Paul L Tahalele
Faculty Of Medicine Widya Mandala Surabaya Catholic University

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CYANOTIC HEART DISEASE: AN OVERVIEW OF TETRALOGY OF FALLOT Laksono, Gerardo; Tahalele, Paul L
JOURNAL OF WIDYA MEDIKA JUNIOR Vol 4, No 2 (2022): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwmj.v4i2.3816

Abstract

Tetralogy of Fallot (TOF) is the most common cyanotic heart disease with anomalies consist of: ventricular septal defect (VSD), overriding aorta, pulmonary stenosis and hypertrophic of the right ventricular. It also has various anomalies type such as TOF with absent pulmonary valve, TOF with pulmonary atresia, TOF with atrioventricular septal defect, TOF with coronary artery anomalies, etc which will be discussed in detail. Proper diagnosis is required when dealing with the TOF continue with radiological examination. Adequate history taking and correct physical examination are necessary in dealing with congenital heart defects, especially TOF case. In this overview, we also discuss about the comprehensive management, from tet spell management, palliative management of TOF that required shunt with various technique, and surgical total corrective of TOF with many approach such as transannular accompany with right ventriculotomy or transatrial with transpulmonary or beating heart surgery technique to prevent reperfusion injury complication.
When Do We Need Pleural Surgery? Paul L Tahalele; Merlinda Dwintasari; Y Motulo; Yan Efrata Sembiring; Dhihintia Jiwangga Suta
JURNAL WIDYA MEDIKA Vol 5, No 2 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1276.928 KB) | DOI: 10.33508/jwm.v5i2.2200

Abstract

Pleural sac is an enclosed sac covering the lung that consist of two membranes, i.e. parietal and visceral pleura. It has a cavity filled with small amount fluid that plays important role to provide smooth sliding of lung during respiration. Change or disturbance in the pleural cavity and or the pleura itself may result in restriction of lung expansion causing ventilation compromise. Pathology of pleura may result from varying etiology. It may present as inflammatory pleural effusion, non-inflammatory pleural effusion, pneumothorax, hematothorax, fibrothorax, pleural tumors, and cylothorax. Diagnostic tool for pleural diseases may be made from the simplest chest x-ray, ultrasound, computed tomography, MRI and histopathological studies. There are several treatment options for managing pleural diseases. It consist non operatif treatment, pleural drainage, decortication or pleurectomy, pleurodesis, and/ or resection of pleural tumor through procedure VATS, or open thoracotomy. Indications for surgery are traumatic or spontaneous pneumothorax, hematothorax, cylothorax, failure of non operatif treatment, fibrothorax or schwarte limiting lung expansion, mesothelioma, and recurrent pneumothorax or malignant pleural effusion. Decision for surgery need appropriate timing and planning regarding different pathology and different etiology.
Pemakaian Nitroglycerin Intravena Invivo Sebagai Antidotum Efek Heparin Dhihintia Jiwangga; Paul L. Tahalele; Achmad Basori
JURNAL WIDYA MEDIKA Vol 4, No 2 (2018)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (575.802 KB) | DOI: 10.33508/jwm.v4i2.1813

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Introduction: intravenous nitroglycerin, if given simultaneously with heparin, can obstruct the heparin's anticoagulant effect, but it still remains controversy. This statement underlies researcher to authenticate whether intravenous nitroglycerin can neutralize heparin Aim: to find out if intravenous nitroglycerin can neutralize heparin Method: this research is an in vivo experiment with a rabbit as the experimental subject at The Pharmacology Department of The Medical Faculty of The Airlangga University. The experimental subjects are divided into a control group and a treatment. The control group is only given a dose of heparin, while the treatment is given a dose of heparin and some doses of intravenous nitroglycerin. Each of this experimental subjects will be examined its activated clotting time (ACT) score with a hemochrone. The statistical test that will be used is the normality test with one sample kolmogorov smirnov test Result: the administration of 3 mg/kg dose of intravenous glyceryl trinitrate after the administration of 3 mg/kg heparin can reduce the ACT value or neutralize the heparin's anticoagulant effect significantly with the value p= 0,001 (pc0,005). The group that receives 6 mg/kg glyceryl trinitrate, if compared to the prior ACT before the administration of 6 mg/kg glyceryl trinitrate, has a change with the value p= 0,001 (PO, 05). The group that receives 9 mg/kg glyceryl trinitrate, if compared to the prior ACT before the administration of 9 mg/kg glyceryl trinitrate, has a significant change with p=0,010 (P
Pneumomediastinum Paul L Tahalele; Merlinda Dwintasari; Y Motulo; Yan Efrata Sembiring; Dhihintia Jiwangga Suta
JURNAL WIDYA MEDIKA Vol 5, No 2 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1154.558 KB) | DOI: 10.33508/jwm.v5i2.2201

