMI and percentage of BF in males and females. Yet, all the measurements were supposed to be performed to incorporate evaluation on human body composition. Key words: body composition - Javanese adults - anthropometric measurements - percentage of body fat.
The Comparison of Hydration Effect of 1% Aloe Vera Extract Cream and 10% Urea Cream as Moisturizer for Non Dermatotic Skin Fajar Waskito, Laily Noor Qomariah, Sunardi Radiono,
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Universitas Gadjah Mada

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Background: Xerotic or dry skin is a condition with manifestation of scaly, coarse skin with itchy sensation. Moisturizers have been used as treatment to alleviate xerotic skin. Aloe vera is a traditional medicinal plant which has been used as skin moisturizer for a long time, however, the hydration effect of this material had not been studied. Urea is a humectant material that has been widely used as moisturizer. Objective: This study was aimed to compare the hydration effects of 1 % Aloe vera extract cream with 10% urea cream as moisturizer for non-dermatotic dry skin. Methods: This research was a single-blinded randomized controlled trial. Thirty research subjects who met inclusion criteria were given 2 types of interventions (1 % Aloe vera extract cream or 10% urea cream). Randomization was conducted to determine which cream was applied on the subjects lower arm. Cream was given as a single application. Evaluation of stratum corneum hydration level was conducted objectively using corneometer instrument: before application, 30 minutes, 1 hour, 2 hours, 3 hours and 4 hours after single application. Data of the two groups were analyzed with paired t-test. Results: There was no significant difference of stratum corneum hydration level between 1 % Aloe vera extract cream treatment and 10% urea cream at each time of measurement (p > 0.05). Conclusion: 1 % Aloe vera extract cream showed similar or equivalent hydration effect with 10% urea cream as moisturizer for non-dermatotic dry skin. Key words: aloe vera - urea - skin moisturizer - skin hydration.
The Difference of High Sensitivity-C Reactive Protein in the Diabetic Patient with depression and Diabetic Patiens without Depression Hamzah Shatri, Deddy N.W.Achadiono, A. Siswanto, E. Mudjaddid
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Both depression and diabetes mellitus have been related to a higher risk of developing coronary heart disease. Inflammation may be important in the pathogenesis of atherothrombosis. There are many markers of inflammation, one of them is high sensitivity-C reactive protein. Objective: To determine the difference of high sensitivity-C reactive protein in the diabetic patients with depression and in the diabetic patients without depression. Methods: This study used cross-sectional design and examined 64 diabetic patients, aged 30-60 years old. The patients were divided into two groups, Le. with and without depression group.We measured depression using the DSM IV. The diagnosis of diabetes mellitus used PERKENI criteria 2006. We measured the serum concentration of CRP with a high sensitivity assay. Other measured factors included gender, marital status, occupation, blood glucose, HbA 1 c, body mass index, smoking and duration of diabetes. The association between hyperglycemia and hs-CRP were also studied. Results: There were 32 diabetic patients with depression and 32 diabetic patients without depression. Body mass index were corelated with depression in diabetic patients (p = 0.008) but the other factors such as gender, age, marital status, occupation, blood glucose, HbA 1 c, duration of diabetes were not corellated with depression in diabetic patients (p > 0.05). The mean of hs-CRP consentration was higher in diabetic patients with depression (5183.44:t3974.66 vs 2103,17:t1502.94 mg II, p=0.001) than in diabetic patients without depression. There was no association between blood glucose control (HbA 1 c) and hs-CRP concentration. Conclusion: High sensitivity-C reactive protein concentration was higher in diabetic patiens with depression compared with diabetic patients without depression.Key words: hs-CRP - with and without depression diabetes mellitus type II
The Efficacy of the Combination of 2% Lidocaine and 0,5% Bupivacaine as Preemptive Analgesia for post-operative pain in vitrectomy with or without scleral buckle under genral anasthesia Angela Nurini Agni, Marlyna Afifudin, Hartono,
