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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 14 Documents
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Search results for , issue "Vol 25, No 01 (1993)" : 14 Documents clear
Neurotic tendency of smokers Soewadi, Soewadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The harniful health effects of tobacco smoking have been reported by many experts. Death rates are unifomily higher among smokers than among non-smokers, in both sexes and whatever the age at death. Cigarette smoking is also considered to be responsible for the great majority of cases of lung cancer. There is evidence that the influence of smoking in ischaemic heart disease is not only independent, but also synergistic with other risk factors such as hypertension and high blood cholesterol. Surveys in many countries show that smokers cough more than non-smokers and produce more sputum. Cigarette smoking acts independently and synergistically with other risk factors contributing to bronchitis.Many experts agree that the smoking problem is now a worldwide epidemic and causing serious diseases. Therefore, studying the problem associated with tobacco should include, specifically the harmful health effects of smoking.The study was carried out in Yogyakarta among senior high schools student. The aim of the study is to test the hypothesis that there is a relationship between neurotic tendency with smoking. Randomized sampling method were done for the analytic-descriptive design of the study.Results showed that there is a significant difference between group of smokers and non-smokers according to the tendency of neurosis (p<0.05). Results also showed that there is a correlation between the tendency of neurosis and smoking (Contingency-Coeff.=0.44)Key Words: smoking - smoker prevalence - smoker relatives - neurosis - psychiatric intervention
Pentingnya Kedokteran Ekologis Anonim, Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci: Kedokteran - Ekologi
Antifilarial Activity of Diethylcarbamazine in Brugia Pahangi Aedes Togoi Model Infection Sugeng Juwono Mardihusodo, Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Sejak tahun 1947 dietilkarbamasin (DEC) diketahui khasiatnya sebagai antifilarial. Penelitian lanjutannya :ebih banyak mengarah kepada khasiatnya sebagai mikrofilarisida dan makrofilarisida pada Venebrata. Kejelasan aktivitas DEC terhadap stadia perkembangan cacing filaria dalam nyamuk Vektomya sangat sedikit diketahui, yang sebenamya juga penting untuk mengungkap makna obat itu dalam pengendalian penularan filariasis. Penelitian ini bedujuan untuk mengungkap lebih rind tentang daya DEC sebagai filarisida pada nyamuk Acdcs togoi yang diinfeksi dengan Brttgia pahangi.Penelitian dilaksanakan dengan memberikan pakan secara langsung kepada Ae. togoi yang dikolonisasi dengan larutan DEC dalam air sukrose 10% dengan konsentrasi 200, 100, 50 dan 0 mg%. Angka modalitas (AM), angka infeksi (Al), angka infektif (Alm), jurnlah larva per nyamuk terinfeksi (JUN), jumlah larva infektif per nyamuk terinfeksi (JL1PN), perlyebaran larva B. pahangi dalam tubuh nyamuk, dan ukuran (panjang badan) larvae, setelah nyamuk Ae. togoi dikolonisasi selama 12 hari setelah pemberian pakan darah infeks dan kucing yang terinfeksi B. pahangi, di tetapkan.Pedambahan AM nyamuk Ae. togoi yang tanpa maupun dengan infeksi B. pahangi tidak bermakna, dan tidak bergantung kepada konsentrasi DEC, menunjukkan bahwa DEC tidak bersifat insektisidal. Perbedaan di antara AM nyamuk tanpa dan dengan infeksi filarial diduga karena daya merusak filaria parasit selama perkembangan dan migrasi dalam tubuh nyamuk.Al dan Aln nyata menurun pada had ke 12. Larva H (U) B. palzangi masih ditemukan dalam tubuh Ae. togoi yang diberi pakan larutan DEC selama 12 hari; hal ini mengesankan bahwa DEC menghambat perkembangan sebagian larvae B. pahangi. Selama 12 hari persentase larvae B. pahattgi di bagian kepala nyamuk Ae. togoi nyata lebih rendah daripada yang pada nyamuk pembanding; hal ini menunjukkan hahwa DEC juga menghambat migrasi sebagian larvae filaria. Disimpulkan hahwa DEC nyata berIchasiat parsial sebagai anti filarial pada infeksi model B. pahangi - Ae. togoi.Key Words: diethylkarbamazine B. pahangi Ae. togoi insecticidal effect inhibitory effect
Satu Generasi Telah Lewat Anonim, Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci: Redaktur
