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Antioxydant Extract of Endophytic Fungi Fusarium oxysporum LBKURCC41 Marlinda, Sri; Teruna, Hilwan Yuda; Pratiwi, Nova Wahyu; Ardhi, Aulia; Saryono, Saryono
Jurnal Natur Indonesia Vol 17, No 2 (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (416.485 KB) | DOI: 10.31258/jnat.17.2.1-9

Abstract

Fusarium oxysporum LBKURCC41 is one of endophyte fungi which is  able to produce secondary metabolites. The purpose of this research was to discover an antioxidant agent from F. oxysporum LBKURCC41extract that was fermented in Huang medium for 15 d with of corn and potato with particle size of 80 mesh as carbon sources. The ethyl acetate extract from the cultured medium showed four dominant component with retentiont time of 3.24, 3.44, 17.02 and 18.889 min. The F. oxysporum LBKURCC41 extract containing compounds with functional group O-H, C-H and C-O, and it had  a IC50 value of 435,157±12,009a.
Clinical Characteristics of Diabetic Retinopathy Patients in Eye Clinic of Zainoel Abidin General Hospital Banda Aceh, Indonesia Zaini, Lia Meuthia; Marlinda, Sri; Budiman, Annisa Meivira
Journal of Epidemiology and Public Health Vol 5, No 4 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.679 KB)

Abstract

Background: Diabetic retinopathy (DR) is one of the most frequent microvascular compli-cations of diabetes mellitus (DM). The increasing number of diabetic retinopathy cases, amajor cause of blindness worldwide, is resulted from the increasing prevalence and life span of diabetes mellitus patients. In 2010, the number of diabetic retinopathy cases was 126.6 million and is predicted to increase to 191.0 million by 2030. The number of patients with visionthreatening diabeticretinopathy is also predicted to increase from 37.3 million to 56.3 million.Subjects and Method: This study was a descriptive study conducted from January to February 2020.A sample of 98 patients was taken through fixed disease sampling. Research data was collected from electonic medical record of patients visiting Eye Clinic of Zainoel Abidin General Hospital Banda Aceh using total sampling method. The researchers used the triangulation method to complete some missing demographic data in the medical records, such as occupation, education, and monthly salary. Interviews were conducted directly with patients after they underwent an examination, and the results were included in the research form. Results: 35 patients (35.7%) were aged 56-65 years and 26 patients (26.5%) worked as house-wives. The most common systemic complications were heart disorder found in 17 patients (17.3%). Proliferative diabetic retinopathy (PDR) was identified in 49 patients (50.0%), whereas 51 patients (52.0%) presented with diabetic macular edema (DME). 44 patients (44.9%) came with less than 6/60 visual acuity on the left eye.Conclusion: Most patients presenting in Eye Clinic of Zainoel Abidin Hospital Banda Aceh were in worse condition (PDR) with visual acuity of less than 6/60. Therefore, educating and counseling diabetic patients to undergo routine screening by ophthalmologists are important in order to prevent loss of vision caused by diabetic retinopathy.Keywords: clinical characteristic, diabetic retinopathyCorrespondence: Lia Meuthia Zaini. Department of Ophthalmology, Faculty of Medicine, Universitas Syiah Kuala/ Dr. Zainoel Abidin hospital. Jl. Tgk. Daud Deureueh 108, Banda Aceh, Indonesia. Email: liamzaini@unsyiah.ac.id. Mobile: +6282266891502.Journal of Epidemiology and Public Health (2020), 05(04)https://doi.org/10.26911/jepublichealth.2020.05.04.12