Kristanty, Ruth Elenora
Jurusan Analisa Farmasi dan Makanan Politeknik Kesehatan Kemenkes Jakarta II

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Aktivitas Antioksidan dan Penghambat Xantin Oksidase dari Ekstrak Buah Andaliman (Zanthoxylum acanthopodium DC.) Kristanty, Ruth Elenora; Mun'im, Abdul; Katrin, .
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 6, No 3 (2013)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.683 KB)

Abstract

The fruits of andaliman (Zanthoxylum acanthopodium DC.) are well known in North Sumatera and commonly used as seasoning for Batak traditional cuisine. Aims of this study were to determine the scavenging activity of free radicals and xanthine oxidase inhibitory activity from the andaliman fruit extracts after macerated garually in petroleum ether, dichloromethane, ethyl acetate, n-butanol, and methanol. Activity assay were evaluated in vitro by using DPPH and enzyme xanthine oxidase. The result showed that n-butanol extract has medium antioxidant activity with IC50 values of 53.51 μg/mL and methanol extract has strong antioxidant activity with IC50 values of 26.39 mg/mL. Xanthine oxidase inhibitory activity of the extract given by n-butanol and methanol are very strong with IC50 values of 3.69 μg/mL and 4.03 μg/mL. Keywords : antioxidant, free radical, xanthine oxidase, Zanthoxylum acanthopodium DC.  
AKTIVITAS ANTIJERAWAT DARI LOTION LENDIR BEKICOT (ACHATINA FULICA) Ristiawati, Nita; Kristanty, Ruth Elenora
Jurnal Farmasi Indonesia Vol 9, No 1 (2017)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5521.153 KB) | DOI: 10.35617/jfi.v9i1.554

Abstract

ABSTRAK : Lendir bekicot (Achatina fulica) dalam bentuk lotion telah diuji secara ilmiah aktivitasnya terhadap bakteri penyebab infeksi jerawat. Penelitian bertujuan menghasilkan formula lotion lendir bekicot yang bisa mengobati jerawat. Metode pengujian antibakteri menggunakan turbidimetri. Evaluasi sediaan yang dilakukan meliputi pengamatan organoleptik dan pH, ujidaya sebar dan uji daya lekat. Berdasarkan hasil pengujian yang telah dilakukan, lendir bekicot dan lotion lendir bekicot memiliki aktivitas antibakteri terhadap Propionibacterium acnes. Lotion lendir bekicot yang menghasilkan efek anti jerawat paling baik adalah yang mengandung konsentrasi lendir 16%. Sediaan lotion memiliki karakteristik, daya sebar, dan daya rekat yang baik. Bentuk sediaan stabil dalam penyimpanan suhu kamar selama lima minggu.
Aktivitas Antioksidan dan Penghambat Xantin Oksidase dari Ekstrak Buah Andaliman (Zanthoxylum acanthopodium DC.) Kristanty, Ruth Elenora; Mun'im, Abdul; Katrin, .
Jurnal Farmasi Indonesia Vol 6, No 3 (2013)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.683 KB) | DOI: 10.35617/jfi.v6i3.133

Abstract

The fruits of andaliman (Zanthoxylum acanthopodium DC.) are well known in North Sumatera and commonly used as seasoning for Batak traditional cuisine. Aims of this study were to determine the scavenging activity of free radicals and xanthine oxidase inhibitory activity from the andaliman fruit extracts after macerated garually in petroleum ether, dichloromethane, ethyl acetate, n-butanol, and methanol. Activity assay were evaluated in vitro by using DPPH and enzyme xanthine oxidase. The result showed that n-butanol extract has medium antioxidant activity with IC50 values of 53.51 μg/mL and methanol extract has strong antioxidant activity with IC50 values of 26.39 mg/mL. Xanthine oxidase inhibitory activity of the extract given by n-butanol and methanol are very strong with IC50 values of 3.69 μg/mL and 4.03 μg/mL. Keywords : antioxidant, free radical, xanthine oxidase, Zanthoxylum acanthopodium DC.  
PENINGKATAN KAPASITAS LINTAS ORGANISASI MELALUI INTERPROFESSIONAL EDUCATION SEBAGAI UPAYA PENCEGAHAN STUNTING Kristanty, Ruth Elenora; Wiyono, Sugeng; Saputra, Atang; Junaedi, Junaedi; Marsigit, Didik
JMM (Jurnal Masyarakat Mandiri) Vol 5, No 5 (2021): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (560.133 KB) | DOI: 10.31764/jmm.v5i5.5244

