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INDONESIA
Indonesian Journal of Tropical and Infectious Disease
Published by Universitas Airlangga
ISSN : 20851103     EISSN : 23560991     DOI : -
Core Subject : Health, Science,
Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health
This journal is a peer-reviewed journal established to promote the recognition of emerging and reemerging diseases specifically in Indonesia, South East Asia, other tropical countries and around the world, and to improve the understanding of factors involved in disease emergence, prevention, and elimination. The journal is intended for scientists, clinicians, and professionals in infectious diseases and related sciences. We welcome contributions from infectious disease specialists in academia, industry, clinical practice, public health, and pharmacy, as well as from specialists in economics, social sciences and other disciplines.
Arjuna Subject : -
Articles 334 Documents
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Polyvinyl Chloride (PVC)-Glycerol with Chitosan Addition for Antibacterial Blood Bag Application Prihartini Widiyanti; Tarissa Diandra Putri Wibowo; Andhi Baskoro; Siswanto
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 2 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i2.43104

Abstract

Blood bag is a medical device that stokes and transports whole blood or blood components. The material that is often used for blood bag membranes is Polyvinyl Chloride (PVC), however the common problem that is bacterial contamination and that material have not antibacterial characteristic.  Because of this matter, the aim of this reseach are a blood bag that has antibacterial function is needed and meet the ideal standard as bloodbag. Chitosan as a blood bag membrane material fabrication to get the antibacterial effect. Chitosan is chosen as a blood bag material fabrication to get the antibacterial effect. Chitosan has several specific biocompatibility properties, antibacterial, chelation, and biodegradability. This study used various Chitosan concentrations of 1.5%, 2%, 2.5%, and 3%, and Glycerol was added as a plasticizer. The composition of Chitosan: Glycerol is 1:1. Then, the mixture is added to the PVC solution in a ratio of 1:5 then poured into a petri dish. The results showed characterization that the biocomposite PVC-Glycerol with the addition of 3% concentration of chitosan was the best composition, the tensile strength test result of biocomposite is 21.20 MPa, the absence of membrane pores in the morphology of the blood bag, the hemolytic activity is 0.24%, and the inhibition zones of E. coli and S. aureus, respectively 11.66 mm and 12.66 mm in diameter. Based on the characterization results, the biocomposite PVC-Glycerol membrane with the addition of Chitosan has a very high potential as a candidate for blood bag membranes
Measurements and Accuracy of IgM and IgG Anti Phenolic Glycolipid-1 Levels in Blood Serum for Early Detection Mycobacterium leprae by using Enzyme-Linked Immunosorbent Assay (ELISA): A Reality of a Laboratory Salsabilla Putri Kinanti Abdullah; Dinar Adriaty; Iswahyudi; Puput Ade Wahyuningtyas; Laura Navika Yamani; Medhi Denisa Alinda; Ratna Wahyuni; Cita Rosita Sigit Prakoeswa
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 2 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i2.43481

Abstract

Indonesia was the third most recent case of leprosy globally in 2020 with 11,173 people, after India and Brazil. Most of the leprosy manifestations are asymptomatic. This is possibly as subclinical leprosy which individuals without leprosy symptoms but have leprosy specific antibodies high levels, so it has the potential to become a transmission and disability. Therefore, an ELISA test need for early detection in preventing leprosy transmission. This study aims to measure IgM and IgG antibody levels in leprosy patients and assess the accuracy of the measurement results. This research is a cross-sectional study. Five patients' blood samples have analyzed for IgM and IgG anti-PGL-1 antibody levels by ELISA. Accuracy interpretation of this measurement based on the %CV. Antibody levels were classified based on the cut-off <605 u/ml as IgM seronegative or <630 u/ml as IgG seronegative, 605–1000 u/ml as low seropositive IgM or 630-1000 u/ml as low seropositive IgG, and >1000 u/ml as high seropositive IgM and IgG. Among five patients examined, 40% had high seropositive leprosy with anti-PGL-1 IgM and IgG antibody titers>1000 u/ml, and 60% of patients had seronegative leprosy. Accuracy in this ELISA test shows high accuracy with %CV <10% in the conversion of OD to antibody titer levels.  IgM and IgG Anti PGL-1 antibody titers by ELISA as one of the parameters in identifying patients at higher risk of leprosy. A significant portion of patients with high seropositive leprosy with high accuracy.
Diagnostic Test of Blood Eosinophil Level as a Marker of Ascaris lumbricoides Infection Said Munazar Rahmat; Teuku Romi Imansyah Putra; Merina Panggabean; Aman Agustinus Depari; Dhiatama Endalif
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 2 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i2.46603

Abstract

A. lumbricoides infection is one from 17 neglected tropical diseases in Indonesia. But, Infection of A. lumbricoides in Indonesia often undiagnosed. This is because stool examination with Kato-Katz’s method still rarely done. So it needs something alternative examination that more practical and can be routinely carried out. This study was a diagnostic test for blood eosinofil levels in diagnosing A. lumbricoides infection. This research was conducted at a hospital in Medan. This study involved 63 children who had their parents approval. Children stool were examined by Kato-Katz method as a gold standard and blood eosinofil levels was examined as an index in this study. The results showed sensitivity level of eosinofil is 25% and specificity 96,08%, positive predictive value 60%, negative predictive value 84%, positive likelihood ratio 6,38% and negative likelihood ratio 0,78%. The conclusion is elevated blood eosinofil levels cannot be used as an alternative test Kato-Katz in diagnosing Infection of A. lumbricoides.
The Existence of Leptospira interrogans on Rats and The Transmission Potency in Public Areas: School, Traditional Market, and Settlement in Yogyakarta Raden Roro Upiek Ngesti Wibawaning Astuti; Salsabila Rifda Yuangga; Fahrunniam
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 2 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i2.46918

Abstract

Leptospirosis is a zoonotic disease caused by bacterial infection, Leptospira interrogans. Indonesia is known for being an endemic country of this disease and Yogyakarta Special Province has become one of the regions with high cases of Leptospirosis. There was lack of information on the L. interrogans prevalence on rats at the public areas, such as school and traditional market. This research was conducted to determine and predict the potential Leptospirosis transmission in public areas, especially in schools, traditional markets,. and the settlement of Yogyakarta. Wild rats were collected from several public places (elementary schools, traditional markets, and Settlement areas) by using single live traps. The rat's blood was centrifuged to obtain the serum. The serum was tested by using immunochromatography of Leptotek Lateral Flow. The collected rats and shrews were euthanized and then identified for the species and the morphological features. Total of 27 rats (67.5%) and shrews 13 (32.5%) were collected. There were six species of collected rats, namely Rattus argentiventer, Rattus norvegicus, Rattus tanezumi, Rattus tiomanicus, and Bandicota bengalensis, while the collected shrew species was Suncus murinus. The rats and shrews from traditional market were negative with L. interrogans, however the positive results was in elementary schools (14.28%), that were from R. norvegicus and S. murinus, moreover the positive infection also showed in the settlements (57.14%), that were from R. argentiventer, R. norvegicus, and R. tiomanicus. These findings indicated that school and settlement must be a concern for the leptospirosis transmission.

Page 34 of 34 | Total Record : 334

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