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Maharani
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PEMURNIAN BIOGAS KOTORAN SAPI MENGGUNAKAN ABSORBER DAN ADSORBER KARBON AKTIF Aris Fiatno; Maharani; Aprizal
Aptek Jurnal Apliksai Teknologi (APTEK): Volume 12, No. 01, Januari 2020
Publisher : Fakultas Teknik Universitas Pasir Pengaraian

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.055 KB) | DOI: 10.30606/aptek.v12i1.238

Abstract

SP 1 Laboy Jaya village in Bangkinang sub-district, Kampar Regency, Riau province is one of the transmigration areas of oil palm plantations, most of the residents work as farmers. In this research will utilize cow dung collected by farmers to be invented as an alternative energy in the form of biogas to substitute petroleum energy derived from fossil fuels, so that people in the village will no longer need to buy LPG gas. Equipment used in the biogas purification process with: Absorber Ca (OH) 2, activated carbon absorber. The adsorption process facilitates the absorption of CO2 on the surface of the adsorbent compared to CH4 absorption. The decrease in CO2 levels on the other hand increases the rate of CH4 in this case the CH4 element has flammable properties. The results of the Beginner Lecturer Research scheme are at the TKT level 1 to 6 with the outcomes being; Appropriate technology.
PERBEDAAN PERTUMBUHAN DAN KELANGSUNGAN HIDUP IKAN LELE SANGKURIANG (Clarias gariepinus var) AKIBAT PEMBERIAN PAKAN BERBASIS TEPUNG DAUN LAMTORO Asni; Rahim; Anti Landu; Ramlah; Maharani; Mustafa R; Irfan
Techno-Fish Vol 6 No 2 (2022): TECHNO-FISH
Publisher : TECHNO-FISH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25139/tf.v6i2.5310

Abstract

Ikan lele sangkuriang merupakan salah satu komoditas perikanan air tawar yang banyak dibudidayakan di Indonesia karena permintaan yang terus meningkat. Meningkatnya permintaan ikan lele akan berdampak pada sektor budidaya karena dalam kegiatan budidaya kendala yang dihadapi adalah mahalnya harga pakan dan ketersediaan pakan dalam jumlah yang cukup. Upaya untuk mengurangi biaya pakan, sebagian pembudidaya menggunakan bahan pakan alternatif sebagai pengganti bahan pakan. Lamtoro merupakan sumber daya hayati lokal yang potensial untuk digunakan sebagai pakan dengan dihasilkan limbah hijauan bernilai nutrisi yang cukup tinggi dan mudah dicerna. Penelitian ini bertujuan untuk mengetahui laju pertumbuhan dan kelangsungan hidup ikan lele sangkuriang menggunakan pakan komersial, pakan tepung daun lamtoro dan pakan tepung daun lamtoro fermentasi. Metode yang digunakan adalah rancangan acak lengkap dengan tiga perlakuan dan tiga ulangan. Perlakuan A pakan komersial, B tepung daun lamtoro, C tepung daun lamtoro fermentasi. Parameter yang diukur adalah pertumbuhan berat mutlak, laju pertumbuhan spesifik, kelangsungan hidup dan rasio konversi pakan. Hasil analisis ragam menunjukkan bahwa pemberian pakan yang berbeda signifikan terhadap pertumbuhan berat mutlak, laju pertumbuhan spesifik dan rasio konversi pakan, namun tidak signifikan terhadap kelangsungan hidup ikan lele sangkuriang (Clarias gariepinus var). Pemberian pakan tepung daun lamtoro fermentasi memberikan hasil tertinggi untuk pertumbuhan berat mutlak pertumbuhan spesifik.
Potensi Penyimpanan Karbon pada Lamun Thalassia Hempricii di Perairan Tanggetada, Kabupaten Kolaka Ilham Antariksa Tasabaramo; Riska; Laode Abdul Fajar Hasidu; Aditya Hikmat Nugraha; Hasan Eldin Adimu; Maharani; Putri Cahyani
JSIPi (JURNAL SAINS DAN INOVASI PERIKANAN) (JOURNAL OF FISHERY SCIENCE AND INNOVATION) Vol 7 No 1 (2023): JURNAL SAINS dan INOVASI PERIKANAN
Publisher : Pascasarjana Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/jsipi.v7i1.76

