Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Biology, Medicine, & Natural Product Chemistry

BIOMEDICH
Website

Published by Universitas Islam Negeri Sunan Kalijaga Yogyakarta

ISSN : - EISSN : - DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for researchers in these fields, and with the aim to set international standards in their methodology.

Arjuna Subject : -

Articles 196 Documents

1 2 3 4 5

The Phytoestrogenic Potential of Yam Bean (Pachyrhizus erosus) on Ovarian and Uterine Tissue Structure of Premenopausal Mice Cicilia Novi Primiani
Biology, Medicine, & Natural Product Chemistry Vol 4, No 1 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

The use of estrogen hormone by public has significantly been improved either as prevention or treatment of disease. Menopausal issues in women are often treated using hormone replacement therapy. In regard to this, yam bean is found to contain genistein and daidzein compounds with a chemical structure that resembles estrogen hormone, therefore yam bean is categorized in the phytoestrogen group. The purpose of this study was to identify the potential of yam bean on ovarian and uterine histology of mice. This research employed a Completely Randomized Design of experimental research approach of one factor namely yam bean in three different dosage treatment: 0.3 g/kg, 0.6 g/kg, and 0.9 g/kg of yam bean for 24 days. The surgery and organ harvesting of ovary and uterus were conducted on Day 25 along with the making of histological preparat using paraffin method and Hematoxylin-eosin (HE) staining. The data was then analyzed descriptively. This research found that there were both secondary and tertiary follicle proliferation as the antrum contains some estrogen level. Meanwhile, the endometrial tissue of the uterus experienced uterine glandular proliferation. To conclude, yam bean was found to be a natural estrogen source.

A Discovery and Characteristics Description of Telosma puberula (Asclepiadoideae) in Mount Gedang Atas and Mount Ijo, Baturagung Mountain Yogyakarta Widodo Widodo
Biology, Medicine, & Natural Product Chemistry Vol 3, No 2 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Population of Telosma puberula in community forest bushes was identified at S.07.48'.44.1"; E.110.31.15.8", 411m, Mount Gedang Atas and S 070 04 '04.1"; E 1100 30 '47.9 ", 415m, Mount Ijo. Telosma puberula was also found in Mount Parangan, Mount Mintorogo, Mount Nglanggeran, and Baturagung Mountains Yogyakarta. The identification was based on herbarium specimens collected by Horsfield in 1802 and 1859 from Java island, Indonesia (K000873052, K000873053). Information about Telosma puberula is very limited. This article describe photographs of morphological characters of the plant’s stems, leaves, flowers, and pollinia.

Substitution and Haplotype Diversity Analysis on The Partial Sequence of The Mitochondrial DNA Cyt b of Indonesian Swamp Buffalo (Bubalus bubalis) Akhmad Sukri; Mohamad Amin; Aris Winaya; Abdul Gofur
Biology, Medicine, & Natural Product Chemistry Vol 3, No 2 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

This research aims to investigate the substitution pattern of nucleotide base and haplotype diversity of Indonesian swamp buffalo (Bubalus bubalis) based on the mitochondrial DNA cyt b partial gene sequence. 17 samples were chosen from 7 different regions with each uniquely represents Indonesian biogeography which comprise Aceh, Riau, Madiun, Blitar, Lombok, South Borneo and Tana Toraja. The result of cyt b gene sequence alignment showed the presence of transition and transversion substitutions and the absence of insertion and deletion. The amount of transitions was found to be higher than that of transversions and the amount of substitution in pyrimidine was also higher than that in purine. The highest amount of transitions happened in base TàC which is a silent substitution. The result of median joining network analysis showed that Indonesian haplotype Bubalus bubalis could be classified into 16 haplotypes which form different haplogroups unique to their geographical region. The result of median joining network analysis also indicated that the genetic relationships of swamp buffaloes (Bubalus bubalis) in Indonesia are highly influenced by their geographical locations.

