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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 12 Documents
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Search results for , issue "Vol 54, No 4 (2022)" : 12 Documents clear
Effect of hormonal contraceptives on the ocular surface and the tear film Muhammad Syauqie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202205

Abstract

Dry eye syndrome (DES) is a common multifactorial disease of the tears andocular surface associated with sex hormones. Hormonal contraception is arisk factor for DES, but its relationship with DES exacerbations in womenof childbearing age is still unclear. This study aimed to evaluate changesof the tear film and ocular surface of young women using the hormonalcontraceptive agent. It was a case-control study involving 56 healthywomen aged 20 to 45 y.o. Subjects was divided into two groups i.e. thehormonal contraceptives group and the control group without hormonalcontraceptive. Subjects were interviewed with the ocular surface diseaseindex (OSDI) questionnaire. Tear secretion and tear stability were measuredusing Schirmer’s I test and fluorescein tear break-up time test (TBUT).Ocular surface impression cytology with cellulose acetate filter paper wastaken from inferonasal bulbar conjunctiva and was stained with periodicacid- Schiff (PAS) and counterstained with hematoxylin and eosin (HE). Nosignificantly decrease in tear secretion and tear stability in the hormonalcontraceptives group compared with the control groups was observed (p >0.05). However, a statistically significant decrease in goblet cell density andconjunctival epithelium metaplasia was observed, where 25% of the hormonalcontraceptives group had an abnormal impression cytology result comparedwith the control group (p<0.05). The hormonal contraceptives group also hada higher OSDI score than the control group, although it was not statisticallysignificant (p> 0.05). The hormonal contraceptives group had a signifificanteffect on the ocular surface in which it induced squamous metaplasia andinflflammation of conjunctival cells and the reduced number of goblet cellsp<0.05). The slightly decreased tear film volume and stability accompaniedby an increase in OSDI score found in the hormonal contraceptives groupsupport the possibility of hormonal contraceptive use as one of the riskfactors in the occurrence of dry eye syndrome.
A report of two cases of type 2 diabetes mellitus (T2DM): happy and longevity Hemi Sinorita; Sri Sutarni; Abdul Gofir
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202211

Abstract

Chronic hyperglycemia in patients with type 2 diabetes mellitus (T2DM) is associated with the development of complications and the increase of risk of mortality. Patients with T2DM have a shorter life expectancy than non-diabetic population. It is attributed to cardiovascular disease, stroke, renal disease, and infection. Depression secondary to T2DM worsens the quality of life. On the contrary, positive emotions correlated strongly with long life expectancy. A number of mechanisms might explain this correlation. We reported two geriatric patients over 80 y.o. with T2DM comorbidity for more than 20 years. Discussion point of these cases is the subject’s longer life span compared to the average diabetic patient’s life expectancy and great quality of life despite the disease burden of chronic hyperglycemia in T2DM and cardiovascular risk.
Decreasing of hand colonization and sterility of refill antiseptic in Dr. Yap Eye Hospital, Yogyakarta Briliana Nur Rohima; Syarah Rysty; Ulupi Rina Hapsari; Palupi Dwi Astuti
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202201

Abstract

Dr. Yap Eye Hospital, Yogyakarta uses aseptic gel containing 70% ethyl alcohol to refill antiseptic containers during times of antiseptic scarcity. The study aimed to evaluate the effectiveness and sterility of the refill antiseptics in reducing the number of colonization on the hands of nurses. It was a quasi-experimental using pre- and post-control groups design involving 56 nurses who used antiseptics in a bottle sterilized by plasma device (plasma bottle) compare to those washed using detergent (detergent bottle) before being refilled. Sterility tests were performed every two wk for up to two mo. Colonization pre and post hand hygiene practices were determined as an efficacy test and compared using the Mann-Whitney test in STATA 14. Antiseptic in plasma bottles remains sterile until the week8th since refilled, longer than detergent bottles (6th weeks). The pre-handrub colorizations were 0.04-16.92 CFU/cm2 and decreased significantly post-handrub to 0.00-3.08 CFU/cm2 (p<0.0001). Significant decrease pre- vs post-handrub colonization was observed in usage of detergent bottle (0.04-31.04 vs 0.00-10.48 CFU/cm2, p=0.0007). There was no significant difference in ∆ colonization for two bottles (0.40-15.76 vs 0.04-30.92 CFU/cm2, p=0.8790). In conclusion, antiseptic in the plasma bottle remains sterile longer than in the detergent bottle since refilled. Both of them are equally effective in reducing colonization after handrub activity.
Evaluation of clinical pathway implementation and clinical practice guidelines in the management of deep neck abscess (DNA) at Dr. Sardjito, General Hospital Yogyakarta, Indonesia Dian Paramita Wulandari; Hesti Dyah Palupi; Feri Trihandoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202206

