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INDONESIA
Jurnal Ilmiah Kedokteran Wijaya Kusuma
Published by Universitas Wijaya Kusuma Surabaya
ISSN : 19782071     EISSN : 25805967     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health
Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.
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Articles 340 Documents
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KADAR GLIKOGEN HATI SETELAH LATIHAN AEROBIK DAN ANAEROBIK Hadi, Santika Rentika
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2013): Edisi Mei 2013
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Penelitian ini mempelajari pengaruh latihan aerobik dan latihan anaerobik  terhadap glikogen hati. Penelitian ini menggunakan “eksperimen laboratorik” dengan rancangan penelitian “Randomised Post Test Only Control Group Design”. Sebagai sampel adalah tikus putih jenis wistar sejumlah 30 ekor. Sampel dibagi dalam 3 kelompok dengan cara random masing-masing kelompok 10 ekor. Kelompok eksperimen 1 diberi perlakukan latihan aerobik dengan renang secara terus menerus selama 13 menit, kelompok eksperimen 2 diberi perlakuan latihan anaerobik berupa renang secara intermiten dengan 4 set dan rasio kerja : istirahat = 1:3, sedangkan kelompok kontrol tidak diberi perlakuan. Latihan dilakukan selama 8 minggu, dengan frekwensi latihan 3 kali per minggu. Glikogen hati diperiksa secara histologis dengan menghitung jumlah sel hati yang mempunyai kandungan glikogen dengan masing-masing skornya. Data dianalisis dengan statistik deskriptif, analisis varian pada taraf signifikansi 5 %, disimpulkan : (1) Latihan aerobik  dalam penelitian ini tidak meningkatkan glikogen hati (2) Latihan anaerobik  dalam penelitian ini tidak meningkatkan glikogen hati (3) Pengaruh latihan aerobik dan latihan anaerobik terhadap glikogen hati dalam penelitian ini tidak berbeda secara bermakna (p > 0,05).
ANTHRAX in INDONESIA Rahayu, Asih
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Anthrax is a zoonosis disease caused by Bacillus anthracis bacteria. This bacteria is able to produce an endospora that lasts for decades inside the soil and thus becomes an infection source (endemic areas), causing difficulties to eradicate this disease in Indonesia. This disease mainly infects cattle such as cows, goats, horses, and pigs in some cases. It can also infect humans through three ways which is per cutaneous, per oral, and per inhalation. The clinical manifestations in humans are malignant pustule, hematemesis, pneumonia hemorrhagic or meningitis. The success of eradicating anthrax from humans fully depends on the eradication of this disease from the animals.
THE CHALLENGES OF DIAGNOSTIC AND MANAGEMENT OF ACUTE HEART FAILURE FROM HEMODYNAMIC SUBSET TO APPROPRIATE TREATMENT Sumantra, I Gede
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 2 (2014): edisi Oktober 2014
Publisher : Universitas Wijaya Kusuma Surabaya