Abstract

Mediastinum is defined as the area demarcated by the thoracic inlet superiorly, the diphragm inferiorly, and the pleural cavities laterally. The mediastinum is a division of the thoracic cavity that contains thymus gland, the heart, trachea and portions of the seophagus, and other structures. Mediastinum divided into 3 region, anterior, posterior, superior, and middle regions. Pneumomediastinum or emphysematous mediastinum is existence of free air in the mediastinum due to spontaneous or secondary reasons. That can be confirmed with thorax X-Ray or CT- Scan thorax. The symptomps are severe central chest pain, shortness of breath, subcutaneous emphysema, laboured breathing and voice distortion. In physical diagnosis, especially on auscultation, there is spesific sign called “Hamman’s Crunch” (crunching sound corresponding with the cardiac cycle (Hamman’s Crunch). Pneumomediastinum can leadto pneumopericardium, pneumotoraks, penumoretroperitonium or penumoperitonium. Air in the mediastinal cavity can be absorbed by itself slowly, so penumomediastinum can treated non-operatively.
TELEMEDICINE AS AN OPTION FOR HEALTH SERVICE LIMITATIONS IN COVID-19 PANDEMIC ERA Bernadette Dian Novita; Sianty Dewi; Evelyn Ongkodjojo; Agatha Christi Palupi; Immanuel Michael; Paul L. Tahalele
JURNAL WIDYA MEDIKA Vol 7, No 2 (2021): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v7i2.3430

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Coronavirus disease 2019 (COVID-19) pandemic era provides a new habit in form of self-quarantine or physical distancing. The recommendation is to delay visits to health facilities if it is not in the emergency condition to slow down the spread of COVID-19 transmission. This study aims to develop a telemedicine system that integrates three main components, namely doctors, patients, and hospital management in Gotong Royong Hospital Surabaya to minimize the transmission of COVID-19 while still provides comprehensive health services. The development of telemedicine service is divided into 3 stages. In the first stage, emergency screening was carried out by developing Frequently Asked Questions (FAQs). The second stage was continued with prototype testing and the last part was improving the system to create a better referral system. Gotong Royong Hospital telemedicine has been active since June 2021, within 2 months, 45 patients are willing to use telemedicine services. The results showed that telemedicine was easily accepted by patients in internal medicine clinic services (p
AN ANIMATED MODELS DEVELOPMENT OF CARDIOVASCULAR SYSTEM IN PHARMACOLOGY LEARNING MODULE FOR MEDICAL STUDENTS Bernadette Dian Novita; Paul L Tahalele; Gerardo AK Laksono
JURNAL WIDYA MEDIKA Vol 7, No 1 (2021): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v7i1.3168

Abstract

Hypertension is the most known common cardiovascular disease. Based on the Indonesian Competency Standard of Medical Doctors (StandarKompetensiDokter Indonesia or SKDI), the management of essential hypertension is at 4A or the highest level. Therefore, doctors should be able to establish a complete and independent diagnosis and management. The student passing rate in the cardiovascular system at the undergraduate level of medical education of Faculty of Medicine Widya Mandala Catholic University (FK UKWMS) was around 60-70%. This study is an evaluation to develop learning methods that would improve student learning outcomes. The development of this animation model is aimed to increase the engagement process in Pharmacology learning, especially in the cardiovascular system. 98 active students participated in this study, divided into 74 undergraduate students and 24 clinical internship students. The evaluation was carried out using a pre-test and a post-test related to pharmacological animation video exposure. Using the Wilcoxon different test, there was a significant difference between the pre-test and post-test results, especially in the clinical internship program’s students. This animated model was expected to help students to determine the rational determination of hypertension therapy.
COMPLETE REPAIR OF TETRALOGY OF FALLOT (TOF) ON BEATING HEART SURGERY WITHOUT AORTIC CROSS CLAMPING : REPORT OF A CASE Gerardo AK Laksono; Heroe Soebroto; Paul L Tahalele
JURNAL WIDYA MEDIKA Vol 7, No 2 (2021): October
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v7i2.3516