Abstract

Deep neck abscess (DNA) is an infectious condition categorized as anemergency case with high mortality and morbidity. The incidence decreasesover time due to extensive use of antibiotics, operative intervention, andimproved awareness of dental hygiene. Management of DNA must be carriedout appropriately and efficiently to prevent complications that may occur,such as jugular vein thrombosis, pericarditis, and pneumonia. Patients withDNA are often categorized as high-cost patients, because of the long durationof hospitalization, the need for special examinations, and complicatedmanagement. Clinical practice guidelines (CPG) and clinical pathways (CP)are a standard created for management, quality, and cost control. The studyaimed to evaluate the implementation of the CPG and CP in DNA patients atDr. Sardjito General Hospital, Yogyakarta. The study used medical recordsdata of DNA patients from January 2018 to December 2020 who met theinclusion and exclusion criteria. A total of 55 subjects were obtained, withcompliance to complete CPG filling of 98.3% and CP filling of 96.2%. There was100% completion in CPG filling categorized as good compliance, whilst thenumber of good compliances for CP was 92.7%. In conclusion, the diagnosisand management of DNA patients at Dr. Sardjito General Hospital has goodcompliance with CPG and CP available.
Effect of Citrullus lanatus seed oil on xerosis in leprosy patients Puteri Wulandari; Syahril Rahmat Lubis; Deryne Anggia Paramita
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202203

Abstract

Xerosis in leprosy patients may result from defects in sweat gland function.Red watermelon (Citrullus lanatus) seed oil a lot of contains linoleic acid,which can hydrate the skin and reduce trans-epidermal water loss (TEWL).This study aimed to evaluate the effect of C. lanatus seed oil administrationin leprosy patients with xerosis. It was a clinical study with one group pretestposttest control group design involving 30 leprosy patients with xerosis at theDepartment of Dermatology and Venereology, Dr. Pirngadi Medan Hospital, thePolyclinic of Dermatology and Venerology, Universitas Sumatera Utara Hospitaland the Department of Dermatology and Venerology, H. Adam Malik GeneralHospital, Medan, Indonesia. Patients were asked to topically administration of2 mL C. lanatus seed oil to the right and left legs for two times daily for 4 weeks.Specified symptom sum score (SRRC) and skin capacitance (SCap) were thenmeasured before the intervention at the first visit (week 0), week 2, and week 4.A significantly different on SRRC and SCap of the leprosy patients was observedon the 2nd and 4th week after C. lanatus oil administration compared to week 0(p<0.001). No side effects of erythema, blistering, and burning were observed.However, a mild degree itching was observed in 2 (6.7%) patients. Majority ofleprosy patients feel good satisfaction (83.4%), followed by a moderate (13.3%)and a low satisfaction (3.3%). In conclusion, topically administration of redwatermelon (C. lanatus) seed oil can reduce the xerosis degree in leprosypatients as indicated by the decrease of SRRC and the increase of SCap. Theseed oil is well tolerated and gives a good satisfaction on the patients.
Comparison of neutrophil lymphocyte ratio (NLR), mean platelet volume (MPV) and platelet lymphocyte ratio (PLR) in preeclampsia and normotensive pregnancies Dinar Yudistira Firdaus; Assangga Guyansyah; Umiyanti Thenu; Selvia D. Denggo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202204

Abstract

The study aimed to compare the NLR (neutrophil lymphocyte ratio), MPV (meanplatelet volume), and PLR (platelet lymphocyte ratio) values in preeclampsiaand normotensive pregnancies. This was a retrospective case-control studyusing medical records of pregnancies between January 1, – December 31, 2019.A total 31 pregnancies with preeclampsia who met the inclusion and exclusioncriteria were involved in the study. As control, 31 normotensive pregnanciesrecruited by simple random sampling were used. The data were presented asmean ± standard deviation (SD) and analyzed by using SPSS program. Receiveroperating characteristic (ROC) curve were used to determine the optimal cutoff point for predicting preeclampsia. The NLR and MPV values of patients withpreeclampsia were significantly higher compare to normotensive pregnancy(p<0.001). Whereas, the PLR value of both groups was not significantlydifferent (p>0.245). The result of AUC analysis showed that the NLR and MPVhave AUC values of 0.758 (95%CI:0.637-0.878; p=0.000) and 0.903 (95%CI:0.816-0.989; p=0.000), respectively. Further analysis showed that the optimal cut-offpoint for NLR was 4.0 (sensitivity of 64.5% and a specificity of 71.0%) and forMPV was 7.55 (sensitivity of 87.1% and specificity of 80.0%). In conclusion, theNLR and MPV values are significantly higher in preeclampsia. However, theMPV value has a better predictive value than NLR for preeclampsia.
Exercise-based cardiac rehabilitation adaptation protocol during Covid-19 pandemic achieved similar results as compared to non-pandemic usual practice: a single center experience Anggoro Budi Hartopo; Irsad Andi Arso; Ade Meidian Ambari; Bambang Dwiputra; Basuni Radi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202207

