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Jurnal Ilmiah Kedokteran Wijaya Kusuma
ISSN : 19782071     EISSN : 25805967     DOI : -
Core Subject : Health, Science,
Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.
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Articles 340 Documents
THE GIVING EFFECTS OF BISCUITS AND TEMPEH-BASED FLOUR CAKES AS SUPPLEMETARY FEEDING TOWARDS IMPROVEMENTS IN BODY WEIGHT AND HEIGHT IN CHILDREN SUFFERING MALNUTRITION 2015 Rizky, Oktovina; Wirjatmadi, Bambang; Adriani, Merryana
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 1 (2015): edisi September 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Background: Nutritional problem in children is considered as a major issue and one that should receive priority in treatment is concerning to malnutrition. Malnutrition in children occurs due to insufficiency in energy and protein. Energy and protein are required in supporting rapid growth in children.Objective: to learn the giving effects of biscuits and tempeh-based flour cakes as supplementary feeding towards improvements in body weight and height of children under five suffering malnutrition in one of Public Health Center working area, northern region of Kediri Municipality.Methods: This study used a Randomized Control Triall Design, towards groups of children under five by providing tempeh-based flour cakes for supplementary feeding in the treatment group and by providing biscuits for supplementary feeding in control group. Samples were as many as 30 children under five and the data were being analyzed using peason and pre-post differences analysis was done using paired samples T-testResult: There was significant difference between body weight and body height after  provision of providing biscuits and tempeh-based flour cakes for supplementary feeding with  p = 0.001 (p <α) for the treatment group and p = 0.001 (p <α) for the control group.Conclution: Providing and tempeh-based flour cakes in the treatment group for 30-days gave influence on increasing body weight and height.
INTERLEUKIN-6 (IL-6) LEVEL AS AN INDIKATOR OF PROGRESIVITY RHEUMATOID ARTHRITIS (RA) DISEASE Tania, Putu Oky Ari; Simamora, Dorta; Parmasari, Wahyuni Dyah; Rahmawati, Febtarini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

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Rheumatoid Arthritis (RA) is autoimmune disease that attacks joints and synovial tissues. Rheumatoid Arthritis is characterized by inflammation that involves production of cytokines such as Interleukin 6 (IL-6). Increasing of interleukin 6 has correlation with activity and progressivity of the disease. This research was designed to know whether IL- 6 could be used as indicator progressivity of RA. The method that used for measuring IL-6 level is ELISA (Enzyme Linked Immunosorbent Assay), using the principle antigen-antibody binding. In early stage there were 9 persons (S01, S02, S03, S04, S07, S08, S09, S10 and S14) with of IL-6 level (mean : 3.640 pg/mL), intermediate stage there were 3 persons (S06, S13 and S15) with IL-6 level (mean : 12.453 pg/mL), late stage : 3 persons (S05, S11 and S12) with IL-6 level (mean : 59.349 pg/mL).
THE PATHOPHYSIOLOGY RELATIONSHIP OF HYPERTENSION AND RENAL HYPERTENSION Kadir, Akmarawita
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 5, No 1 (2016): Edisi Maret 2016
Publisher : Universitas Wijaya Kusuma Surabaya

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Introduction : Hypertension is a disease with an incidence rate is still high around the world, most of the causes of hypertension is unknown (essential hypertension / primary hypertension), a small portion of hypertension caused by diseases acquired (secondary hypertension). The unknown cause of Hypertension causing complications of diseases that worsen it, eg kidney disease (renal disease), and can be a disease that actually cause hypertension becomes more severe (secondary hypertension). Pathophysiology of essential hypertension has been a lot of discussed, but the pathophysiology of renal disease which causes hypertension still needs to be explored, particularly on the relationship between primary hypertension and secondary hypertension (hypertension, kidney or renal hypertention). Kidney disease is a disease that cause hypertension via the mechanism of resistance increases blood circulation to the kidneys and a decrease in the glomerular capillary function which resulted in the release of an important substance-substance such as renin, angiotensinogen, angiotensin I, angiotensin II, angiotensin converting enzyme (ACE) inhibitors, aldosterone, bradykinin, nitric oxide (NO), which in turn causes increase blood pressure (hypertension). Hypertension proved to be a feedback mechanism to suppress the high renin, renin suppression doesn’t mean anything if kidney disease not treated properly, and even cause permanently hypertension or even getting worse. The purpose of this article was to determine the pathophysiology of hypertension, renal hypertension in particular, and how the relationship between hypertension and renal hypertension (secondary).
ASPEK LABORATORIUM Acute Promyelocytic Leukemia (APL) AML-M3 Rahmawati, Febtarini
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2013): Edisi Mei 2013
Publisher : Universitas Wijaya Kusuma Surabaya