Abstract

Introduction: Reperfusion injury is a well-known phenomenon that occurred in cardioplegic techniques with cardiopulmonary bypass. Therefore great effort is made to prevent reperfusion injury. Beating Heart Continuous Coronary Perfusion (BHCCP) surgery is one of the alternative techniques to improve an ischemic reperfusion injury in open-heart surgery, either in pediatric or in adult. This technique can be done in complete repair of tetralogy of Fallot (TOF). Purpose: To report our first experience in doing complete repair of TOF using beating heart technique without aortic cross-clamping Case Report: A five-year-old boy came on to ER on January 6th, 2012, with a history of cyanotic since birth. His echocardiography and catheterization concluded a tetralogy of Fallot with a McGoon ratio of 1.95 (the diameter of RPA and LPA were 9.14 mm and 8.79 mm, respectively). A complete repair of TOF was done using beating heart surgery without aortic cross-clamping technique. One month post-surgery evaluation, there weren't any neurological or motor disorders. Echocardiography results showed no residual pulmonary stenosis, but 0.2 mm residual VSD was found. Conclusion: This heart rate technique is an alternative method of myocardial protection in cardiac surgery. In several cardiac centres globally, this technique is relatively safe and can be used during surgery, especially in the total correction of TOF.
COVID-19 PATIENTS’ CHARACTERISTIC IN COVID-19 REFERRAL HOSPITAL, SURABAYA, INDONESIA Titiek Ernawati; Nunung Nugroho; Bernadette Dian Novita; Paul L Tahalele; Niluh Suwasanti; Epriyanto T Darmadi; Kevin Anggakusuma Hendrawan; Albert Setiawan; Audrey Fedora Irawan; Alyssa Claudia Valerie Gunawan; Claudia Tjipto; Kevin Samsudin; Ferdinand Erwin; Gerardo Axel Ruslie; Nevan Go; Melvin F Gonga
Jurnal Berkala Epidemiologi Vol. 10 No. 1 (2022): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V10I12022.48-57

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Background: Coronavirus 2019 (COVID-19) is a global pandemic with various clinical manifestations and is affected by multifactor. Epidemiological data of COVID-19 in Indonesia, especially in Surabaya have not been well established yet. Purpose: This study aims to provide the COVID-19 patients profile in Surabaya City, Indonesia. Method: The study data were retrospectively collected from electrical medical records in Primasatya Husada Citra (PHC) Hospital of Surabaya, one of the referral hospitals for COVID-19 in Surabaya. Descriptive and Spearman correlation statistics were done for data analysis. Results: Between 1 July – 31 August 2020, 456 subjects were diagnosed positive for COVID-19 by real-time polymerase chain reaction and enrolled in the study. Study subjects were dominated by the group age of 21-30 (26.75%), male (60.30%), living in East Surabaya (16.22%), and mild to moderate disease severity (47.59%) according to the patient’s clinical manifestation, respiration rate, and peripheral oxygen saturation. Subjects with symptoms were majorly having cough (37.93%), fever (29.38%), malaise (28.07%), and dyspnoea (25.00%). Positive correlation was found between disease severity and group of age (r=0.35; p=0.01), gender (r = 0.13; p=0.01), comorbidities (diabetes mellitus, hypertension, and cardiovascular disease), and X-ray findings (r=0.14; p=0.02). A negative correlation was found between disease severity and the region of domicile (r=-0.15; p=0.01). Conclusion: This epidemiological data of COVID-19 patients in Surabaya city, Indonesia, may help in diagnosing COVID-19 patients and improving health management strategies during a pandemic. Patients need to be aware of COVID-19 and understand disease transmission, especially with symptoms and risk factors.
Perbandingan Performansi Algoritma Pengklasifikasian Terpandu Untuk Kasus Penyakit Kardiovaskular Adi Nugroho; Agustinus Bimo Gumelar; Adri Gabriel Sooai; Dyana Sarvasti; Paul L Tahalele
Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Vol 4 No 5 (2020): Oktober 2020
Publisher : Ikatan Ahli Informatika Indonesia (IAII)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (477.038 KB) | DOI: 10.29207/resti.v4i5.2316

Abstract

One of the health problems that occur in Indonesia is the increasing number of NCD (Non-Communicable Disease) such as heart attack and cardiovascular disease. There are two factors that cause cardiovascular disease, i.e. factor that can be changed and cannot be changed. This study aim to analyze the best performance of several classification algorithms such as k-nearest neighbors algorithm (k-NN), stochastic gradient descent (SGD), random forest (RF), neural network (NN) and logistic regression (LR) in classifying cardiovascular based on factors that caused those diseases. There are two aspects that need to be examined, the performance of each algorithm which is evaluated using the Confusion matrix method with the parameters of accuracy, precision, recall and AUC (Area Under the Curve). The dataset uses 425.195 samples from result data of cardiovascular disease diagnosed. The testing mode uses percentage split and cross-validation technique. The experimental results show that the performance of NN algorithms produces the best prediction accuracy compared to other algorithms, which is accuracy of 89.60%, AUC of 0.873, precision of 0.877, and recall of 0.896 using percentage split and cross-validation testing mode using Orange. For the accuracy of 89.46%, AUC of 0.865, precision of 0.875, and recall of 0.895 using cross-validation testing mode using Weka. By KNIME, the result of accuracy value is 88.55%, AUC value is 0.768, precision value is 0.854, and recall value is 0.886 using cross-validation testing mode.
Neutrophil gelatinase-associated lipocalin as a biomarker for acute kidney injury in children after cardiac surgery Meta Herdiana Hanindita; Riskky Vitria Prasetyo; Ninik Asmaningsih Soemyarso; I Ketut Alit Utamayasa; Paul Tahalele
Paediatrica Indonesiana Vol 56 No 4 (2016): July 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (346.772 KB) | DOI: 10.14238/pi56.4.2016.230-7