Post-traumatic syndrome Harsono, Harsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Post-traumatic syndrome is a constellation of symptoms that developed in a person usually following a relatively minor head injury. It can grossly in capacitating for the patient and can develop a chronicity that makes it almost a change in personality. The commonest symptoms are headache, and dizziness; but impairment of sleep, decreased concentration and libido, anxiety, depression, irritability and sensitivity to noise are also seen.The cause of the syndrome is a ,contentious issue. The question whether it is primarily of psychological or organic origin remains unanswered in many cases. Organic or phychogenic, each symptom by itself is of little consequence, but in combination they may be disabling enough to prevent useful employment. Furthennore, the development of the syndrome of any head injury is not easy to be predicted.Key Words: post-traumatic syndrome headache neurotic personality depression amnesia
The involvement of mesolimbic dopaminergic system in ovulation in rat (Rattus norvegicus) Soedjono Aswin, Soedjono Aswin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Mesolimbic dopaminergic system involvement in the ovulatory process was studied in the immature superovulation rats (Rartus norvegicus). Nucleus ventralis tegmenti (NVT, area A-10) was neurochemically lesioned by stereotaxically placed injection of I Vg 6-hydroxydopamine (6-OHDA) into the brain. Ovarian weight, frequency and rate of ovulation, the number of corpora lutea found in the ovaries, and histologic features of the ovaries were observed.The results of the present experimental study indicate that neurochemical lesion of NVT with 6-OHDA produced a significant (p<0.01) decrease in the ovarian weight, as well as the ovulation rate and the number of corpora lutea found in the ovaries, compared to the shank-operated control and normal control groups. The frequency of ovulation, however, was not affected; it means that all groups of immature rats underwent ovulation. It is interesting to note that the ovulation rate of the lesioned group was suppressed (but not prevented) by about 60% as shown by the decrease in the number of corpora lutea found in the ovaries and in the number of ova per ovulation. Histologic features of the ovaries of the lesioned group performed an inhibition of follicular development as evidenced by the characteristic :features of the induction of polycystic degeneration, beside the decrease in the number of corpora lutea found in the ovaries.It is concluded that mesolimbic dopaminergic system specifically plays a significant role in the regulation of ovulatory process in the immature superovulation rats. Based on the present data it is hypothesized, that lesioning mesolimbic dopaminergic system chemically with 6-OHDA resulted in significant decrease in luteinizing hormone releasing hormone (LHRH) released from hypothalamus, which in turn ensued the decrease in the tonic release of luteinizing hormone (LH), which is known responsible for the development of the ovarian follicles; but it seems that there is a slight suppression in the pulsatile release of LH, which is responsible for the initiation of ovulation.Key Words: nucleus ventralis tegmenti - mesolimbic dopaminergic systenm - 6-hydronydopanine -    ovulation - Rattus riorvegicus
Breast milk, weight loss and hyperbilirubinemia in fitllterm newborn infants in the first week of life Achmad Surjono, Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

The objectives were to find out the proportion of hiperhilinthinemia in term of breast-fed newborn infants, the figure of their weight loss and any significant difference in weight loss between hyperbilirubinemic group as compared with control.The subjects consist of a total of 210 singleton full-term newborn babies delivered in Dr. Sardjito Hospital from January 1 to June 30, 1992, with 5 minute Apgar score more than six and on permission of the mothers.The serum total bilirubin (TB) and unbound bilirubin (UB) were measured on day 3 and 5. TB concentration was measured spectrophotometrically and UB level was determined by peroxidase oxidation method using UB-analyzer, an automated micromethod. Body weight and first week conditions of the infants were recorded daily. Mean (± SD) TB and UB values in the third day were 10.30 ± 3.42 mg% and 0.24 ± 0.16 p.g%, respectively. The proportion of hyperbilirubinemia was 11.9%, in whom 44% received phototherapy (UB level 0.5 pg%). The mean weight loss (%) was 3.95 ± 1.84: No statistically significant difference on weight loss was found between hyperbilinthinemic and control group (p > 0.05).Hyperbilirubinemia in breast-fed term newborn infants can be considered a minor problem. Considering the benefit of mother milk, in particular for exclusive breast feeding, temporary cessation of breast feeding is not needed. On the contrary, more frequent suckling is advised with a close observation of UB levels.Key Words : breast feeding fulltenn infants hyperbilirubinemia unbound bilirubin weight loss