Abstract

During the Covid-19 pandemic, exercise-based cardiac rehabilitation (EBCR) faced challenges. Adaptation protocols were implemented to circumvent these challenges. The study aimed to investigate whether the adaptation protocols of EBCR during Covid-19 period influenced the result of cardiac rehabilitation. This was a retrospective cohort study. The subjects were patients who underwent an EBCR program in Dr. Sardjito General Hospital. Yogyakarta, Indonesia. The registry of cardiac rehabilitation was obtained and divided into two periods: non-Covid-19 period and Covid-19 period. During the non-Covid-19 period, 3 EBCR sessions per wk (10-12 total sessions) were performed. During the Covid-19 period, EBCR was reduced to 2 sessions per wk (10-12 total sessions). The functional capacities were evaluated as metabolic equivalents (METs) and exercise test time (min) by treadmill test. A total of 122 subjects completed the EBCR. There were no significant differences in METs and exercise minute achieved between two time periods. Among subjects with different sessions per wk, namely 2, 3, and 4-5 sessions per wk, there were no significant differences in METs (7.01±1.89; 7.23±1.74; and 7.33±2.13, p=0.813) and minutesachieved (6.72±1.94; 6.96±1.96; and 6.81±1.84, p=0.848) in the end sessions. In conclusion, the adaptation of EBCR protocols during the Covid-19 period by reducing the number of sessions per wk has similar results as compared to the usual regular EBCR practice.
Practical tips to adopt active lifestyle for university students during pandemic life: a narrative review Zaenal Muttaqien Sofro; Widya Wasityastuti; Rakhmat Ari Wibowo; Rahmaningsih Mara Sabirin; Siswanto Siswanto; Jajar Setiawan; Denny Agustiningsih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202210

Abstract

The Covid-19 pandemic worsened the physical inactivity pandemic and also increased sedentary behavior across the population, including university students. While physical inactivity and sedentary behavior are detrimental to health and academic performance, there is an urgent need to help university students to adopt an active lifestyle during post-pandemic life. This narrative review discussed current physical activity (PA) and sedentary behavior recommendations, practical tips for adopting an active lifestyle by applying PA doses using the frequency, intensity, time, and type (FITT) principle, and behavioral strategies to adopt and maintain an active lifestyle. Finally, several considerations related to the PA-related musculoskeletal injury and cardiovascular events risks were also discussed with examples from interventions during the pandemic in university settings.
Family-centered rehabilitation in high risk infant; A case report Lulus Hardiyanti; Rizky Kusuma Wardhani; Aditya Rifqi Fauzi; . Gunadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202209

Abstract

Preterm infants are categorized as a high-risk group in neonatology. Theyare physiologically less mature and have limited compensatory responsesto the extrauterine environment compared with term infants. Preterminfants need long-term evaluation, monitoring, and follow-up to optimizeneonatal care and development through an extensive rehabilitationperiod. However, the COVID-19 pandemic restricted patient care andfollow-up in the outpatient hospital setting. This case report discusses ahigh-risk infant treated with family-centered rehabilitation (FCR). Thepatient's rehabilitation issues included delays in gross motor, fine motor,and language development and preventing complications that may arisein a high-risk premature infant. Considering recent occurrences, ourapproach to rehabilitation programs for high-risk infants needs to bereevaluated and revised, focusing on home programs through familycentered treatment. These techniques may aid in delivering rehabilitationtreatments to children with developmental delays during COVID-19.
Maternal determinants of average weekly fetal weight gain in Yogyakarta, Indonesia Eugenius Phyowai Ganap; Pakartian Ayu Sugmana; Riantina Rizky Amalia; Laksmi Ika Hidayati; Aditya Doni Pradana Doni Pradana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 4 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005404202208

Abstract

Average fetal weight gain (AWG) is one of the important parameters usuallyused as an indicator to identify the fetal risk of poor outcomes of intrauterinegrowth restriction (IUGR) or macrosomia. This study aimed to investigate theassociation between AWG and maternal factors such as body weight (BW), bodymass index (BMI), middle-upper arm circumference (MUAC), and economicstatus in Yogyakarta, Indonesia. This community-based cross-sectional studywas conducted in one district in the Yogyakarta Special Province, Indonesia.The study included 50 mother-infant pairs who delivered at term (37-42 weeksof pregnancy). The mother’s BW, height, BMI, and MUAC were recorded usinga case-report form. Questionnaires were also completed to establish therespondents’ economic status. Maternal factors associated with fetal birthweight were determined using univariate and multivariate analyses. Themothers registered in our study mostly had good nutritional status (74.0% hadan optimal MUAC > 23cm). The mean AWG and birth weights were 172.6 ±24.5g/wk and 3.08 ± 0.34kg, respectively. Univariable analysis models wereused to assess the associations between each variable and AWG (with a cut-offvalue of 153.8 g/wk). Our study found no associations between higher MUACand higher AWG (OR=1.03; 95% CI: 0.83-1.27; p=0.77) and energy intakes perday with AWG (OR=1.0; 95% CI: 1.00-1.001; p=0.21). Socioeconomic factors suchas the mother’s educational background also showed no association with AWG(OR=0.38; 95% CI: 0.92-1.57; p=0.18). In conclusion, this finding shows that thereis no association between variables such as MUAC, mother’s age, energy intake,and educational background with the average fetal weight gain achieved.

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