Garuda - Garba Rujukan Digital

All

IDJP (Indonesian Journal of Pharmaceutics)

idjp
Website

Published by Universitas Padjadjaran

ISSN : - EISSN : 25978748 DOI : -

Core Subject :

The Indonesian Journal of Pharmaceutics (IdJP) is an established international journal for pharmaceutical scientists concerned in all fields of pharmaceutical sciences, including pharmaceutical preformulation, formulation, manufacturing technologies, drug delivery systems, biopharmaceutics, and pharmacokinetics for drugs, vaccines and biologicals. IdJP also includes pharmaceutical engineering and industrial pharmacy topics.

Arjuna Subject : -

Articles 5 Documents

Search results for , issue "Vol 1, Issue 2, May - August 2019" : 5 Documents clear

Formulation of Peel-off Gel Mask containing Mung Bean (Vigna radiata (L.) Wilczek) Extract Patihul Husni; Ella Masliana Dewi
Indonesian Journal of Pharmaceutics Vol 1, Issue 2, May - August 2019
Publisher : Universitas Padjadjaran (Unpad)

Mung bean (Vigna radiata (L.) Wilczek) is one of the plants that rich in antioxidant compound. Antioxidant is a compound that can inhibit the skin aging process because of photoaging. The aim of this study was to formulate peel-off gel mask containing mung bean (Vigna Radiata (L.) Wilczek) extract using polyvinyl alcohol (PVA) as a base of mask and Hidroxy Prophyl Methyl Cellulose (HPMC) as a viscosity increasing agent and to determine the antioxidant activity of the peel-off gel mask. Antioxidant activity was tested using DPPH (1,1-diphenyl-2-pycrilhidrazil) assay. Mung bean was extracted by maceration method using ethanol 96%. The concentration of mung bean extract in the peel-off mask gel was 4% and various concentration of PVA were 5% (F1), 7.5% (F2), 10%(F3). The evaluations were organoleptic, pH, viscosity, drying and film forming, and gel spreadness. The study result showed that the organoleptic of the gel was brownish yellow with pH approximately 6, 196-513 cps in viscosity, 0.0646-0.0730 cm/g in gel spreadness and 27.6-54.5 second in drying and film forming. F3 containing mung bean extract 4%, PVA 10%, HPMC 2%, propylene glycol 15%, potassium sorbate 0,2%, olive oil 0,5%, alpha tocopherol 0,05 and aquadest ad 100% was the best formula with IC50 value was 85,2793 ppm and significantly different than F1 and F2 (p < 0.05).Keywords: peel-off gel mask, mung bean extract, Vigna radiata (L.) Wilczek, antioxidant

Fabrication of Native and Enzymatically Modified Durian Seed (Durio zibethinus Murr.) Starch Susi Afrianti Rahayu; Nasrul Wathoni; Sriwidodo Sriwidodo; Lisa Sophianingsih
Indonesian Journal of Pharmaceutics Vol 1, Issue 2, May - August 2019
Publisher : Universitas Padjadjaran (Unpad)

Durian seed (Durio zibethinus Murr.) has a high starch content (46.2%) and thus can be used as a new source of starch for the raw materials of pharmaceutical and food industries. In this study, we fabricated native and enzymatically modified durian seed starch using a rough enzyme extract from Saccharomycopsis fibuligera. Wet grinding method was used for starch production. Physicochemical characterization of the starches was investigated by organoleptic, acidity-basicity, loss on drying, flow capability, compressibility, ash content and microbial limit. In addition, viscoamylograph had been done to clarify the viscosity properties of the starches. The result of starch production showed that the durian seed had a starch yield of 17.68%. Physicochemical characterization of the starch showed that the results of quality testing had fulfilled the Indonesian Pharmacopoeia 4th edition standards requirements, such as description, identification, acidity-basicity, loss on drying, ash content and microbial limit. In addition, viscoamylograph study showed that the enzymatically modified durian seed starch had a higher viscosity than the native durian seed starch. Interestingly, modification of the durian seed starch using a rough enzyme extract improved its flow capability and compressibility. These results suggest that the modified durian seed starch experienced an increase in viscosity, compressibility and flow capability compared to native durian starch. Keywords: durian, seed, starch, enzymatic modification

Isolation and Characterization of Microcrystalline Cellulose Derived from Plants as Excipient in Tablet : A Review Nagina Gulab Belali; Anis Yohana Chaerunisaa; Taofik Rusdiana
Indonesian Journal of Pharmaceutics Vol 1, Issue 2, May - August 2019
Publisher : Universitas Padjadjaran (Unpad)