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Background: Post-operative pain is one of the main problems in the surgical services so that analgesia is very much needed, even intravenously given. The concept of preemptive analgesia in surgical intervention is the provision of analgesia before the occurence of nociceptive stimulus. One of the agents for providing preemptive analgesia is local injection is local injection with local anasthetic, single or in combination. Objective: This study was aimed to evaluate the efficacy of combination of lidocain and bupivacain as preemptive analgesia in vitrectomy with or without sclera buckle under general anesthesia. Methods: Twenty eight patients who were scheduled for vitrectomy were included in this study. The patients were randomly classified into two equal groups. The surgery was conducted under general anesthesia for both groups, but in Group 1, subtenon anesthesia with local anesthetic was given as preemptive analgesia after induction anesthesia and before the start of surgery. Pain intensity was the primary outcome of this study. The pain intensity was measured in 3 hours and 24 hours after surgical procedure. Results: The baseline characteristics between the two groups were similar. The pain intensity was lower in the treatment group, but the difference was not statistically significant (1.00:t 1.71 vs 1.50:t 2.16, p = 0.109). The proportion of pain-free patients were similar between the two groups in 3 hours after procedure (65% vs 65%, p = 1.00). The proportion of pain-free patients were higher in the treatment group in 24 hours after procedure (100% vs 73%, p = 0.222, Fishers Exact Test}. The subtenon injection procedure was safe. There was insignificant difference in the incidence of side effects between the 2 groups. Conclusion: This study did not show any additional benefit of subtenon injection for vitrectomy. The pain intensity was similar between two groups. There were no increases on side effects after the procedure. Key words: vitrectomy - local anesthetic - post-operative pain - preemptive analgesia
The Role of Hearing Aids use on Reading Ability in Deaf Students Djoko Rianto, Bambang Udji
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Introduction: Reading is a very complex process, which includes the cognitive process, initialized by visual analysis and letter transformation into vocabulary form, word identification by letter sound mapping, correlating words and interpretation. Deafness causes difficulties in acquiring language information via hearing process thus inhibiting a successful conversation process. Hearing aids can amplify sound information to the auditory organs. Objective: To know the effect of hearing aids on deaf students. Methods: A historical cohort design was done. The reading ability of 35 deaf students with hearing aids who received early education were compared to those without hearing aids. The variables measured included age, age of school enrollment, length of studies, degree of deafness, sex, parental educational level. Results: Regression analysis showed that hearing aids plays a role to significantly increase reading ability statistically (p: 0.006; OR: 10.197; 95% CI: 1.939-53.628) compared to students without hearing aids, besides the length of studies variable (p: 0.002; OR: 38.250: 95% CI: 3.739-391.361). Conclusion: This study concluded that the use of hearing aids significantly play a role to increase reading ability in deaf students who receive early education. Key words: hearing aids - deaf student - reading ability.
The Relation Between the Expression of latent Membrane Protein-1 Sofia Mubarika H, Soeripto, Murtono C,
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Background: In vitro studies reveal that LMP1 induces the expression of many factors for invasion and metastasis. Objective: The aims of this study were to investigate the role of LMP1 expression on the status of Nand M that take place either directly or sequentially through its relation with the expression IL4, IL6. IL 10. IFN-gamma. Gran2yme B and with protease MMP2. MMP9. either in the serum or in the tumour tissue. Methods: Forty one 41 EBER-RISH confirmed NPC cases with parallel serum were used for this study. Immunohistochemistry was used to study the expression of proteins in the tissue. The serum level of proteins were determined with ELISA. Statistical analysis used Lisrel 8.50. Results: No correlation between the expression of LMP1 with the status of Nand M of the tumour either directly or that sequentially took place through the expression of the cytokines and MMPs either in the tumour tissue or the serum level. The serum level of MMP9 was correlated with the serum level of IL6, the status of N. and the expression of IL 10. Status N was correlated with serum level of MMP2. Conclusion: There is a process that sequentially took place through the increase of the cytokines. MMPs, either in the tumour tissue or serum level and N. M status. LMP1 expression was not involved in the process. Key words: NPC - metastasis - MMP - cytokine

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