The Effect of Water-Soluble Stem Extract “Kayu Kuning“ (Arcangelisia flava L.Merr) On The Growth Inhibition of Candida albicans ATCC 10231 and Trichophyton mentagrophytes IN VITRO Rini Setyowati; Sudarsono Sudarsono; Setyowati E P
Biology, Medicine, & Natural Product Chemistry Vol 3, No 1 (2014)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

“Kayu kuning” (Arcangelisia flava L.Merr) was used when someone has a skin problem caused by Candida albicans and Trichophyton mentagrophytes. Scientific based medicine on this traditional knowledge was necessary be done. Stem powderwas extracted by distilled water.The extract was then evaporated. Qualitative and quantitative analysis of the active substance e.g., Berberin chloride by Thin Layer Chromatography (TLC) The antifungal activity againts Candida albicans and Trichophyton mentagrophyteswere tested by using agar diffusion and microdilution methods. The absorbance from microdilution were analized by One way ANOVA. The conclusion showed that the extract contained 1.55±0.12% w/walkaloid calculated as Berberine chloride. The inhibition zone for Candida albicans and Trichophyton mentagrophytes were 16.65±4.52 and 6.55±0.05 mm respectively. The MIC vallue for both fungi was 10 mg/mL.The MBC value for Candida albicans was 40 mg/mL and for Trichophyton mentagrophytes was 50 mg/mL. From the analysis with one-way ANOVA, shows that there are significant differences between the positive control group and the test solution with the negative control group with p=0.020 for Candida albicans and p=0.028 for Trichophyton mentagrophytes (p<0.050). Post hoc Tukey analysis results showed that both inter-group and between the concentration of the test solution to the control group did not differ significantly positive because the value of p>0.050.

Effect of Lunasia amara Blanco on Sperm Number, Sperm Motility, and Testicular Histology of Male Rats Muhammad Ja’far Luthfi
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Sanrego (Lunasia amara), has been used in the folk medicine to increase and/or to treat male fertility. However there is no scientific evidence to confirm the positive effect of the plant on an improvement of male fertility. The objective of this research was to study the effects of the plant (on adult Sprague-Dawley male rats) at the doses of 30 mg/kg, 60 mg/kg, and 90 mg/kg on the sperm count, motility, and testicular histology. Administration were given by force-feeding between 10.00 am and 12.00 pm daily for a period of 42 days followed by sperm quality analysis and testicular histology evaluation. The sperm analysis showed that the sanrego increased the sperm count and sperm motility. The testicular histology also revealed positive effect of the plant on spermatogenesis. Overall the present study showed the sanrego is potential plant to increase male fertility.

Medicinal Plants: A Prospect in Developing Male Fertility Enhancing Agent Muhammad Ja’far Luthfi; Mahanem Mat Noor; Jalifah Latip
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Medicinal plants have been a revolutionary breakthrough in the treatment of male sexual dysfunction. Traditional medicine based on a holistic philosophy is quite different with the practice of “western” medicine. Phytochemical substances focus their mechanisms of healing to the root of cause, i.e. the inability of controlling the proper function of the whole body system. Hence, medicinal plants manage sexual dysfunction and male fertility in the frame of sexual dysfunction as a whole entity. Some previous researches prove that the use of medicinal plants have a good impact in the treatment of a variety of male sexual problems. This paper will discuss several important aspects of aphrodisiac plants and preliminary study regarding them in Indonesia. Difficulties inherent to activity guided isolation and the specific requirements of bioassays are also discussed.

Krokot (Portulaca oleracea L) As a Natural Sensitizer for TiO2 Dye-sensitized Solar Cells: The Effect of Temperature Extract Reyza Anni Mufidah; Khamidinal Khamidinal; Endaruji Sedyadi; Didik Krisdiyanto
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

The solar cell is formed by a sandwich structure, in which two electrodes flank the primary electrolyte that is containing redox I-/based on PEG (Polyethylene Glycol). The working-electrode which is TiO2 layer on an ITO glass substrate is sensitized with krokot dye as the electron donor. The counter electrode is a layer of carbon. The fabrication cell is immersed with the krokot dye with 40°C, 50°C, 60°C extract temperature. The result of the UV-Vis shows that the absorption of wave-length from dye extract of krokot is located in the visible region with the absorbance peak in 420,5 nm and 665,5 nm which are the peak of chlorophyll. For the UV-Vis solid system, there are the highest band gap in 50°C extract temperature that make the capability of absorption toward UV spectrum is large. Furthermore, in the functional group analysed by FT-IR, there are shiften-carbonil and hydroxyl group after they are sensitized. From the current and voltage test with I-V meter keithley 2400 is resulted that on the 50°C extract temperature produces the highest efficiency of reaches which is 2.63 x 10-3 %.