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Acute Promyelocytic Leukemia (APL) adalah subtipe M3 dari Acute Myelogenous Leukemia (AML), sesuai klasifikasi French-American-British (FAB). APL mempunyai beberapa varian yang bisa dibedakan dari pemeriksaan molekular dan sitogenetika. Lebih dari 95% APL hipergranular (M3 klasik), 15%-20% dari APL adalah varian mikrogranular (hipogranular, M3v) dan varian APL yang jarang (<1%) adalah basofilik dan Promyelocytic leukemia zinc finger        (PLZF/M3r).Gejala klinis penderita APL yakni anemia meliputi pusing, kelelahan, sesak ketika kerja fisik, pucat. Perdarahan terjadi karena pasien dengan APL mengalami penurunan jumlah trombosit dan gangguan sistem koagulasi. Sel darah putih pada umumnya meningkat ditandai dengan gejala panas badan dan infeksi serta pembesaran limpa juga nyeri tulang akibat infiltrasi sel-sel leukemia ke periosteal.Tes skrining penderita leukemia akut adalah pemeriksaan darah rutin dan evaluasi sediaan hapusan darah tepi. Pemeriksaan penunjang diagnostik lainnya adalah hapusan dari aspirasi sumsum tulang, pengecatan sitokimia, Immunophenotyping, sitogenetika dan biologi molekular. White blood cell (WBC) > 10 X 109/L, trombositopenia < 50 X 109/L. Hapusan darah tepi pasien dengan APL didapatkan gambaran eritrosit normokromik normositik dengan poikilositosis dan kadang-kadang normoblas. Gambaran sel-sel muda didominasi oleh promielosit. Sebagian besar hipergranular, morfologi mieloblasnya dengan nukleus berlekuk dan Auer rod. Pada hapusan sumsum tulang umumnya hiperseluler dengan jumlah sel-sel muda promielosit ≥30%. Morfologi promielosit pasien dengan APL lebih besar daripada promielosit normal. Auer rods positif kadang-kadang didapatkan faggots cell. Aktivitas eritropoiesis dan trombopoiesis tertekan. Varian hipergranular APL diketahui dengan pemeriksaan sitokimia, immunophenotyping, sitogenetika dan teknologi biologi molekuler.
THE EFFECT OF CLIMATE ON DEVELOPMENT VARIABILTAS Water-borne diseases Sudarso, Sudarso
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

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Global warming issue in 21 century this become especial issue. The effect of global warming besides at another phenomenon, like floods, erosion, dryness, increasing temperature of earth, climate change and also its influence to human being, especially for health. Climate change is expected to have considerablke impact on health, and one of the most important is waterborne diseases. Weather influences the transport and dissemination of the microbial agents via rainfall and runoff and survival and/or growth such factors as temperature. Knowledge about transport processes and fate of microbial pollutants associated with rainfall and snowmelt is key to predicting risk from change in weather variability. Water-borne diseases can be infected by many routes of exposure, as well as individual or population susceptibility, to waterborne pathogens, with water quality, avaibility, sanitation, and hygiene all playing a role.More than 100 types of pathogenic bacteria, viruses, and prozoa can be found in contaminated water.
PERFORMANCE OF THE ACTIVE SIAGA VILAGES AT THE AREA SUKODONO COMMUNITY HEALTH CENTRE Noviana, Ayu Cahyani
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 2 (2014): edisi Oktober 2014
Publisher : Universitas Wijaya Kusuma Surabaya

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In relation to be built “Healthy District”. Sukodono Community Health Centre wanted to evaluate all of the Siaga Villages performance at the area and tried to be upgraded the rank , if possible to be at the best rank. The result showed that at 2013 there was no more first grade Siaga Villages, 52.63% became second grade and 10,53% became third grade but the highest grade was none. To achived the highest grade was very difficult due to limited human resources at the village, so Sukodono Community Health Centre has to do some workshops and gives some rewards to the villagers to attrack them to become the participants
The influence of leaf infusion administration of Angelica keiskei with Simvastatin on lowering triglyceride levels in Rattus norvegicus Marentek, Cecilia Febriani; Ernawati, Ernawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 6, No 2 (2017): EDISI SEPTEMBER 2017
Publisher : Universitas Wijaya Kusuma Surabaya

