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All Journal Jurnal Agroindustri Media Farmasi Jurnal Pengabdian Kefarmasian
Khairi, Nur
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Electrical & Electronics Engineering Energy Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health

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FORMULASI GRANUL INSTAN EKSTRAK BUAH BUNI (Antidesma bunius L.) SEBAGAI MINUMAN ANTIOKSIDAN Khairi, Nur; Sapra, Amriani; Tawali, Suryani; Indrisari, Maulita
Jurnal Agroindustri Vol. 14 No. 1 (2024): May 2024
Publisher : BPFP Faperta UNIB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31186/jagroindustri.14.1.1-10

Abstract

Buni is a plant that is widespread in Asia, especially Indonesia. Buni fruit has been reported to contain anthocyanins which have activity as flavonoids, antiocyanins, saponins, alkaloids and as high antioxidant agents, but because Buni fruit is seasonal so raw materials depend on the season, therefore to increase availability it needs to be extracted and formulated in a form preparations. The purpose of this study was to obtain an instant granule formula that meets the physical characteristics and to determine the IC50 value of the antioxidant activity of the instant granule preparation of buni fruit extract (Antidesma bunius L.). The extract was prepared by extraction method using 70% ethanol solvent with the addition of 3% citric acid for 3x24 hours. Instant granules were prepared using the wet granulation method using varying concentrations of PVP as a binder, namely 1%, 3% and 5%. Furthermore, the physical characteristics were evaluated including flow properties, moisture content, soluble time, then antioxidant activity was determined based on the IC50 value using the DPPH method. The results showed that F1 and F2 had good flow properties and F3 had very good flow properties, the moisture content was around 2-4% and the dissolution time was 2-3 minutes. Based on the test results obtained formula 3 with a PVP concentration of 5% is a formula that meets the physical requirements of granules and an IC50 value of 65.94 µg/mL is included in the strong antioxidant category.
Efektivitas Ekstrak Daun Kelor (Moringa oleifera L.) Untuk Ulkus Peptikum Pada Tikus Putih (Rattus norvegicus) Yang Diinduksi Aspirin Indrisari, Maulita; Khairi, Nur; Muslimin, Lukman; Awaluddin, Akbar; Arisah, Arisah
Media Farmasi XXX Vol 19, No 1 (2023)
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar, Kementerian Kesehatan RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v19i1.3292

Abstract

Effectiveness of Moringa Leaf Extract (Moringa oleifera L.) for Peptic Ulcuses In Aspirine-Induced White Rats (Rattus norvegicus)Moringa (Moringa oleifera L). is a plant that is known for its multipurpose, nutrient-dense, and medicinal properties. Moringa leaves contain flavonoid compounds, namely β-sitosterol which can reduce ulcers in the stomach. This research used 15 male white rats divided into 5 groups, namely the normal group, CMC Na (Negative), ranitidine (Positive), and treatment with extract doses of 100 and 300 mg/kg BW. Test animals were induced by aspirin at a dose of 500 mg/kg for 7 days, then given treatment for 7 days, except for the normal group. On the 15th day, all groups were sacrificed, then the gastric organs were visually observed, and the ulcer index was measured. the observations it was found that the administration of the extract at a dose of 300 mg/kgBB decreased the number of ulcers compared to the positive control group (p>0.05). The extract dose of 300 mg/kg BW reduces the number of aspirin-induced ulcer diameters. The results of statistics with Kruskall-Wallis, there was a significant difference after treatment (p<0.05), but there was no significant difference between groups (p>0.05). Ethanol extract of Moringa leaves at a dose of 300 mg/kgBB can be gastroprotective in aspirin-induced male white rats.Keyword: Moringa leaves, gastroprotective, gastric ulcer, aspirinKelor (Moringa oleifera L).merupakan tanaman yang dikenal multi guna, padat akan nutrisi dan bermanfaat sebagai obat. Daun kelor mengandung senyawa flavonoid, yakni β-sitosterol yang dapat mengurangi tukak pada lambung. Penelitian ini menggunakan tikus putih jantan sebanyak 15 ekor yang dibagi dalam 5 kelompok yaitu kelompok normal, Na CMC (Negatif), ranitidine (Positif), dan perlakuan dengan dosis  ekstrak 100 dan 300 mg/kgBB. Hewan uji di induksi aspirin dosis 500 mg/kgBB selama 7 hari, kemudian diberi pengobatan selama 7 hari, kecuali kelompok normal. Pada hari ke-15 semua kelompok dikorbankan kemudian diamati organ lambung secara visual diukur indeks tukak. Dari hasil pengamatan diketahui bahwa pemberian ekstrak dosis 300 mg/kgBB terjadi penurunan jumlah tukak dibandingkan dengan kelompok kontrol positif  (p>0,05). Dosis ekstrak 300 mg/kgBB memberikan efek penurunan jumlah diameter tukak akibat induksi aspirin. Berdasarkan hasil perhitungan dengan Kruskall-Wallis menunjukkan adanya perbedaan yang signifikan setelah perlakuan (p<0,05), namun tidak menunjukkan perbedaan signifikan antar kelompok (p>0,05). Ekstrak etanol daun kelor dengan dosis 300 mg/kgBB memiliki kemampuan sebagai gastroprotektif pada tikus putih  jantan yang diinduksi aspirin.Keyword : Daun kelor, gastroprotektif, tukak lambung, aspirin
Edukasi Pencegahan Penyakit Skabies Melalui Peer Educator Di Sekolah Enterpreneur Tahfidz Kekasih Al-Aqsha, Gowa, Sulawesi Selatan Muslimin, Lukman; Marwati, Marwati; Mus, Suwahyuni; Rosyid, Sujud Z; Irwana, Rina; Djamaluddin, Suci F; Khairi, Nur; Indrisari, Maulita; Nursamsiar, Nursamsiar; Megawati, Megawati; Imrawati, Imrawati; Nur, Syamsu; Sami, Fitriyanti; Amin, Astuti; Paluseri, Andi
Jurnal Pengabdian Kefarmasian Vol 4, No 2 (2023): JURNAL PENGABDIAN KEFARMASIAN
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jpk.v4i2.3421

