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Majalah Obat Tradisional
Published by Universitas Gadjah Mada
ISSN : 14105918     EISSN : 24069086     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, Daerah Istimewa Yogyakarta, and we dedicate our journal to researches and development in traditional medicine. The journal receives papers on research laboratory, field research, and case studies of traditional medicine and its constituent, covering research topics including raw materials, cultivation, phytochemical, pharmacological effects and toxicology, formulation, and biotechnology.
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Articles 6 Documents
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Search results for , issue "Vol 17, No 1 (2012)" : 6 Documents clear
PENGARUH LAMA PENYIMPANAN TERHADAP STABILITAS FISIK DAN KIMIA LOTION PENUMBUH RAMBUT EKSTRAK BIJI KEMIRI (Aleurites moluccana L. Willd.) Mufrod, Mufrod; Prasojo, Anas Putro Senu; Mulyani, Sri
Majalah Obat Tradisional Vol 17, No 1 (2012)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (687.12 KB) | DOI: 10.14499/mot-TradMedJ17iss1pp1-7

Abstract

Ekstrak etanolik 70% biji kemiri dengan konsentrasi 5% dilaporkan memiliki aktivitas menumbuhkan rambut. Penelitian bertujuan untuk mengetahui pengaruh lama penyimpanan terhadap stabilitas fisik dan kandungan flavonoid lotion penumbuh rambut ekstrak biji kemiri sehingga diperoleh suatu sediaan yang acceptable. Lotion dibuat dengan variasi konsentrasi xanthan gum 0,5% ; 1 % ; 1,5%. Pengukuran flavonoid dilakukan dengan metode densitometri . Hasil pengamatan stabilitas fisik yaitu daya lekat, viskositas, dan kadar flavonoid dianalisis secara  statistik. Hasil orientasi formula, lotion dengan konsentrasi xanthan gum 1% adalah yang terbaik dengan daya lekat kurang dari 1 detik, viskositas tiap minggunya naik, dan tidak terjadi pemisahan. Tipe emulsi yang dihasilkan adalah o/w. Hasil densitometri menunjukkan bahwa terjadi penurunan kadar relatif flavonoid antara sebelum dan setelah penyimpanan namun berbeda tidak signifikan (α = 0,158).
PENGARUH MINYAK ATSIRI DAN EKSTRAK ETANOLIK BEBAS MINYAK ATSIRI DARI RIMPANG JAHE MERAH (Zingiber officinale Rosc. klon merah) TERHADAP EFEK APRODISIAKA PADA TIKUS JANTAN Pramono, Suwijiyo; Nurlaila, Nurlaila; Anandita, Dipta Wana
Majalah Obat Tradisional Vol 17, No 1 (2012)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (723.229 KB) | DOI: 10.14499/mot-TradMedJ17iss1pp8-14

Abstract

Gangguan reproduksi kini banyak dialami terutama pria akibat berbagai faktor. Jahe merah sering digunakan untuk mengatasi gangguan seksual pria. Oleoresin yang terdapat di dalam jahe merah dilaporkan memiliki efek sebagai aprodisiaka. Penelitian ini bertujuan untuk membandingkan efek minyak atsiri dan ekstrak etanolik bebas minyak atsiri sebagai aprodisiaka. Minyak atsiri jahe merah diambil dengan cara destilasi sementara simplisia bebas minyak atsiri diekstraksi dengan etanol 70%. Tikus dibagi menjadi 5 kelompok yaitu kelompok yang dipejani suspensi ekstrak etanolik jahe merah (140 mg/kg BB), emulsi minyak atsiri (15 μl/kg BB), kontrol positif suspensi ekstrak pasak bumi (500 mg/kg BB), kontrol positif suspensi serbuk jahe merah (2,5 g/kg BB), dan kontrol negatif suspensi CMC Na 1%. Pemejanan dilakukan secara oral setiap hari selama 32 hari. Parameter yang diamati adalah frekuensi introduction, climbing, dan coitus. Hasil penelitian menunjukkan suspensi minyak atsiri mampu meningkatkan libido meskipun tidak sebesar suspensi ekstrak pasak bumi, sementara suspensi ekstrak etanol jahe merah dan kontrol positif suspensi serbuk jahe merah tidak mampu meningkatkan libido dan aktivitas seksual dibanding kontrol negatif.
FORMULASI HARD CANDY LOZENGES EKSTRAK DAUN LEGUNDI (Vitex trifolia L.) Sulaiman, T. Nanda Saifullah; Murti, Yosi Bayu; Alkarim, Mahfud
Majalah Obat Tradisional Vol 17, No 1 (2012)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (638.144 KB) | DOI: 10.14499/mot-TradMedJ17iss1pp15-21