Abstract

Thalassia hempricii merupakan lamun yang memiliki sebaran dan kerapatan yang tinggi di perairan Kecamatan Tanggetada. Beberapa studi mengatakan, lamun ini memiliki kontribusi yang besar terhadap penyerapan karbon di atmosfer. Oleh karena itu, perlu dilakukan penelitian mengenai potensi penyimpanan karbon pada lamun Thalassia Hempricii. Tujuan dari penelitian ini adalah mengetahui seberapa besar lamun Thalassia Hempricii menyimpan karbon, baik pada bagian atas lamun maupun bagian bawah lamun. Metode yang digunakan untuk menghitung karbon adalah dengan metode faktor konversi biomassa ke karbon. Lokasi penelitian dilakukan di 3 stasiun yaitu Kelurahan Tanggetada, Desa Palewai dan Kelurahan Anaiwoi. Hasil penelitian menunukkan bahwa kandungan karbon yang tersimpan pada lamun Thalassia hempricii adalah sebesar 362,54 gC/m2. Karbon yang tersimpan pada lamun bagian bawah lebih besar dibandingkan lamun bagian atas. Karbon yang tersimpan pada lamun bagian bawah berkisar antara 79, 60-497 gC/m2 dan pada lamun bagian atas berkisar antara 17,50-131,43 gC/m2.
EARLY POSTOPERATIVE COMPLICATION FOLLOWING FILTRATION SURGERY IN DR. KARIADI GENERAL HOSPITAL SEMARANG 2020-2022: Oral Presentation - Observational Study - Resident Mazidah Zulfa; Denti Puspasari; Maharani; Fifin L Rahmi
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/742jnq25

Abstract

Introduction & ObjectivesFiltration surgery is the most frequent surgery in managing glaucoma. Although trabeculectomy isgenerally a safe and effective procedure, complications can occur. The purpose of the study was todescribe the early postoperative complications in patients who had undergone filtration surgery. MethodsThis study was a retrospective study that uses secondary data from electronic medical records ofpatients who had filtration surgery between January 1, 2020, and December 31, 2022, in KariadiHospital Semarang. Preoperative data include age, gender, visual acuity, intraocular pressure, andtype of glaucoma. The incidence of early postoperative complications was described up to 3 weeks offollow-up. Results287 eyes were obtained from 266 patients who underwent filtration surgery. 168 eyes (58.5%) hadphaco-trabeculectomy, 117 eyes (40.77%) had trabeculectomy and 2 eyes (0.7%) had ECCEtrabeculectomy.Primary angle closure glaucoma (126 eyes, 43.9%) was the most common type ofglaucoma treated with filtration surgery. During the 3-week follow-up period, 93 eyes (32.4%)experienced an early complication with trabeculectomy being more common (17.42%) thancombined surgery. The commonest complication found was hypotony in 69 eyes (24%). Othercomplications include hyphema (3.14%), transient intraocular pressure elevation (3.14%), blebleakage (2.09%), suprachoroidal haemorrhage (0.7%), subhyaloid haemorrhage (0.35%) and retinalhaemorrhage (0.35%). ConclusionThis study found the most common early postoperative complication of filtration surgery washypotony. This complication occurs frequently after trabeculectomy.
Inhibition of Caspase-3 Provides Neuroprotection for Retina Ganglion Cells againts NMDA-induced Exitotoxicity in Wistar Rats: Oral Presentation - Observational Study - Resident Andriati Nadhilah Widyarini; Maharani; Fifin L Rahmi; Trilaksana Nugroho; Arnila Novitasari Saubig; Hermawan Istiadi
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/fs7v9v35