Tapak Liman (Elephantopus scaber L) As Immunostimulant and Its Effect on Lymphocyte Differentiation in Mice BALB/C Marmi Kelik
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Tapak liman (Elephantopus scaber L) is one of the plants that have medicinal properties and has been used for maintenance and improvement of health and disease treatment. The purpose of this study was to determine the effect of extracts of Tapak Liman (Elephantopus scaber L) as immunostimulant to the development of lymphocytes in mice BALB / C. The procedure of this study was to test aqueous extracts in vivo with various treatments (control, treatment of 0.5 g / kg, 1.0 g/ kg, 2.0 g / kg) in healthy mice BALB / C for 2 weeks. After the treatment carried out analysis of the percentage and number of cells that express CD4+, CD8+ and CD4+ CD8 + in thymus organ, using flowcytometry. Analysis of data using one-way ANOVA followed Tukey's test with SPSS. From the analysis showed that the extract of Tapak liman at various doses showed no significant effect on the percentage expression of CD4 + CD8 + and CD4 + CD8 + in thymus organs. While the analysis of the number of cells, extracts of Tapak liman show its effect on the number of cells that express CD4+, CD8 + and CD4 + CD8 + in thymus organs. Concentration of 1.0g / kg of mice showed a good effect on the increase in T helper cells (CD4 +), cytotoxic T cells (CD8 +) and Prothymosit cells (CD4 + CD8 +).

Antioxidant Potential of Black, Green and Oolong Tea Methanol Extracts Wahyu Widowati; Tati Herlina; Hana Ratnawati; Gabriella Constantia; I Dewa Gde Sathya Deva; Maesaroh Maesaroh
Biology, Medicine, & Natural Product Chemistry Vol 4, No 2 (2015)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Degenerative diseasesandchronicdiseasesare oftencausedbyoxidativestress. Oxidative stress caused by free radicals. Antixodant as inhibitor are needed to prevent it which is one of antioxidant sources is tea. Tea processinggenerally produce various kinds of teas such as black, green and oolong tea. Tea processing affect thecontent ofphenolic compounds. The aim of the research is to evaluate phytochemical content, totalphenolic content of blacktea, green tea andoolongtea extracts using catechin, quercetin, kaempferol, myricetin as standard, and to evaluate the antioxidative potency of black tea, green tea and oolong tea extracts compared to catechin, quercetin, kaempferol, myricetin. Phytochemical assay using modified Farnsworth method, the antioxidant activity were measured by by its 1,1-diphenyl-2-picryl-hydrazyl (DPPH) scavenging activity. Green tea extract contained highest phenolic and flavonoid. The highest antioxidant activity was green tea extract with IC50=0,487μg/mL. Green tea extract content phenol and flavonoid are higher compared to the other extracts, green tea extract has the highest antioxidant activity.

Comparative Anatomy and Histology of Black Pomfret (Formio niger) and Nile tilapia (Oreochromis niloticus) Kidney Nurul Safitri Apriliani; Muhammad Jafar Luthfi
Biology, Medicine, & Natural Product Chemistry Vol 6, No 1 (2017)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Black pomfret and nile tilapia are belonging to order Perciformes. Both fish are live in different habitat. Black pomfret is marine water whereas nile tilapia is in freshwater. The purpose of the study was to determine anatomy and histology of the kidneys structures in both fishes. Histological preparations were done using paraffin method, with Hematoxylin-Eosin (HE) staining. The results, showed that Black pomfret and nile tilapia have y-shape kidney. Nile tilapia has darker red colour and softer texture than black pomfret kidney. Histologically, black pomfret and nile tilapia kidneys have a distal tubule, proximal tubule, glomerulus and lymphoid tissue. Glomerular diameter of nile tilapia (69,22 µm) was larger than pomfret (61,25 µm). It can be concluded that differences between anatomical and histological structure of kidney are affected by habitat differences.

Page 2 of 20 | Total Record : 196

1 2 3 4 5

Filter by Year

2014 2023

Filter By Issues

All Issue Vol 12, No 2 (2023) Vol 12, No 1 (2023) Vol 11, No 2 (2022) Vol 11, No 1 (2022) Vol 10, No 2 (2021) Vol 10, No 1 (2021) Vol 9, No 2 (2020) Vol 9, No 1 (2020) Vol 8, No 2 (2019) Vol 8, No 1 (2019) Vol 7, No 2 (2018) Vol 7, No 1 (2018) Vol 6, No 2 (2017) Vol 6, No 1 (2017) Vol 5, No 2 (2016) Vol 5, No 1 (2016) Vol 4, No 2 (2015) Vol 4, No 1 (2015) Vol 3, No 2 (2014) Vol 3, No 1 (2014) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kab. sleman, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kab. sleman,

Daerah istimewa yogyakarta

INDONESIA