Satu Generasi Telah Lewat Anonim Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci: Redaktur
The involvement of mesolimbic dopaminergic system in ovulation in rat (Rattus norvegicus) Soedjono Aswin Soedjono Aswin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Mesolimbic dopaminergic system involvement in the ovulatory process was studied in the immature su'perovulation rats (Rartus norvegicus). Nucleus ventralis tegmenti (NVT, area A-10) was neurochemically lesioned by stereotaxically placed injection of I Vg 6-hydroxydopamine (6-OHDA) into the brain. Ovarian weight, frequency and rate of ovulation, the number of corpora lutea found in the ovaries, and histologic features of the ovaries were observed.The results of the present experimental study indicate that neurochemical lesion of NVT with 6-OHDA produced a significant (p<0.01) decrease in the ovarian weight, as well as the ovulation rate and the number of corpora lutea found in the ovaries, compared to the shank-operated control and normal control groups. The frequency of ovulation, however, was not affected; it means that all groups of immature rats underwent ovulation. It is interesting to note that the ovulation rate of the lesioned group was suppressed (but not prevented) by about 60% as shown by the decrease in the number of corpora lutea found in the ovaries and in the number of ova per ovulation. Histologic features of the ovaries of the lesioned group performed an inhibition of follicular development as evidenced by the characteristic :features of the induction of polycystic degeneration, beside the decrease in the number of corpora lutea found in the ovaries.It is concluded that mesolimbic dopaminergic system specifically plays a significant role in the regulation of ovulatory process in the immature superovulation rats. Based on the present data it is hypothesized, that lesioning mesolimbic dopaminergic system chemically with 6-OHDA resulted in significant decrease in luteinizing hormone releasing hormone (LHRH) released from hypothalamus, which in turn ensued the decrease in the tonic release of luteinizing hormone (LH), which is known responsible for the development of the ovarian follicles; but it seems that there is a slight suppression in the pulsatile release of LH, which is responsible for the initiation of ovulation.Key Words: nucleus ventralis tegmenti - mesolimbic dopaminergic systenm - 6-hydronydopanine -    ovulation - Rattus riorvegicus
Breast milk, weight loss and hyperbilirubinemia in fitllterm newborn infants in the first week of life Achmad Surjono Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.053 KB)

Abstract

The objectives were to find out the proportion of hiperhilinthinemia in term of breast-fed newborn infants, the figure of their weight loss and any significant difference in weight loss between hyperbilirubinemic group as compared with control.The subjects consist of a total of 210 singleton full-term newborn babies delivered in Dr. Sardjito Hospital from January 1 to June 30, 1992, with 5 minute Apgar score more than six and on permission of the mothers.The serum total bilirubin (TB) and unbound bilirubin (UB) were measured on day 3 and 5. TB concentration was measured spectrophotometrically and UB level was determined by peroxidase oxidation method using UB-analyzer, an automated micromethod. Body weight and first week conditions of the infants were recorded daily. Mean (± SD) TB and UB values in the third day were 10.30 ± 3.42 mg% and 0.24 ± 0.16 p.g%, respectively. The proportion of hyperbilirubinemia was 11.9%, in whom 44% received phototherapy (UB level 0.5 pg%). The mean weight loss (%) was 3.95 ± 1.84: No statistically significant difference on weight loss was found between hyperbilinthinemic and control group (p > 0.05).Hyperbilirubinemia in breast-fed term newborn infants can be considered a minor problem. Considering the benefit of mother milk, in particular for exclusive breast feeding, temporary cessation of breast feeding is not needed. On the contrary, more frequent suckling is advised with a close observation of UB levels.Key Words : breast feeding fulltenn infants hyperbilirubinemia unbound bilirubin weight loss

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