Abstract

Introduction & ObjectivesGlaucoma is a disorder characterized by the presence of optic neuropathy. Visual impairment inglaucoma is caused by retinal ganglion cell (RGC) apoptosis associated with N-methyl-D-aspartate(NMDA)-mediated excitotoxicity. Excitotoxicity causes an increase in calcium in cells as well asactivation of caspase-3. Glaucoma therapy is currently given to reduce intraocular pressure (IOP),but the damage is still progressing progressively. Hesperidin is known as a neuroprotector that cansuppress calpain overactivation in NMDA-treated retina, thereby reducing the upregulation of TNF-,an inflammatory cytokine, inhibiting calpain activation by suppressing oxidative stress, andattenuating caspase-3 activation. The aim of this study to proving the effect of oral Hesperidin on theexpression of caspase-3 Retinal Ganglion Cell in Wistar rats model of NMDA-induced glaucoma. MethodsExperimental research with post test design only randomized control trial Wistar rats with NMDAinduction were divided into 2 treatment and control groups. The treatment group was given oralHesperidin at a dose of 100mg/kg/day while the control group was given Na-CMC 182 mg/kg/day for3 weeks. Retinal caspase-3 expression was examined by immunohistochemical staining. Data werecollected and processed and then the Mann- Whitney test was performed. (significant p<0.05) ResultsThe mean percentage and intensity of RGC caspase-3 expression in the treatment group were 4.29 ±0.49 it was significantly lower than the control group 6.29 ± 0.95 (p value = 0.003). ConclusionHesperidin provides neuroprotection for RGC againts NMDA- induced exitotoxicity by inhibition ofcaspase-3.
SURGICAL THERAPHY FOR PRIMARY GLAUCOMA IN DR. KARIADI GENERAL HOSPITAL SEMARANG DURING JANUARY 2020 TO DECEMBER 2022: Oral Presentation - Observational Study - Resident Zeta Aisyah Bestari; Maharani; Denti L. Puspasari; Fifin L. Rahmi
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tcr6p578

Abstract

Introduction & ObjectivesGlaucoma can be treated with medicamentose, non invasive surgery, and invasive surgery. Thisstudy aim to determine the frequency and type of invasive surgery for primary glaucoma in Dr.Kariadi General Hospital during January 2020 to December 2022. MethodsThis was a descriptive research using secondary data obtained from electronic medical records,consist of gender, age, diagnosis, and type of surgery. The sample were taken with purposivesampling which are fullfill the inclusion criteria. ResultsThere were total of 395 eyes (395 patients) with primary glaucoma who underwent surgery, consistof 33% patients with open angle glaucoma (POAG) and 67% patients with angle closure glaucoma(PACG). Most common surgical theraphy for POAG was trabeculectomy (37%), followed bycombination of trabeculectomy and cataract surgery (32%), cataract surgery (16%),cyclocryotheraphy (10%), implantation of glaucoma drainage device (4%), and goniosynechialysis(1%). For PACG, most often used was combination of trabeculectomy and cataract surgery (61%),cataract surgery (13%), cyclocryotheraphy (12%), trabeculectomy (11%), combination of cataractsurgery and goniosynechialysis (2%), and implantation of glaucoma drainage device (1%). ConclusionThe most common type of surgery was trabeculectomy for primary open angle glaucoma andcombination of trabeculectomy and cataract surgery for primary angle closure glaucoma.
NEUROPROTECTIVE ROLE OF VITAMIN D3 ON GANGLION CELL-INNER PLEXIFORM LAYER THICKNESS IN NMDA-INDUCED RETINAL EXCITOTOXICITY MODEL OF GLAUCOMA: (Experimental Study on Wistar Rats Glaucoma Model with N-Methyl-D-Aspartate induction) Ezra Margareth; Trilaksana Nugroho; Andhika Guna Dharma; Fifin L Rahmi; Maharani; Hermawan Istiadi
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/6xrxsv34