Abstract

Tujuan penelitian ini untuk mengetahui pengaruh variasi kadar gula (sukrosa dan glukosa) terhadap sifat fisik dan rasa, serta mengetahui tingkat kesukaan konsumen pada hard candylozenges ekstrak daun legundi.Hard candy lozenges diproduksi menggunakan metode peleburan dengan membuat tiga formula kombinasi sukrosa dan glukosa yaitu FI (70%:30%), FII (50%:50%), dan FIII (30%:70%). Hard candy lozenges diuji sifat fisik meliputi: keseragaman bobot, kekerasan, uji kadar air, waktu larut dan KLT-densitometri serta uji tanggap rasa menggunakan kuesioner dengan penilaian secara scoring oleh reponden. Hasil pengujian dianalisa menggunakan SPSS 11.0 for windows dengan taraf signifikansi (α) = 0,05. Hasil penelitian menunjukkan bahwa adanya variasi kadar sukrosa dan glukosa mempengaruhi sifat fisik hard candy lozenges ekstrak daun legundi yaitu meningkatkan kekerasan, dan memperlama waktu larut (p < 0,05) tetapi tidak mempengaruhi kadar air tablet (p > 0,05). Semakin banyak sukrosa yang digunakan maka tablet menjadi semakin keras dan waktu larut menjadi semakin lama. Berdasarkan hasil uji tanggap rasa hard candy lozenges ekstrak daun legundi secara subjektif, Formula III paling disukai oleh responden dengan perbandingan sukrosa dan glukosa 30%:70%.
FORMULASI HARD CANDY LOZENGES EKSTRAK DAUN LEGUNDI (Vitex trifolia L.) Mahfud Alkarim; Yosi Bayu Murti; T. Nanda Saifullah Sulaiman
Majalah Obat Tradisional Vol 17, No 1 (2012)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (638.144 KB) | DOI: 10.22146/tradmedj.8000

Abstract

The purpose of this study is to determine the effect of sugar level variations (sucrose and glucose) to the physical properties and flavor, as well as to determine the level of consumer preferences on hard candy lozenges of Legundi leaf extract. Hard candy lozenges are produced using the fusion method to create three formulas contain combination of sucrose and glucose, which is FI (70%: 30%), FII (50%: 50%), and FIII (30%: 70%). Hard candy lozenges were tested the physical properties include: uniformity of weight, hardness, moisture content test, a soluble and TLC-densitometry and responsive taste test using a questionnaire with scoring assessment by respondents. The test results were analyzed using SPSS 11.0 for windows with a significance level (α) = 0.05. The results showed that the variation of sucrose and glucose levels affect the physical properties of hard candy lozenges of Legundi leaf extract that increases the hardness level, and increase the time to dissolve (p <0.05) but did not affect the water content of the tablet (p> 0.05). The more sucrose is used it increase the hardness of the tablets and dissolve into the longer time. Based on the perceptive sense test results subjectively of hard candy lozenges of Legundi leaf extract, Formula III is the most favored by respondents with sucrose and glucose ratio of 30%: 70%.
PENGARUH LAMA PENYIMPANAN TERHADAP STABILITAS FISIK DAN KIMIA LOTION PENUMBUH RAMBUT EKSTRAK BIJI KEMIRI (Aleurites moluccana L. Willd.) Anas Putro Senu Prasojo; Sri Mulyani; Mufrod Mufrod
Majalah Obat Tradisional Vol 17, No 1 (2012)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (687.12 KB) | DOI: 10.22146/tradmedj.7998

Abstract

Etanolic extract 70% of candlenut which has 5% concentration have been reported to have hair restoring activity. This study aims to investigate the effect of length storage on physical stability and flavonoid content of hair restoring lotion candlenut extract so that produce an acceptable form. Lotion were made in variation of xanthan gum concentration 0.5%; 1%; 1.5%. Flavonoid content were measured by densitometry. Observation result of physical stability such as latched power, viscosity test, and flavonoid content were statistically analyzed. Result of formula orientation showed that lotion which has 1% concentration of xanthan gum was the best which has latched power less than 1 second, viscosity increased weekly, and segregation was not occur. Type of emulsion result was o/w. Densitometry result showed that there were decrease of relative flavonoid ontent before and after storage, but it was not significant (α = 0.58).
PENGARUH MINYAK ATSIRI DAN EKSTRAK ETANOLIK BEBAS MINYAK ATSIRI DARI RIMPANG JAHE MERAH (Zingiber officinale Rosc. klon merah) TERHADAP EFEK APRODISIAKA PADA TIKUS JANTAN Dipta Wana Anandita; Nurlaila Nurlaila; Suwijiyo Pramono
Majalah Obat Tradisional Vol 17, No 1 (2012)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (723.229 KB) | DOI: 10.22146/tradmedj.7999

Abstract

Nowadays, many young men experience sexual disfunction due to many factors. Red ginger is  traditionally used to solve problems related to sexual disfunction. Oleoresin compound of red ginger has been reported to function as aphrodisiac. This research aims to compare aphrodisiac effect of  essential oil and essential oil free extract  in male rats. Red ginger essential oil was obtained by  destilation  while the red ginger free of essential oil was extracted using ethanol 70%. Rats were divided into five groups, administered by : etanolic extract suspension (140 mg/kg BM), essential oil emultion (15 μl/kg BM), pasak bumi extract suspension as positive control (500mg/kg BM), red ginger powder suspension as positive control (2,5 g/kg BM), and CMC Na 1% suspension as negative control. All rats were treated orally for 32 days. Parameters measured were introduction, climbing, and coitus frequency. The result showed that essential oil increased libido but its activity was lower  than pasak bumi.  Etanolic extract of red ginger and red ginger powder did not increase libido and sexual activity as compared with negative control.

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