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Ashitaba is one from many plant that contained flavonoid. Flavonoid is antioxidant that belong to phenols. If we compare between ahitaba and vitamin C, ashitaba have hundred times more effective than vitamin c and twenty-five more effective then vitamin E. Antioxidant may reduce cholesterol by inhibiting oxidation reaction so that cholesterol can be easily pass through the arteries and its plug. This research aims to know what is the influence of ashitaba (Angelica keiskei) assisting simvastatin  in lowering triglyceride levels in strain wistar white male rats (Rattus norvegicus) that in hypertriglycerid. The population on this research is strain wistar white rats (Rattus norvegicus), male, 100 g, 2 months age with health physical and total sample are 33 rats. The result from this research proved that there is no influence of ashitaba (Angelica keiskei) assisting simvastatin in lowering triglicyride levels in strain wistar white male rats (Rattus norvegicus) that in hypertriglycerid. It can caused by competituve reaction between ashitaba and simvastatin that they were blocking each other.
THE ROLE OF ZINC SULPHATE AND OMEGA 3 IN IMPROVING OF ALBUMIN LEVEL ON PULMONARY TUBERCULOSIS PATIENTS IN PARU HOSPITAL SURABAYA 2015 Durry, Fara Disa; Wirjatmadi, Bambang
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 1 (2015): edisi September 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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The epidemiology of Tuberculosis (TB) showed that TB is a disease which is associated with malnutrition. Malnutrition and lacking of certain essential nutrients required by immune system might cause immune function deficiency resulting higher susceptibility to bacterial and viral infections. There is positive correlation between immune system and high nutrient contents, such as Vitamin C, zinc, and antioxidants that brings good effect on infections, including Tuberculosis. One of the efforts conducted to help promoting improving albumin level on pulmonary tuberculosis patients is through zinc and sulphate provision followed by Omega-3 supplementation. This study was conducted in 2015 aimed to analyze the role of Zinc Sulphate Omega-3 provision in improving albumin level on pulmonary tuberculosis patients in Paru Hospital, Surabaya.This study applied randomized study design using Pre-test and Post-test Control group design on patients suffering pulmonary tuberculosis. This study was conducted by administering Zinc Sulphate and Omega-3 on treatment group and placebo on the control group. The samples of this study consisted of 20 pulmonary tuberculosis patients divided into two groups: treatment group and control group. Each group consisted of 10 patients. Statistical analysis was conducted using paired T-test and independent t-test. The results is There were significant differences in albumin level (p = 0.001) in the treatment group before and after supplementation Zinc Sulphate And Omega 3. While in the control group between before and after supplementation Zinc Sulphate And Omega 3 showed no significant differences in body weight (p = 0.224). The conclusions is Zinc Sulphate and Omega 3 plays a role in increasing albumin level respondents. There are significant differences on albumin level before and after supplementation Zinc Sulphate And Omega 3.
EFFECT OF ZINC ADMINISTRATION TOWARD TO DIFFERENCE OF INCREASING NUTRITION STATUS ON HIV / AIDS PATIENTS Sahadewa, Sukma
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Nutrition had the important role in patient with HIV/AIDS, it increased the immune system and delayed the progression of HIV into AIDS. Zinc played a role in optimizing immune function, especially in T cell, need for accelerating growth process, stabilized structure of cell membranes and activated growth hormone. The purpose of this study was to analyze the differences in weight and albumin levels after administration of zinc sulfate in patients with HIV/AIDS. This research is experimental research with randomized pretest posttest control group design with the provision of a double-blind treatment. Data collection techniques using questionnaire, food recall, food frequency questionnaire, anthropometry, blood sampling and laboratory examination. The results showed that there were significant differences in body weight between before and after zinc administration in the treatment group (p = 0.030), whereas in the control group showed no significant differences in body weight between before and after zinc administration (p = 0.839 ). T-test results of elevated levels of albumin difference between before and after zinc administration between the treatment and control groups showed that there were significant difference with p value = 0.673.
USE OF CLASSIFICATION AND REGRESSION TREE (CART) FOR CHRONIC PERIODONTITIS CLASSIFICATION IN DENTAL HOSPITAL OF HANG TUAH UNIVERSITY SURABAYA Maharani, Aulia Dwi
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Classification and Regression Tree (CART) is now commonly used as one of nonparametricclassification methods. The advantage of this method is it can effectively used on data whichhave many independent variables. It is also easy to be interoperated.The aim of this research is to classify Chronic Perodontitis in Dental Hospital of Hang TuahUniversity Surabaya using CART. The Chronic Periodontitis divided into 3 categories: mild,moderate, and heavy. Based on the analysis result, 2 factors can affected the mild type ofchronic periodontitis , 6 factors affected moderate type of chronic periodontitis and 8 factorsaffected the heavy type of chronic periodontitis.The criteria used to count the accuracy of the CART classification is 1-APER. The 1-APERscore shows a very good result which is 92,5% for data learning and 90% for data testing.

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