Abstract

Introduction & ObjectivesRetinal ganglion cell (RGC) damage can affect the thinning of the GCC layers, which is the nervefiber layer, the ganglion cell layer and the inner plexiform layer. The loss of RGC and inner plexiformlayer (IPL) is strongly correlated with the loss of visual field defect. RGC and inner plexiform layerare potential targets to evaluate the progression of glaucoma. Glaucoma treatment not only focus onreducing IOP. Decreasing IOP according to the target pressure often can’t stop the process of RGCdamage and make it permanently and irreversible. Vitamin D3 is known as neuroprotector which hasthe ability to protect RGC and prevent layer thinning of GC-IPL in retina. The aim of this study is todetermine the effect of oral Vitamin D3 on the GC- IPL layer thickness in retinal of Wistar rats withNMDA-induced glaucoma model. MethodsGlaucoma Wistar rats were divided into 2 groups. The treatment group was given oral Vitamin D3 ata dose of 500 IU/kgBW/day for 10 weeks. GC-IPL layer thickness in retinal was examined byHematoxylin Eosin staining. Data were collected and processed then used with Independent T Test.(significant p<0.05) ResultsThe mean GC-IPL layer Thickness in the treatment group was 77,59 ± 15,15 ?m and 35,32 ± 4,04?m in the control group. There was a significant different between two group ( p = <0,001 ) ConclusionVitamin D3 has a neuroprotective effect on ganglion cell-inner plexiform layer Wistar rats in NMDAinducedexcitotoxicity model of glaucoma
Effect of Vitamin D3 on Caspase-3 Expression of Retinal Ganglion Cell Wistar Rats with N-Methyl-D-Aspartate-induced Model of Glaucoma Seia Mahanani; Maharani; Arnila Novitasari Saubig; Winarto; Andhika Guna Dharma; Hermawan
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/4zctdm27

Abstract

Introduction & ObjectivesIntroduction: Vitamin D is a neuroprotective neurosteroid hormone with antioxidant, antiinflammatoryand anti-ischemic properties that can reduce the entry of intracellular calcium,thereby reducing cytochrome-c, modulating inflammation, increasing Nitric Oxide production bysuppressing oxidative stress and activating caspase-3 activation. Excitotoxicity due to N-Methyl-DAspartatecauses caspase-3 activation due to increased calcium in cells and describes thepathogenesis of vascular factor glaucoma due to retinal ganglion cell (RGC) damage in the absenceof an increase in intraocular pressure. RGC damage can be assessed by the expression of caspase-3which is a proapoptotic agent that acts as the main effector caspase in the mechanism of apoptosis.Objective: Proving the effect of vitamin D3 on caspase-3 expression of retinal ganglion cells wistarrats in NMDA-induced glaucoma models. MethodsAn experimental study, using post-test only randomized controlled group design, was done on 14male NMDA-induced glaucoma wistar rats, divided into 2 groups. The treatment group was givenoral vitamin D3 500 IU/kgBW every 24 hours for 10 weeks, while the control group was givenaquadest. Immunohistochemistry was used to measured caspase-3 expression. Mann-Whitneyanalized non-parametric difference test (Significant p<0.05). ResultsCaspase-3 expression of retinal ganglion cell was significantly lower (p=0.004) in treatment group(mean=5,29 ± 0,76) compared to control group (mean=6,71 ± 0,49). ConclusionOral vitamin D3 has an effect on caspase-3 expression of retinal ganglion cells wistar rats in NMDAinducedglaucoma models. Further research is needed to investigate the protective role of vitaminD3 on glaucoma patients.
Successful Rate of Glaucoma Surgery in Secondary Glaucoma after Vitrectomy in Kariadi General Hospital Semarang 2020-2022: Oral Presentation - Observational Study - Resident Nur Azizah Intan Putri Ismail; Maharani; Fifin L. Rahmi; Denti Puspasari
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/01mhar90