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Acute heart failure (AHF) is a common and growing medical problem associated with major morbidity and mortality. Despite the high prevalence of this condition and its associated major morbidity and mortality, diagnosis can be difficult, and optimal treatment remains poorly defined. Identification of the acute triggers for the decompensation as well as characterization of cardiac filling pressures and output is central to management. Evaluation of patients with Heart Failure (HF) is critical for the appropriate selection and monitoring of therapy as well as for the prevention of recurrent hospitalizations.Diagnostic and management AHF is a challenge because of the heterogeneity of the patient population, the existence of a universal definition of understanding, not understanding the pathophysiology, and the lack of bases guideline Evidence-based medicine
EXERCISE STRESS TESTING : WHEN, HOW, AND WHAT IT MEANS? Waskito, Budi Arief
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Exercise stress testing (EST) is a sensitive and informative examination of the cardiovascular response to exercise. Exercise is a common physiological stress used to elicit cardiovascular abnormalities not present at rest and to determine the adequacy of cardiac function. The electrocardiogram is the most common parameter used to evaluate the ischemic response during exercise. Exercise electrocardiography is one of the most frequent noninvasive modalities used to determine the likelihood and extent of coronary artery disease. The test is also used to estimate prognosis, to determine functional capacity, and to evaluate the effects of therapy. The indications, contraindications, protocol, when to terminate, interpretation of the result, and spesific clinical applications will be reviewed in this paper.
THE EFFECTS OF CORN FLOUR WITH TEMPEH FLOUR SUPPLEMENTATION FEEDING IN DIABETES MELLITUS WISTAR RATS TOWARD BLOOD GLUCOSE LEVEL Asmarani, Fatifa; Wirjatmadi, Bambang; Adriani, Merryana
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Background: Diabetes mellitus (DM) is metabolic disorder syndrome characterized by hyperglycemia due to deficiency of insulin secretion. Patients of diabetic patients increases each year, so it needs proper handling. Corn flour is a source of carbohydrates with a low glycemic index to help reduce the rise in blood sugar levels. In addition, supplementation with tempeh flour containing isoflavones act to protect cells from free radical thereby inhibiting damage cells. Fiber in tempeh affect blood glucose levels because it slows the absorption of glucose.Objective: To determine the effect supplementation of corn flour with tempeh flour on blood sugar levels in diabetes mellitus Wistar rats.Methods: The study was true experimental design with Pre-posttest control group design, samples were 20 male Wistar rats aged 2-3 months were then divided into 4 groups (T0, T1, T2, T3.) T0 was injected with alloxan as 30 mg / 150 grams of BB rats are subsequently treated with standard diet; T1 was dministered by standard diet 50% + 50% corn flour; T2 was administered by standard diet 50% + 30% + corn flour tempeh flour 20%; and T3 was administered by standard diet of corn flour 50% + 15% + 35% tempeh flour for 2 weeks. Blood glucose levels were measured with a glucose kit (GOD FS). Research data were analyzed by One Way ANOVA followed by Tukeys Post Hoc test p-value <0.05.Results: There were significant differences on blood sugar levels in all groups (p = 0.000): control group (only dietary standards), T1 (administered by standard diet 50% + corn flour 50%), T2 (administered by a standard diet 50% + cornstarch 30% tempeh flour + 20%) and T3 (administered by standard diet of corn flour 50% + 15% + 35% tempeh flour).Conclusion: corn flour with tempeh flour supplementation effect on decresing of blood sugar levels.
PROFILE OF TETANUS IN CHILDREN AT PROF.KANDOU HOSPITAL 2002-2008 Sanjaya, Ayling; Rampengan, Novie Homenta; Rampengan, Tommy Homenta
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2013): Edisi Mei 2013
Publisher : Universitas Wijaya Kusuma Surabaya

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Backgrounds. Tetanus or lockjaw is an acute disease dwelling central nervous system caused by tetanoplasmin toxin produced by Clostridium tetani. Muscle spasm without consciousness disorder is distinguishing symptoms of tetanus. Tetanus in children remains as a health problem in developing countries including Indonesia.Objectives.  To study the profile of tetanus in children.Methods. Retrospective review of children diagnosed as tetanus at Prof. Dr. R.D.Kandou Hospital from 2002 to 2008. The datas were analyzed descriptively.Results.  There were 17 children with tetanus with age range 1-8 years, 12 males and 5 females. Seven of them had no tetanus immunization dan the rest of children with immunization never got booster immunization . Twelve children had otitis media and 5 children had untreated wound on their lower extremities as focus of infections. Period of getting wounded until symptoms appeared is approximately 3 days to 1 month.Common symptoms are trismus, convulsion, fever, opistotonus in all children. Complications such as bronchopneumonia occurred in 5 children, 4 children with severe tetanus and complications died in 19 hours to 18 days of treatment and the rest of 8 children had no complications.Conclusions.  Tetanus in children remains as health problem. Promoting prevention awareness in community and health providers is very important to decrease tetanus mortality and morbidity in children.
CORRELATION BIOFILM WITH INFECTION: IMPLICATIONS FOR PUBLIC HEALTH AND STRATEGIES TO CONTROL Purbowati, Rini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 5, No 1 (2016): Edisi Maret 2016
Publisher : Universitas Wijaya Kusuma Surabaya