Abstract

Abstrak: Kegiatan peningkatan kapasitas lintas organisasi sosial sebagai upaya pencegahan stunting ini dimaksudkan untuk membantu menyelesaikan masalah stunting yang dihadapi oleh masyarakat kelurahan di wilayah lokus stunting Kelurahan Lenteng Agung, Kecamatan Jagakarsa, Jakarta Selatan. Pengabdian masyarakat ini bertujuan untuk mendapatkan hasil peningkatan pengetahuan melalui penyuluhan keamanan pangan sebagai upaya penanganan stunting. Pelaksanaan kegiatan bersifat komprehensif dan multisektoral yang mampu menuntun masyarakat ke arah kehidupan yang lebih dinamis serta mempermudah akses terhadap informasi dan ilmu pengetahuan. Program dilaksanakan dalam bentuk kerja sama yang sinergis tim dosen Poltekkes Kemenkes Jakarta II dari berbagai bidang keilmuan dengan sasaran kelompok masyarakat yang berada di kelurahan Lenteng Agung Jakarta Selatan, melalui intervensi lintas profesi dalam rangka menerapkan Interprofessional Education (IPE). Metode yang digunakan dalam kegiatan pengabdian masyarakat ini adalah ceramah untuk memberikan edukasi mengenai keamanan pangan. Untuk mengukur adanya perubahan peningkatan pengetahuan digunakan instrumen berupa test form yang dilakukan sebelum dan sesudah penyuluhan. Penyuluhan dihadiri sejumlah kader secara tatap muka terbatas dan secara daring melalui tautan pertemuan yang disediakan oleh pihak kelurahan. Hasil perhitungan penyuluhan keamanan pangan menggambarkan adanya peningkatan nilai pengetahuan sebesar 17,85% dengan kategori cukup baik. Berdasarkan pelaksanaan kegiatan Program Pendampingan Desa Mitra tahun 2021 dapat disimpulkan bahwa terjadi peningkatan pengetahuan responden dalam kegiatan penyuluhan keamanan pangan keluarga yang dapat meningkatkan status kesehatan masyarakat sebagai salah satu upaya intervensi untuk pencegahan stunting. Abstract:  Capacity-building activity across social organizations to prevent stunting was intended to help solve the problem of stunting faced by the village community in the stunting locus area of Lenteng Agung Village, Jagakarsa Sub-district, South Jakarta. This community service aimed to get the results of increasing knowledge through food safety counseling to handle stunting. The implementation of activities was comprehensive and multisectoral, which was able to lead society towards a more dynamic life and facilitate access to information and science. The program was implemented in the form of synergistic cooperation of a team of lecturers of Poltekkes Kemenkes Jakarta II from various scientific fields with the target of community groups located in the Lenteng Agung area, through cross-professional intervention to implement Interprofessional Education (IPE). The method used in this community service was a lecture to educate about food safety. The team used instruments of test forms conducted before and after counseling to measure the knowledge improvement. The activity was attended offline by a limited number of participants who implemented health protocols and online meeting through the link provided by the partner. The results of food safety counseling in community service activity illustrated an increase in knowledge by 17.85% with the category of moderate understanding. Based on the program's implementation in 2021, it concluded that there was an increase in respondents' knowledge in food safety counseling activity that could improve public health status as one of the intervention efforts to prevent stunting.Â