Abstract

Introduction & ObjectivesGlaucoma is one of the most frequent complications of vitrectomy surgery. It can cause a significantrise in intraocular pressure (IOP). Glaucoma surgery can be planned in medically uncontrolledglaucoma. Trabeculectomy and Glaucoma Drainage Device (GDD) implantation are the mostfrequent filtering surgeries used in these cases. This study aims to define the success rate ofglaucoma surgery in secondary glaucoma after vitrectomy. MethodsThis study is an analytical observational study with retrospective data collection held from medicalrecords of patients with secondary glaucoma after vitrectomy who underwent glaucoma surgery inKariadi General Hospital Semarang from 2020-2022. Surgical success defined by postoperative IOPreduced by>20% from baseline, with or without anti-glaucoma medication. ResultsThere were 16 eyes of trabeculectomy with 5-fluorouracil (5-FU), and 8 eyes of GDD implants. Themean preoperative IOP was 43.76+6.77 mmhg for trabeculectomy 5-FU, and 42.43+4.02 mmhg forGDD implant. IOP levels in both groups varied significantly after one day, one week, one month, andthree months after surgery (p<0.05). The success rate for the trabeculectomy 5-FU group was81.25% and the GDD implant group was 87.5% in 3 months. There was no statistically significantdifference in the success rate between the trabeculectomy 5-FU and GDD implant groups (p=0.839).The complication for the GDD implant group was 25%. No complications were found in thetrabeculectomy 5-FU group. ConclusionThere was no significant difference in the success rate between trabeculectomy 5-FU and the GDDimplant group. Both groups are viable for glaucoma surgery in secondary glaucoma after vitrectomysurgery.
Trabeculectomy Versus Tube Outcome in Neovascular Glaucoma: Oral Presentation - Observational Study - Resident Daisy Syakhsiatusy Syahiqoh; Fifin Luthfia Rahmi; Denti Puspasari; Maharani
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/73qxtp82

Abstract

Introduction & ObjectivesNeovascular glaucoma (NVG) is known to be a refractory form of glaucoma, which frequentlyrequires the integrated use of medical, laser and incisional surgery. Tube-shunt implantation andtrabeculectomy with antifibrotic agent are the two most-popular incisional procedures for managingrefractory glaucoma. This study aims to compare surgical outcome between patients who underwenttrabeculectomy versus tube-shunt implantation for the treatment of NVG. MethodsA retrospective study was held of NVG patients that underwent trabeculectomy and tube-shuntimplantation between January 2020 - December 2022 at Dr. Kariadi Hospital, Semarang. IOPoutcome and success rate was measured at 3 months post operatively. Statistical analysis was usedto compare the outcome between groups, p<0.05 was considered significant. ResultsThere were no significant differences in characteristics between groups at baseline. Mean IOPmeasured at 3 months post operatively was 18.58 ± 5.53 and 15.94 ± 10.79 in trabeculectomy andtube group respectively (p=0.04), complete success rate was 18.8% in trabeculectomy and 25% intube group, qualified success rate was 37.5% in trabeculectomy and 56.3% in tube group. Greaterfailure rate was observed in trabeculectomy group (43.8%). ConclusionCompared to trabeculectomy, tube-shunt implantation has lower IOP at 3 months post operatively inNVG. Greater failure rate was observed in trabeculectomy.
Co-Authors Aditya Hikmat Nugraha Andhika Guna Dharma Andriati Nadhilah Widyarini Anti Landu Aprizal Arief Wildan Aris Fiatno Arnila Novitasari Saubig Asni Asni Daisy Syakhsiatusy Syahiqoh Denti L. Puspasari Denti Puspasari Ezra Margareth Fifin L Rachmi Fifin L Rahmi Fifin L. Rahmi Fifin Luthfia Rahmi Hasan Eldin Adimu Hasidu, La Ode Abdul Fajar HERMAWAN Hermawan Istiadi Ilham Antariksa Tasabaramo Irfan Mazidah Zulfa Mustafa R Nur Azizah Intan Putri Ismail Putri Cahyani Rahim Rahim Ramlah Rina Apriliana Riska Satya Hutama P Seia Mahanani Trilaksana Nugroho WINARTO Zeta Aisyah Bestari