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Biofilms are formed in the surfaces of mucosal of the body cavity can be a major source of infection . Infection by microbial biofilm formers are difficult to treat because of their greater resistance to antimicrobial agents than individual cells . Therefore biofilm -related infections and increased the economic burden of the country. The purpose of this literature review is to examine literature on biofilms and biofilm-associated microbes and their contribution to the disease burden of man with the aim of drawing attention to their public health implication.Biofilm are defined as “collections of microorganisms and their associated extracellular products at an interface and generally attached to a biological and non-biological substratum. Biofilm formation are influenced by factors controlling cell attachment, nature of surface, propertis of medium, and properties of the microbial cell surface. The ability of biofilm formation is genetically regulated by ica ABDC operon. Biofilm life cycle include adhesion of cells, formation of microcolonies, formation of biofilm and detachment anddispersal of biofilm. Structure of biofilm consists microorganisms and extracellular polymeric substances with vertical structures of microorganisms sometimes take the form of towers or mushrooms which are separated by interstitial spaces. Bacterial biofilm showed increased resistance to antibiotics, disinfectants and resistant to phagocytosis and other mechanisms of innate and adaptive immune system. Biofilms associated with food borne illness and affect to food security. Biofilms have been implicated in a wide variety of microbial infections in the body such as as urinary tract infections, catheter infections, middle-ear infections, formation of dental plaque, gingivitis, legionellosis ,infections involving contact lenses, and less common but more lethal processes such as endocarditis, infections in cystic fibrosis, and infections of permanent indwelling devices such as joint prostheses and heart valves. It is important for government agencies with a mandate for safeguarding public health and environment to develop and adopt ap propriate health risk assessment and biofilm-specific guidelines that are protective of both public health and the environment.
EFFECT OF GARLIC EXTRACT ON SMALL INTESTINE TO INCREASE INTERFERON γ IN WHITE MALE BALB/C MICE Sunaryati, Titiek
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 2 (2012): Edisi Oktober 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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     Common cold is an infectious disease that is caused by viruses. The purpose of this study is to explain how garlic extract can increase body  immunity.     This was experimental study using white male BALB/c strain mice, 10 weeks old with bodyweight of 25-35 grams. Group 1 received placebo (CMC Na) for 14 days. Group 2 received 10mg/kg BW garlic extract for 14 days, and group 3 received 20mg/kg BW garlic extract for 14 days. After 14 days mice were sacrified then  intestines were removed and processed in the paraffin block, then were stained with immunohistochemistry.     There was one  variable such as the amount of cell that produce interferon γ. Data were analyzed by analysis of variance Brown Forsythe, any significant different was further analyzed by using Games Howell in the significant level of 0.05. There were significant difference between groups those received placebo, 10mg/kgBw garlic extract, and 20mg/kgBw garlic extract in each variables.     Garlic extract can increase body immunity via increase in the amount of cell that produce interferon γ. 
FREQUENCY OPTIMIZATION OF WAVE EXPOSURE AND DOSE TO KILL ultrasonic mosquito larvae Mansyur, Mas; Rianti, E. Devi Dwi; Setiawan, Heru
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

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Mosquito is the one of inflicted insect upon people caused by the lead pard in many indescribable diseases such as malaria, dengue and cikungunya. Mosquito is bring problem for living space especially in decreasing sanitation such flooded area. The disease prevention caused by Mosquito has done in many ways among the others by using insecticide such as DDT, BHC, etc. Insecticide enable to caused poisoned to people and others living creatures. Using uncontrolled insecticide will be give high risk complex. It is a good idea to get a better alternative method. The ultrasonic waves choose as alternative method for its effectiveness and environmental friendliness. The focus of research has been done to have optimum frequency of ultrasonic waves caused highest lethal percentage and to get the dosages or the volume density of energy of ultrasonic waves to destroy Mosquito larva on the whole. As the result of observation and data analysis has done by 50 Mosquito Larva and 50 W ultrasonic powered give the optimum frequency is 86 KHz, with Lethal Percentage is 78%. Besides, is getting the linier relation ship to volume, so that the volume density of energy is 3.95904 kJ/ml.
MOTION APPEARANCE OF WOMEN IN THE MENSTRUAL AND ENDOMETRIAL CYCLE Hadi, Santika Rentika
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 2 (2014): edisi Oktober 2014
Publisher : Universitas Wijaya Kusuma Surabaya

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In the endometrium and menstrual cycle, occurs several phase. Those are Menstrual Phase, Proliferative Phase, Secretaory Phase and Phase Ischemi. In the these phase occurs change in outpouring of sex hormones (estrogen and progesterone) that are closely related to the psychological condition (stress and emotions). Psychological conditions in these cycles is estimated to affect the appearance of human motion, appearance of motion in motor skills which means the ability to bring maximum results with spends certain minimum energy and time. The aim of this research was to reveal differences in the appearance of motion in the 200-meter run at the menstrual cycle and endometrium phase. Result of the statistical analysis showed that the appearance of motion in the form of 200-meter run in the fourth group of the menstrual phase, proliferative phase, secretory phase, and ischemic phase has no significant difference (P> 0.05). The conclusion of this research there was no differences in the appearance of motion (travel time to run 200 meters) in a woman in a state of menstrual phase, proliferative phase, secretory phase, and ischemic phase.

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