Abstract

Scabies Prevention Through Peer Educators At The Entrepreneur School Of Tahfidz Kekasih Al-Aqsha, Gowa, South SulawesiBased on a survey that was carried out, it was found that there were incidents of head lice and scabies infections at the Tahfidz Kekasih Al-Aqsa Entrepreneurial School, in Pattallassang, Kab. Gowa, South Sulawesi. This shows that the student's knowledge of this disease is still low. So it is necessary to carry out outreach to increase students' knowledge of the dangers of scabies and its treatment. 45 students and 5 teachers attended this counseling. The methods used in this service are lecture, question and answer, and scabies examination. The presentation of material about scabies was carried out using PowerPoint media, after which the material continued with a question-and-answer session. At the end of the activity, a health examination was carried out to identify and provide treatment to students and teachers who suffered from scabies. The results of the counseling showed that 2 students were suffering from scabies. The counseling was considered successful because the students answered all the questions (100%).Keywords: Counseling, Peer Education, Scabies Berdasarkan survei yang telah dilakukan ditemukan adanya kejadian infeksi kutu rambut dan skabies (kudis) di Sekolah Enterpreneur Tahfidz Kekasih Al-Aqsha, di Pattallassang, Kab. Gowa, Sulawesi Selatan. Hal ini menunjukkan masih rendahnya pengetahuan para santri terhadap penyakit tersebut. Maka perlu dilakukan sosialisasi untuk meningkatkan pengetahuan santri terhadap bahaya penyakit skabies serta pengobatannya. Penyuluhan ini diikuti oleh 45 orang santri dan 5 orang guru. Metode yang digunakan dalam pengabdian ini adalah metode ceramah, tanya jawab, dan pemeriksaan skabies. Pemaparan materi tentang skabies dilakukan menggunakan media PowerPoint, setelah pemaparan materi dilanjutkan dengan sesi tanya jawab. Di akhir kegiatan, dilakukan pemeriksaan kesehatan untuk mengetahui dan memberikan pengobatan kepada santri maupun guru yang menderita skabies. Hasil penyuluhan menunjukkan bahwa ada 2 orang santri yang menderita skabies. Penyuluhan dinilai berhasil karena semua pertanyaan yang diberikan berhasil dijawab oleh santri (100%).Kata kunci : Penyuluhan, Peer Education, Skabies
Co-Authors Arisah, Arisah Astuti Amin, Astuti Awaluddin, Akbar Djamaluddin, Suci F Irwana, Rina Marwati Marwati, Marwati Mar’atun Jannah, Imrawati, Muzakkir Baitz, Maulita Indrisari, Maulita Megawati - Mus, Suwahyuni Muslimin, Lukman Nursamsiar Nursamsiar paluseri, Andi Rosyid, Sujud Z Sami, Fitriyanti Sapra, Amriani Syamsu Nur, Syamsu Tawali, Suryani