Abstract

Background Acute kidney injury (AKI) is still diagnosed by measuring the estimated creatinine clearance (eCCl), despite the fact that it may not change until 50% or more of kidney function has been lost. AKI after cardiac surgery is related to prolonged intensive care, decreased quality of life, and increased long term mortality. Neutrophil gelatinase-associated lipocalin (NGAL) represents an early biomarker of AKI, which may be useful for assessing AKI in cardiac patients.Objective To determine the validity of urinary and plasma NGAL as biomarkers for AKI in children after cardiac surgery.Methods Subjects were children who underwent cardiac surgery in Dr. Soetomo Hospital, Surabaya, Indonesia from August 2013 to January 2014. Serial urine and blood samples were analyzed for NGAL before surgery, as well as at 2h, 4h, 12h, and 24h after surgery. The AKI was established based on pRIFLE criteria. Estimated creatinine clearance (eCCl) was calculated from the estimated glomerular filtration rate (eGFR), according to age by the traditional Schwartz formula. Serum creatinine was assayed by the Jaffe method before surgery, as well as at 12h, 24h, 48h, and 72h after surgery.Results Of 20 subjects, 5 developed AKI. Urinary and plasma NGAL increased markedly at 2h postoperatively, as compared to eGFR which showed a rise at 12-48 h after cardiac surgery. Analysis of 2h post-operative urinary NGAL at a cut off value of 11.270ng/mL yielded an area under the curve (AUC) of 1.00 (95%CI 2.63 to 12.13), with sensitivity and specificity of 100% each for AKI. In addition, 2h post-operative plasma NGAL at a cut off value of 8.385 ng/mL yielded an AUC of 1.00 (95%CI 3.71 to 12.15) with sensitivity and specificity of 100% each for AKI.Conclusion Urinary and plasma NGAL are valid as early biomarkers for AKI in children after cardiac surgery.
Co-Authors Achmad Basori Adi Nugroho Adri Gabriel Sooai Agatha Christi Palupi Agustinus Bimo Gumelar Albert Setiawan Alyssa Claudia Valerie Gunawan Andre Young Anggorwasito, Jose L Anggowarsito, Jose L Arief, Teuku Audrey Fedora Irawan Bernadette Dian Novita Bernadette Dian Novita Bernadette Dian Novita Bernadette Dian Novita Bernadette Dian Novita Dewi Budipramana, Edwin Claudia Tjipto Daniel DH Silitonga Delvi Vorst Dhihintia Jiwangga Dhihintia Jiwangga Suta Dhihintia Jiwangga Suta Dian Putri, Maria Patricia Dorothea Kusumaningrat Dyana Sarvasti Ellenora R Mustikaningrat Ellenora R Mustikaningrat Epriyanto T Darmadi Erwin, Ferdinand Evan Ricardo Evelyn Ongkodjojo Febianingrum, Adhani Ferdinand Erwin Gerardo AK Laksono Gerardo AK Laksono Gerardo AK Laksono Gerardo AK Laksono Gerardo Axel Ruslie Gerardo Laksono Harijati, Erna Hendrawan, Kevin Anggakusuma Herman YL Wihastyoko Heroe Soebroto Huang, Velinda Hutama, Andreas MS I.G.A.P.D Dewi Immanuel Michael Irene L Parengkuan Jose L. Anggowarsito Joseph, Herman Jovan Amadeo Kartana, Kartana Kevin Samsudin Kevin Samsudin Khoesasih, Antonius Kevin Laksono, Gerardo Laksono, Gerardo AK M. Nahak, Belinda Peregrina Maria S Ganggur Melvin F Gonga Merici, Angela Merlinda Dwintasari Merlinda Dwintasari Meta Herdiana Hanindita Mitchell Theny Motulo, Yosis Y Nevan Go Ni Nyoman Ratih Dharmapatni Niluh Suwasanti Niluh Suwasanti Ninik Asmaningsih Soemyarso Noorlaksmiatmo, Harno Prihadi Nunung Nugroho Oktavianus Y Ampur Oktavianus Y Ampur Rahayu, Titien Ricardo, Henry Riskky Vitria Prasetyo Sianty Dewi Sianty Dewi Sianty Dewi Suwasanti, Niluh Theresia Cindy Limantoro Titiek Ernawati Tridharmadi, Epriyanto Wahyuni Widoretno, Elisabeth Tri Wihastyoko, HYL Wilson Christianto Khudrati Wismaya, IGP Wegen Y Motulo Y Motulo Yan Efrata Sembiring