Microcrystalline cellulose (MCC) is a versatile and frequently used material in different industries such as pharmaceuticals production, medical, cosmetics, and food industry. Its qualities of being inert, economic, compatibility, compatibility, non-toxicity, biodegradability, good mechanical properties, high surface area, variety and availability of different grades and biocompatibility has made it very popular. Many research has been done on MCC to isolate it from different plant sources that are economical and eco-friendly. MCC is extracted from α cellulose that is abundant in nature as most of MCC is produced from wood. However, new eco-friendly sources with changes in methods of isolation have been applied for the production of MCC. In this review MCC isolated from different plant-based resources, extraction process parameters, the origin of raw material and its influence on critical material attributes of MCC has been outlined and discussed thoroughly. Since these critical material attributes have a significant effect on tablet making process parameters (compressibility, compatibility and etc) and its post-compression characters.Keywords: Microcrystalline cellulose, isolation, characterization, raw material, tablet

Antioxidant Activities of Muntingia calabura, Syzygium cumini, Ocimum basilicum, and Eleutherine bulbosa using DPPH Method Ani Haerani; Anis Yohana Chaerunisa; Anas Subarnas
Indonesian Journal of Pharmaceutics Vol 1, Issue 2, May - August 2019
Publisher : Universitas Padjadjaran (Unpad)

Antioxidants are substances that can provide endogenous protection and exogenous oxidative stress by capturing free radicals. Many plants are efficacious as antioxidants, namely plants that contain polyphenols, especially flavonoids, so many are formulated as natural antioxidants. Plants such as Muntingia calabura, Syzygium cumini, Ocimum basilicum, and Eleutherine bulbosa contain polyphenol compounds, especially flavonoids which are efficacious as natural antioxidants. This research aimed to study antioxidant activity derived from some potential plants using the DPPH method by calculating the IC50 value of each plant extract. This research method starts from the determination process to prove the validity of the plants used, the extraction process using the maceration method with 70% ethanol solvent, then the antioxidant activity of extracts from each plant was carried out using the DPPH method. This research starts from the determination process to ensure the correctness of the plants used, then the extraction process is carried out using the maceration method with 70% ethanol solvent. After that the antioxidant activity was determined from the four plants using the DPPH method to see the strongest IC50 value among the four plants. IC50 is the concentration of the sample to inhibit 50% of free radicals. The results of IC50 values from ethanol extract of M. calabura leaves, Syzygium cumini leaves, Ocimum basilicum leaves and Eleutherine bulbosa bulbs, were 18.72; 63,84; 141.59 and 173.15 ppm. Ethanol extract of M. Calabura has a smaller IC50 value of 18.72 ppm which has a very strong and most powerful antioxidant from the ethanol extract of Syzygium cumini, Ocimum basilicum and Eleutherine bulbosa. Keywords : Antioxidant, Muntingia calabura, Syzygium cumini, Ocimum basilicum, Eleutherine bulbosa, DPPH Method

The Effect of Citronella Oil Concentration (Cymbopogon nardus (L. ) Rendle) on the Quality of Shampoo and Antifungal Activity of Candida albicans Lidya Ameliana; Alik Almawadah; Lestyo Wulandari
Indonesian Journal of Pharmaceutics Vol 1, Issue 2, May - August 2019
Publisher : Universitas Padjadjaran (Unpad)

Citronella oil (Cymbopogon nardus (L.) Rendle) was formulated into shampoo preparations to overcome dandruff. Dandruff is a condition which exfoliation of the excess horny layer on the scalp and forms fine scales caused by fungal infections of Candida albicans. The purpose of this study was to determine the antifungal activity and quality of the citronella oil shampoo. Citronella oil was taken using a steam distillation method. The oil produced has good quality because it meet the range of organoleptic requirements, which were the refractive index 1.483, density 0.890g/mL and citronellal content 41.720%. MIC (Minimum Inhibition Concentration) to find out the lowest concentration of shampoo which can still inhibit the growth of Candida albicans was 2%. Citronella oil then formulated into shampoo with F1 (4%) F2 (6%) and F3 (8%) oil concentrations. The results of the quality of shampoo evaluation showed that all formulations met the requirements of pH, viscosity, and foam height. In testing the antifungal activity of shampoo was known that the greater the concentration of oil in the shampoo, the greater the antifungal activity in the shampoo.Keywords: Citronella oil, shampoo, antifungal activity

Page 1 of 1 | Total Record : 5

Filter by Year

2019 2019

Filter By Issues

All Issue Vol 4, Issue 3, Sep - November, 2022 Vol 4, Issue 2, May - August, 2022 Vol 4, Issue 1, Jan - April 2022 Vol 3, Issue 3, Sept - Dec 2021 Vol 3, Issue 2, May - August, 2021 Vol 3, Issue 1, Jan - April 2021 Vol 2, Issue 3, Sept - Dec 2020 Vol 2, Issue 2, May - August, 2020 Vol 2, Issue 1, Jan - April 2020 Vol 1, Issue 3, Sept - Dec 2019 Vol 1, Issue 2, May - August 2019 Vol 1, Issue 1, Jan - April 2019 More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota bandung,

Jawa barat

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota bandung, Jawa barat INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota bandung,

Jawa barat

INDONESIA